Logo-apb
Adv Pharm Bull. 2021;11(2): 248-260.
doi: 10.34172/apb.2021.030
PMID: 33880346
PMCID: PMC8046402
Scopus ID: 85103153097
  Abstract View: 1472
  PDF Download: 717
  Full Text View: 359

Review Article

Localized Delivery of Drugs through Medical Textiles for Treatment of Burns: A Perspective Approach

Ruchi Tiwari 1* ORCID logo, Gaurav Tiwari 1 ORCID logo, Akanksha Lahiri 1, Vadivelan R 2, Awani K Rai 1

1 Department of Pharmacy, Pranveer Singh Institute of Technology, Kalpi Road, Bhauti, Kanpur-208020, India.
2 Department of Pharmacology, JSS College of Pharmacy, Ooty-643001, India.
*Corresponding Author: *Corresponding Author: Ruchi Tiwari, Tel: +91-9369047641, Email: , Email: dr.ruchitiwari@psit.in

Abstract

The topical delivery offers numerous benefits, such as the ability to deliver drugs specifically on site selectively, prevents fluctuations in the levels of the drug, improved compliance, and improved self-medication capacity. Skin is the main route of the administration of the drug delivery system (DDS) and burns mainly cause skin damage. A burn is a kind of damage caused to skin and tissues by fire, ice, electrical energy, pollutants, friction, and radiation. There are three different types of burns, including superficial epidermis burns, partial-thickness dermis that stretch to the papillary and reticular dermis, and full-thickness burns that cover the dermis whole. The objective of the present review article is to focus on fabrication techniques of medical textiles, different types of polymers used for designing medicated textiles, skin burn conditions, and application of medicated textiles for treatment of burn along with other applications. Cream, ointment, and gel are the dosage forms used in burns. Intravenous fluids, wound care, assorted antibiotics, surgical and alternative medicines, burned creams and salami, dressings can be used to treat wounds. Nanofibers are nanometer-specific fibers that encapsulate drugs inside them and cure wounds. Nanofibers have all the properties that speed up wound healing. The properties are mechanical integrity, proper timing of wound addiction, temperature homeostasis facilitation and gas exchange, absorption of exudates. The nanofibers have been used in burn care and have been highly efficient and non-toxic.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 1473

Your browser does not support the canvas element.


PDF Download: 717

Your browser does not support the canvas element.


Full Text View: 359

Your browser does not support the canvas element.

Submitted: 18 May 2020
Revision: 12 Jul 2020
Accepted: 15 Jul 2020
ePublished: 15 Jul 2020
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)