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Adv Pharm Bull. 2015;5(4): 549-556. doi: 10.15171/apb.2015.074
PMID: 26819928        PMCID: PMC4729340

Original Research

Nanoethosomes for Dermal Delivery of Lidocaine

Soraya Babaie 1, Saeed Ghanbarzadeh 2, Soodabeh Davaran 3, Maryam Kouhsoltani 4, Hamed Hamishehkar 5 *

Cited by CrossRef: 26


1- PRATIWI R, MAHMUDAH D, SAPTARINI N, SUHERMAN M, MEGANTARA S. COMPARISON OF PARTITION COEFFICIENT (LOG P) OF DRUGS: COMPUTATIONAL AND EXPERIMENTAL DATA STUDY. Int J App Pharm. 2023;:155 [Crossref]
2- Ibrahim T, Abdallah M, El-Megrab N, El-Nahas H. Transdermal ethosomal gel nanocarriers; a promising strategy for enhancement of anti-hypertensive effect of carvedilol. Journal of Liposome Research. 2019;29(3):215 [Crossref]
3- Liu Y, Zhao Z, Liang L, Jing L, Wang J, Dai Y, Chen B, Guo X. Toward a solid microneedle patch for rapid and enhanced local analgesic action. Drug Deliv and Transl Res. 2024; [Crossref]
4- Hashempour S, Ghanbarzadeh S, Maibach H, Ghorbani M, Hamishehkar H. Skin toxicity of topically applied nanoparticles. Therapeutic Delivery. 2019;10(6):383 [Crossref]
5- Zoabi A, Touitou E, Margulis K. Recent Advances in Nanomaterials for Dermal and Transdermal Applications. Colloids and Interfaces. 2021;5(1):18 [Crossref]
6- Heydari S, Ghanbarzadeh S, Anoush B, Ranjkesh M, Javadzadeh Y, Kouhsoltani M, Hamishehkar H. Nanoethosomal formulation of gammaoryzanol for skin-aging protection and wrinkle improvement: a histopathological study. Drug Development and Industrial Pharmacy. 2017;43(7):1154 [Crossref]
7- Andreu V, Arruebo M. Current progress and challenges of nanoparticle-based therapeutics in pain management. Journal of Controlled Release. 2018;269:189 [Crossref]
8- Aliasgharlou L, Ghanbarzadeh S, Azimi H, Zarrintan M, Hamishehkar H. Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine. Adv Pharm Bull. 2016;6(4):581 [Crossref]
9- Zandi G, Lotfipour F, Ghanbarzadeh S, Medghalchi M, Hamishehkar H. A comparative study on the potentials of nanoliposomes and nanoethosomes for Fluconazole delivery. Journal of Drug Delivery Science and Technology. 2018;44:264 [Crossref]
10- Wang Y, Wang X, Wang X, Song Y, Wang X, Hao J. Design and Development of Lidocaine Microemulsions for Transdermal Delivery. AAPS PharmSciTech. 2019;20(2) [Crossref]
11- Anjum F, Zakir F, Verma D, Aqil M, Singh M, Jain P, Mirza M, Anwer M, Iqbal Z. Exploration of Nanoethosomal Transgel of Naproxen Sodium for the Treatment of Arthritis. CDD. 2020;17(10):885 [Crossref]
12- Stefanov S, Andonova V. Lipid Nanoparticulate Drug Delivery Systems: Recent Advances in the Treatment of Skin Disorders. Pharmaceuticals. 2021;14(11):1083 [Crossref]
13- Zhang D, Ye D, Jing P, Tan X, Qiu L, Li T, Shen L, Sun Y, Hou H, Zhang Y, Tian Q. Design, optimization and evaluation of co-surfactant free microemulsion-based hydrogel with low surfactant for enhanced transdermal delivery of lidocaine. International Journal of Pharmaceutics. 2020;586:119415 [Crossref]
14- Jin P, Yao R, Qin D, Chen Q, Du Q. Enhancement in Antibacterial Activities of Eugenol-Entrapped Ethosome Nanoparticles via Strengthening Its Permeability and Sustained Release. J Agric Food Chem. 2019;67(5):1371 [Crossref]
15- Hamidreza Kheiri M, Alimohammadi N, Danafar H. Preparation of biocompatible copolymeric micelles as a carrier of atorvastatin and rosuvastatin for potential anticancer activity study. Pharmaceutical Development and Technology. 2019;24(3):303 [Crossref]
16- Nosrati H, Javani E, Salehiabar M, Kheiri Manjili H, Davaran S, Danafar H. Biocompatibility and anticancer activity of L-phenyl alanine-coated iron oxide magnetic nanoparticles as potential chrysin delivery system. J Mater Res. 2018;33(11):1602 [Crossref]
17- Nasri S, Ebrahimi-Hosseinzadeh B, Rahaie M, Hatamian-Zarmi A, Sahraeian R. Thymoquinone-loaded ethosome with breast cancer potential: optimization, in vitro and biological assessment. J Nanostruct Chem. 2020;10(1):19 [Crossref]
18- Rahimpour Y, Javadzadeh Y, Hamishehkar H. Solid lipid microparticles for enhanced dermal delivery of tetracycline HCl. Colloids and Surfaces B: Biointerfaces. 2016;145:14 [Crossref]
19- Grimaldi N, Andrade F, Segovia N, Ferrer-Tasies L, Sala S, Veciana J, Ventosa N. Lipid-based nanovesicles for nanomedicine. Chem Soc Rev. 2016;45(23):6520 [Crossref]
20- Mota A, Rijo P, Molpeceres J, Reis C. Broad overview of engineering of functional nanosystems for skin delivery. International Journal of Pharmaceutics. 2017;532(2):710 [Crossref]
21- Meng S, Zhang C, Shi W, Zhang X, Liu D, Wang P, Li J, Jin Y. Preparation of osthole-loaded nano-vesicles for skin delivery: Characterization, in vitro skin permeation and preliminary in vivo pharmacokinetic studies. European Journal of Pharmaceutical Sciences. 2016;92:49 [Crossref]
22- Agrawal A, Joshi A, Bhattacharya S. Recent Excavation of Nanoethosomes in Current Drug Delivery. CDD. 2024;21(2):168 [Crossref]
23- Zhu T, Yu X, Yi X, Guo X, Li L, Hao Y, Wang W. Lidocaine-Loaded Hyaluronic Acid Adhesive Microneedle Patch for Oral Mucosal Topical Anesthesia. Pharmaceutics. 2022;14(4):686 [Crossref]
24- Yazdani-Arazi S, Ghanbarzadeh S, Adibkia K, Kouhsoltani M, Hamishehkar H. Histological evaluation of follicular delivery of arginine via nanostructured lipid carriers: a novel potential approach for the treatment of alopecia. Artificial Cells, Nanomedicine, and Biotechnology. 2017;45(7):1379 [Crossref]
25- Babaie S, Taghvimi A, Hong J, Hamishehkar H, An S, Kim K. Recent advances in pain management based on nanoparticle technologies. J Nanobiotechnol. 2022;20(1) [Crossref]
26- Yu Z, Lv H, Han G, Ma K, Santos H. Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation. PLoS ONE. 2016;11(7):e0159967 [Crossref]
27- Kim C, Jang E, Hong S, Yoon Y, Huh B, Kim S, Kim M, Moon H, Choy Y. Indwelling urinary catheter assembled with lidocaineā€loaded polymeric strand for local sustained alleviation of bladder discomfort. Bioengineering & Transla Med. 2021;6(2) [Crossref]