Adv Pharm Bull. 2017;7(1): 3-9.
doi: 10.15171/apb.2017.002
PMID: 28507932
PMCID: PMC5426731
Scopus ID: 85017542838
  Abstract View: 2437
  PDF Download: 2113


Application of Various Types of Liposomes in Drug Delivery Systems

Mehran Alavi 1*, Naser Karimi 1, Mohsen Safaei 1

1 Department of nanobiotecnology, 67149 Baghabrisham, Razi University, Kermanshah, Iran.


Liposomes, due to their various forms, require further exploration. These structures can deliver both hydrophilic and hydrophobic drugs for cancer, antibacterial, antifungal, immunomodulation, diagnostics, ophtalmica, vaccines, enzymes and genetic elements. Preparation of liposomes results in different properties for these systems. In addition, based on preparation methods, liposomes types can be unilamellar, multilamellar and giant unilamellar; however, there are many factors and difficulties that affect the development of liposome drug delivery structure. In the present review, we discuss some problems that impact drug delivery by liposomes. In addition, we discuss a new generation of liposomes, which is utilized for decreasing the limitation of the conventional liposomes.
Keywords: Liposomes, Hydrophobic drugs, Phospholipid, Drug delivery system
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Submitted: 18 Aug 2016
Revision: 17 Feb 2017
Accepted: 22 Feb 2017
ePublished: 13 Apr 2017
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