Tabriz University of Medical Sciences Advanced Pharmaceutical Bulletin 2228-5881 3 1 2013 06 30 Synthesis and Antimicrobial Evaluation of Certain Novel Thiazoles 227 230 10.5681/apb.2013.037 EN Meesaraganda Sreedevi Aluru Raghavendra Guru Prasad Yadati Narasimha Spoorthy Lakshmana Rao Krishna Rao Ravindranath Journal Article 10.5681/apb.2013.037 2012 11 25 Purpose: This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. Methods: The novel compounds synthesized were characterized by elemental analysis, IR and 1HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. Results: The compound p-t showed more antibacterial activity than that of the standard. p-hp and p-as showed considerable antibacterial activity. p-t demonstrated higher antifungal activity than that of the standard while p-hp and p-as showed considerable antifungal activity. Conclusion: The antimicrobial activity studies were conducted on certain selected bacteria and fungi. In each case antimicrobial activity of the compounds was compared with that of standards. p-t, p-hp, p-np, p-cp, p-ts and p-as showed considerable antimicrobial activity.