Eryngium Billardieri Induces Apoptosis via Bax Gene Expression in Pancreatic Cancer Cells

Neda Roshanravan ¹ , Parina Asgharian ^2,3 , Hassan Dariushnejad ⁴ , Naimeh Mesri Alamdari ⁵ , Behzad Mansoori ⁶ , Ali Mohammadi ⁶ , Shahriar Alipour ⁷ , Meisam Barati ⁸ , Abed Ghavami ⁹ , Vajihe Ghorbanzadeh ¹⁰ , Fatemeh Aamazadeh ⁹ , Alireza Ostadrahimi ⁹ *

Cited by CrossRef: 13

1- Yin X, Yang J, Chen J, Ni R, Zhou Y, Song H, Jin L, Tang T, Pan Y. LncRNA CTD-3252C9.4 modulates pancreatic cancer cell survival and apoptosis through regulating IFI6 transcription. Cancer Cell Int. 2021;21(1) [Crossref]

2- Nazeri M, Mirzaie-asl A, Saidijam M, Moradi M. Methanolic extract of Artemisia absinthium prompts apoptosis, enhancing expression of Bax/Bcl-2 ratio, cell cycle arrest, caspase-3 activation and mitochondrial membrane potential destruction in human colorectal cancer HCT-116 cells. Mol Biol Rep. 2020;47(11):8831 [Crossref]

3- Arslan A, Paşayeva L, Tugay O. Cytotoxic evaluation and LC-MS/MS analysis of aerial parts of Eryngium kotschyi Boiss. grown in Turkey. Braz J Pharm Sci. 2022;58 [Crossref]

4- Daneshzadeh M, Abbaspour H, Amjad L, Nafchi A. An investigation on phytochemical, antioxidant and antibacterial properties of extract from Eryngium billardieri F. Delaroche. Food Measure. 2020;14(2):708 [Crossref]

5- Alvarado T, Mariezcurrena Berasain M, Salem A, Pinzón Martínez D. Antimicrobial and Antioxidant Activities of Two Medicinal Plants Cuphea aequipetala var. hispida (Cav.) Koehne and Eryngium comosum Delaroche F Against Bacteria Related to Equine Infections. Journal of Equine Veterinary Science. 2020;94:103269 [Crossref]

6- Triantafillidis J, Triantafyllidi E, Sideris M, Pittaras T, Papalois A. Herbals and Plants in the Treatment of Pancreatic Cancer: A Systematic Review of Experimental and Clinical Studies. Nutrients. 2022;14(3):619 [Crossref]

7- Forouhandeh H, Rezaei Param Z, Molavi O, Asgharian P, Tarhriz V. Evaluation of anti-proliferative activity of Eryngium caucasicum on melanoma cancer cells. BMC Complement Med Ther. 2022;22(1) [Crossref]

8- Park M. Therapeutic Strategies for Pancreatic-Cancer-Related Type 2 Diabetes Centered around Natural Products. IJMS. 2023;24(21):15906 [Crossref]

9- Heidari A, Meftahi G, Bahrami F, Bahari Z, Zarei Mahmoudabadi A, Fallah Huseini H, Jangravi Z. Anti-Adipogenic Effects of Eryngium billardieri Extract during 3T3-L1 Adipocyte Differentiation. J Adv Med Biomed Res. 2023;31(147):391 [Crossref]

10- Hosseini K, Partovi Ariya M, Molavi O, Asgharian P, Tarhriz V. The Fractions of Eryngium thyrsoideum Extract Sensitize Breast Cancer Cells to Apoptosis. Jundishapur J Nat Pharm Prod. 2022;17(3) [Crossref]

11- Heydari Z, Sadeghi-Dinani M, Talebi A, Minaiyan M. Evaluation of anti-ulcerative effect of Eryngium billardieri extracts on experimental colitis in rats. Physiol Pharmacol. 2024;28(1):56 [Crossref]

12- Babich O, Samsuev I, Tsibulnikova A, Zemlyakova E, Popov A, Ivanova S, Noskova S, Sukhikh S. Properties of plant extracts and component composition: column chromatography and IR spectroscopy. 2024;12(2):373 [Crossref]

13- Das G, Das S, Talukdar A, Venil C, Bose S, Banerjee S, Shin H, Gutiérrez-Grijalva E, Heredia J, Patra J. Pharmacology and Ethnomedicinal Potential of Selected Plants Species from Apiaceae (Umbelliferae). CCHTS. 2023;26(2):256 [Crossref]

14- Sukhikh S, Asyakina L, Korobenkov M, Skrypnik L, Pungin A, Ivanova S, Larichev T, Larina V, Krol O, Ulrikh E, Chupakhin E, Babich O. Chemical Composition and Content of Biologically Active Substances Found in Cotinus coggygria, Dactylorhiza maculata, Platanthera chlorantha Growing in Various Territories. Plants. 2021;10(12):2806 [Crossref]

15- Haji Gholami M, Riyahi Malayeri S, ziloubaf A, Hassanpour H. High intensity interval training and Eryngium billardieri extract consumption on MMP-2 gene expression of visceral fat in rats with metabolic syndrome. jspac. 2022;2(3):17 [Crossref]

16- Alipour S, Pishkar L, Chaleshi V. Cytotoxic Effect of Portulaca Oleracea Extract on the Regulation of CDK1 and P53 Gene Expression in Pancreatic Cancer Cell Line. Nutrition and Cancer. 2022;74(5):1792 [Crossref]

17- Osqueei M, Mahmoudabadi A, Bahari Z, Meftahi G, Movahedi M, Taghipour R, Mousavi N, Huseini H, Jangravi Z. Eryngium billardieri extract affects cardiac gene expression of master regulators of cardiomyaopathy in rats with high fatdiet-induced insulin resistance. Clinical Nutrition ESPEN. 2023;56:59 [Crossref]