Tabriz University of Medical Sciences Advanced Pharmaceutical Bulletin 2228-5881 4 6 2014 12 30 Bolaamphiphiles: A Pharmaceutical Review 483 491 10.5681/apb.2014.072 EN Mayur Fariya Ankitkumar Jain Vivek Dhawan Sanket Shah Mangal S. Nagarsenker REVIEW 10.5681/apb.2014.072 2014 05 18 The field of drug discovery is ever growing and excipients play a major role in it. A novel class of amphiphiles has been discussed in the review. The review focuses on natural as well as synthetic bolaamphiphiles, their chemical structures and importantly, their ability to self assemble rendering them of great use to pharmaceutical industry. Recent reports on their ability to be used in fabrication of suitable nanosized carriers for drug as well as genes to target site, has been discussed substantially to understand the potential of bolaamphiphiles in field of drug delivery.