Tabriz University of Medical Sciences Advanced Pharmaceutical Bulletin 2228-5881 10 3 2020 05 11 Medicinal Plants Extracts with Antiangiogenic Activity: Where Is the Link? 370 378 10.34172/apb.2020.045 EN Zohreh Hoseinkhani https://orcid.org/0000-0002-4052-1754 Fathemeh Norooznezhad Mohsen Rastegari-Pouyani Kamran Mansouri https://orcid.org/0000-0002-0314-8735 REVIEW 10.34172/apb.2020.045 2019 08 04 2019 12 29 Angiogenesis is a strictly controlled process defined as the formation of new blood vessels essential for certain physiologic and pathologic conditions where the latter includes tumor growth, development, and metastasis. Thus, inhibiting angiogenesis along with other anticancer strategies such as chemotherapy seems to be invaluable for reaching an optimal outcome in cancer patients. It has been shown that some natural plant-derived compounds are capable of preventing the formation of these new blood vessels in the tumor and also inhibit the proliferation and growth of the cancer cells. In this review, we intend to introduce plants with anti-angiogenic properties and discuss their related features.