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Adv Pharm Bull. 2016;6(1): 9-16. doi: 10.15171/apb.2016.03
PMID: 27099831        PMCID: PMC4833885

Original Research

The Effect of Various Vehicles on the Naproxen Permeability through Rat Skin: A Mechanistic Study by DSC and FT-IR Techniques

Anayatollah Salimi 1 * , Najme Hedayatipour 1, Eskandar Moghimipour 1

Cited by CrossRef: 21


1- Imran M, Iqubal M, Imtiyaz K, Saleem S, Mittal S, Rizvi M, Ali J, Baboota S. Topical nanostructured lipid carrier gel of quercetin and resveratrol: Formulation, optimization, in vitro and ex vivo study for the treatment of skin cancer. International Journal of Pharmaceutics. 2020;587:119705 [Crossref]
2- Kumbhar P, Manjappa A, Shah R, Nadaf S, Disouza J. Nanostructured Lipid Carrier–Based Gel for Repurposing Simvastatin in Localized Treatment of Breast Cancer: Formulation Design, Development, and In Vitro and In Vivo Characterization. AAPS PharmSciTech. 2023;24(5) [Crossref]
3- Niu X, Zhang D, Bian Q, Feng X, Li H, Rao Y, Shen Y, Geng F, Yuan A, Ying X, Gao J. Mechanism investigation of ethosomes transdermal permeation. International Journal of Pharmaceutics: X. 2019;1:100027 [Crossref]
4- Asghar A, Aamir M, Sheikh F, Ahmad N, Elsherif M, Abbas Bukhari S. Co-Combination of Pregabalin and Withania coagulans-Extract-Loaded Topical Gel Alleviates Allodynia and Hyperalgesia in the Chronic Sciatic Nerve Constriction Injury for Neuropathic Pain in Animal Model. Molecules. 2022;27(14):4433 [Crossref]
5- Wu W, Wang Z, Wu Y, Wu H, Chen T, Xue Y, Wang Y, Jiang C, Shen C, Liu L, Zhu H, Liu Q. Mechanisms of Penetration Enhancement and Transport Utilizing Skin Keratine Liposomes for the Topical Delivery of Licochalcone A. Molecules. 2022;27(8):2504 [Crossref]
6- Wang Z, Xue Y, Chen T, Du Q, Zhu Z, Wang Y, Wu Y, Zeng Q, Shen C, Jiang C, Yang Z, Zhu H, Liu L, Liu Q. Glycyrrhiza acid micelles loaded with licochalcone A for topical delivery: Co-penetration and anti-melanogenic effect. European Journal of Pharmaceutical Sciences. 2021;167:106029 [Crossref]
7- Lv J, Wu P, Fang Y, Zhang W, Liu D, Wu M, Shang L, Li H, Zhao Y. Deep Eutectic Solvents Based on L-Arginine and 2-Hydroxypropyl-β-Cyclodextrin for Drug Carrier and Penetration Enhancement. AAPS PharmSciTech. 2023;24(7) [Crossref]
8- Ullah I, Shah S, Khan M, Shah K, Khan B. Chitosan (Poly-(D) glucosamine) based solid lipid nanoparticles of dexibuprofen for topical delivery: Formulation development and characterizations. MGC. 2021;20(3):377 [Crossref]
9- Osborne D, Musakhanian J. Skin Penetration and Permeation Properties of Transcutol®—Neat or Diluted Mixtures. AAPS PharmSciTech . 2018;19(8):3512 [Crossref]
10- Xu Y, Cai Y, Meng Y, Wu L, Chen J, Cao W, Chu X. Liposome and microemulsion loaded with ibuprofen: from preparation to mechanism of drug transport. Journal of Microencapsulation. 2022;39(6):539 [Crossref]
11- Shah H, Nair A, Shah J, Jacob S, Bharadia P, Haroun M. Proniosomal vesicles as an effective strategy to optimize naproxen transdermal delivery. Journal of Drug Delivery Science and Technology. 2021;63:102479 [Crossref]
12- Asghar A, Aamir M, Sheikh F, Ahmad N, Alotaibi N, Bukhari S. Preparation, Characterization of Pregabalin and Withania coagulans Extract-Loaded Topical Gel and Their Comparative Effect on Burn Injury. Gels. 2022;8(7):402 [Crossref]
13- Ha E, Lee S, Choi D, Jeong S, Hwang S, Kim M. Application of diethylene glycol monoethyl ether in solubilization of poorly water-soluble drugs. J Pharm Investig. 2020;50(3):231 [Crossref]
14- Rostamkalaei S, Iman M, Ataee R, Bahari Z. The effects of Lavandula angustifolia essential oil on analgesic effects and percutaneous absorption of naproxen sodium gel; an in vivo and in vitro study. Clin Exp Pharma Physio. 2023;50(4):298 [Crossref]
15- Suñer-Carbó J, Calpena-Campmany A, Halbaut-Bellowa L, Clares-Naveros B, Rodriguez-Lagunas M, Barbolini E, Zamarbide-Losada J, Boix-Montañés A. Biopharmaceutical Development of a Bifonazole Multiple Emulsion for Enhanced Epidermal Delivery. Pharmaceutics. 2019;11(2):66 [Crossref]
16- SALIMI A, SHEYKHOLESLAMI S. The Effect of Herbal Penetration Enhancers on the Skin Permeability of Mefenamic Acid Through Rat Skin. tjps. 2023;20(2):108 [Crossref]
17- Park J, Kim J, Ho M, Park D, Kim E, Choi Y, Jang S, Kang M. Effect of Penetration Enhancers on Toenail Delivery of Efinaconazole from Hydroalcoholic Preparations. Molecules. 2021;26(6):1650 [Crossref]
18- Raeisi Estabragh M, Sajadi Bami M, Dehghannoudeh G, Noudeh Y, Moghimipour E. Cellulose derivatives and natural gums as gelling agents for preparation of emulgel-based dosage forms: A brief review. International Journal of Biological Macromolecules. 2023;241:124538 [Crossref]
19- Wang H, Tian Q, Quan P, Liu C, Fang L. Probing the Role of Ion-Pair Strategy in Controlling Dexmedetomidine Penetrate Through Drug-in-Adhesive Patch: Mechanistic Insights Based on Release and Percutaneous Absorption Process. AAPS PharmSciTech. 2020;21(1) [Crossref]
20- Lv J, Jiang M, Fang Y, Zhang W, Wu M, Zheng F, Lei K, Shang L, Zhao Y. The mimicked cell penetration peptides of chitosan derivates with low molecular weight for transdermal enhancement studies. European Polymer Journal. 2023;195:112197 [Crossref]
21- Iqbal B, Ali J, Baboota S. Silymarin loaded nanostructured lipid carrier: From design and dermatokinetic study to mechanistic analysis of epidermal drug deposition enhancement. Journal of Molecular Liquids. 2018;255:513 [Crossref]