Mehran Alavi
1*, Naser Karimi
1, Mohsen Safaei
11 Department of nanobiotecnology, 67149 Baghabrisham, Razi University, Kermanshah, Iran.
Abstract
Liposomes, due to their
various forms, require further exploration. These structures can deliver both
hydrophilic and hydrophobic drugs for cancer, antibacterial, antifungal,
immunomodulation, diagnostics, ophtalmica, vaccines, enzymes and genetic
elements. Preparation of liposomes results in different properties for these
systems. In addition, based on preparation
methods, liposomes types can be unilamellar, multilamellar and giant
unilamellar; however, there are many factors and difficulties that affect the
development of liposome drug delivery structure. In the present review, we
discuss some problems that impact drug delivery by liposomes. In addition, we
discuss a new generation of liposomes, which is utilized for decreasing the
limitation of the conventional liposomes.