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Adv Pharm Bull. 2016;6(2): 267-270. doi: 10.15171/apb.2016.037
PMID: 27478791        PMCID: PMC4961987

Short Communication

Fisetin Protects DNA Against Oxidative Damage and Its Possible Mechanism

Tingting Wang, Huajuan Lin, Qian Tu, Jingjing Liu, Xican Li *

Cited by CrossRef: 10


1- Ahmad A, Ali T, Rehman S, Kim M. Phytomedicine-Based Potent Antioxidant, Fisetin Protects CNS-Insult LPS-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment. JCM. 2019;8(6):850 [Crossref]
2- Imai K, Nakanishi I, Ohkubo K, Ohno A, Mizuno M, Fukuzumi S, Matsumoto K, Fukuhara K. Synthesis and radical-scavenging activity of C-methylated fisetin analogues. Bioorganic & Medicinal Chemistry. 2019;27(8):1720 [Crossref]
3- Naeimi A, Alizadeh M. Antioxidant properties of the flavonoid fisetin: An updated review of in vivo and in vitro studies. Trends in Food Science & Technology. 2017;70:34 [Crossref]
4- Mishra J, Swain J, Mishra A. Probing the temperature-dependent changes of the interfacial hydration and viscosity of Tween20 : cholesterol (1 : 1) niosome membrane using fisetin as a fluorescent molecular probe. Phys Chem Chem Phys. 2018;20(19):13279 [Crossref]
5- Wang R, Li J, Niu D, Xu F, Zeng X. Protective effect of baicalein on DNA oxidative damage and its binding mechanism with DNA: An in vitro and molecular docking study. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2021;253:119605 [Crossref]
6- Christodoulou M, Villa F, Pinto A, Cappitelli F. Correlation between Perturbation of Redox Homeostasis and Antibiofilm Capacity of Phytochemicals at Non-Lethal Concentrations. Antioxidants. 2022;11(12):2451 [Crossref]
7- Rosiak N, Tykarska E, Cielecka-Piontek J. Mechanochemical Approach to Obtaining a Multicomponent Fisetin Delivery System Improving Its Solubility and Biological Activity. IJMS. 2024;25(7):3648 [Crossref]
8- Wang R, Hu X, Pan J, Zhang G, Gong D. Interaction of isoeugenol with calf thymus DNA and its protective effect on DNA oxidative damage. Journal of Molecular Liquids. 2019;282:356 [Crossref]
9- Hassan S, Samanta S, Dash R, Karpiński T, Habibi E, Sadiq A, Ahmadi A, Bungau S. The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress. Front Pharmacol. 2022;13 [Crossref]
10- Proshkina E, Shaposhnikov M, Moskalev A. Genome-Protecting Compounds as Potential Geroprotectors. IJMS. 2020;21(12):4484 [Crossref]
11- Łodyga-Chruscińska E, Pilo M, Zucca A, Garribba E, Klewicka E, Rowińska-Żyrek M, Symonowicz M, Chrusciński L, Cheshchevik V. Physicochemical, antioxidant, DNA cleaving properties and antimicrobial activity of fisetin-copper chelates. Journal of Inorganic Biochemistry. 2018;180:101 [Crossref]