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Adv Pharm Bull. 2015;5(5): 661-666. doi: 10.15171/apb.2015.090
PMID: 26793613        PMCID: PMC4708038

Original Research

Identification of Novel Single Chain Fragment Variable Antibodies Against TNF-α Using Phage Display Technology

Ali Akbar Alizadeh 1,2,3,4, Maryam Hamzeh-Mivehroud 5,2,4, Siavoush Dastmalchi 2,4 *

Cited by CrossRef: 6


1- Tsukamoto K, Ando T, Fuji D, Yokoyama T, Takamori Y, Horiuchi D, Iwamoto R, Yamamoto M, Kawakami T. In vitro display evolution of the PURE system-expressed TNFα-binding unnatural cyclic peptide containing an N-methyl-d-amino acid. Biochemical and Biophysical Research Communications. 2021;534:519 [Crossref]
2- Lei G, Xu M, Xu Z, Gu L, Lu C, Bai Z, Wang Y, Zhang Y, Hu H, Jiang Y, Zhao W, Tan S. A Novel Fully Human Agonistic Single Chain Fragment Variable Antibody Targeting Death Receptor 5 with Potent Antitumor Activity In Vitro and In Vivo. IJMS. 2017;18(10):2064 [Crossref]
3- Alizadeh A, Morris M, Church W, Yaqoubi S, Dastmalchi S. A mechanistic perspective, clinical applications, and phage-display-assisted discovery of TNFα inhibitors. Drug Discovery Today. 2022;27(2):503 [Crossref]
4- Zhang Y, Zhang P, He A, Yang Y, Wang J, Zhang H, Zhang W. Prokaryotic expression of MLAA-34 and generation of a novel human ScFv against MLAA-34 by phage display technology. Oncotarget. 2017;8(24):39077 [Crossref]
5- Eyvazi S, Kazemi B, Bandehpour M, Dastmalchi S. Identification of a novel single chain fragment variable antibody targeting CD24-expressing cancer cells. Immunology Letters. 2017;190:240 [Crossref]
6- Huen J, Yan Z, Iwashkiw J, Dubey S, Gimenez M, Ortiz M, Patel S, Jones M, Riazi A, Terebiznik M, Babaei S, Shahinas D. A Novel Single Domain Antibody Targeting FliC Flagellin of Salmonella enterica for Effective Inhibition of Host Cell Invasion. Front Microbiol. 2019;10 [Crossref]