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Adv Pharm Bull. 2023;13(3): 411-422.
doi: 10.34172/apb.2023.065
PMID: 37646053
PMCID: PMC10460808
  Abstract View: 790
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  Full Text View: 328

Review Article

Biosynthesis of Quantum Dots and Their Therapeutic Applications in the Diagnosis and Treatment of Cancer and SARS-CoV-2

Musa Moetasam Zorab 1 ORCID logo, Navid Mohammadjani 2, Morahem Ashengroph 2* ORCID logo, Mehran Alavi 2* ORCID logo

1 Department of Physics, University of Halabja, Kurdistan Region, Iraq.
2 Department of Biological Science, Faculty of Science, University of Kurdistan, Sanandaj, Kurdistan, Iran.
*Corresponding Authors: Morahem Ashengroph, Email: m.ashengroph@uok.ac.ir; Mehran Alavi, Email: mehranbio83@gmail.com

Abstract

Quantum dots (QDs) are semiconductor materials that range from 2 nm to 10 nm. These nanomaterials (NMs) are smaller and have more unique properties compared to conventional nanoparticles (NPs). One of the unique properties of QDs is their special optoelectronic properties, making it possible to apply these NMs in bioimaging. Different size and shape QDs, which are used in various fields such as bioimaging, biosensing, cancer therapy, and drug delivery, have so far been produced by chemical methods. However, chemical synthesis provides expensive routes and causes serious environmental and health issues. Therefore, various biological systems such as bacteria, fungi, yeasts, algae, and plants are considered as potent eco-friendly green nanofactories for the biosynthesis of QDs, which are both economic and environmentally safe. The review aims to provide a descriptive overview of the various microbial agents for the synthesis of QDs and their biomedical applications for the diagnosis and treatment of cancer and SARS-CoV-2.
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Submitted: 14 Apr 2022
Revision: 05 Dec 2022
Accepted: 05 Dec 2022
ePublished: 06 Dec 2022
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