Adv Pharm Bull. 2014;4(6):483-491.
doi: 10.5681/apb.2014.072
PMID: 25671179
PMCID: PMC4312395
Scopus id: 84921983649
  Abstract View: 344
  PDF Download: 183

Review Article

Bolaamphiphiles: A Pharmaceutical Review

Mayur Fariya 1, Ankitkumar Jain 1, Vivek Dhawan 1, Sanket Shah 1, Mangal S. Nagarsenker 1 *

1 Department of Pharmaceutics, Bombay College of Pharmacy, Kalina, Santacruz (E), Mumbai – 400098, India.

Abstract

The field of drug discovery is ever growing and excipients play a major role in it. A novel class of amphiphiles has been discussed in the review. The review focuses on natural as well as synthetic bolaamphiphiles, their chemical structures and importantly, their ability to self assemble rendering them of great use to pharmaceutical industry. Recent reports on their ability to be used in fabrication of suitable nanosized carriers for drug as well as genes to target site, has been discussed substantially to understand the potential of bolaamphiphiles in field of drug delivery.
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Submitted: 18 May 2014
Revised: 04 Aug 2014
First published online: 31 Dec 2014
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