Determination and Quantification of the Vinblastine Content in Purple, Red, and White Catharanthus Roseus Leaves Using RP-HPLC Method

Rohanizah Abdul Rahim ¹, Nor Hazwani Ahmad ¹, Khaldun Mohammad Al Azzam ^2,3 * , Ishak Mat ⁴

Cited by CrossRef: 9

1- Galal M, Saad A. Portable solid-state sensor for therapeutic monitoring of an antineoplastic drug; vinblastine in human plasma. RSC Adv. 2020;10(70):42699 [Crossref]

2- Kanwar H, Pandey S, Pandey R, Shukla S. VERSATILE APPROACHES FOR ANALYTICAL METHOD VALIDATION OF ANTICANCER DRUGS: A REVIEW. IND DRU. 2022;59(06):7 [Crossref]

3- Paul A, Acharya K, Chakraborty N. Biosynthesis, extraction, detection and pharmacological attributes of vinblastine and vincristine, two important chemotherapeutic alkaloids of Catharanthus roseus (L.) G. Don: A review. South African Journal of Botany. 2023;161:365 [Crossref]

4- Liu Q, Xia H, Xu Y, Cheng Y, Cheng Z. Investigation on the Preparation, Characteristics, and Controlled Release Model of Paeonol-Loaded Liposome in Carbomer Hydrogel. CDD. 2020;17(2):159 [Crossref]

5- Kumar S, Singh B, Singh R. Catharanthus roseus (L.) G. Don: A review of its ethnobotany, phytochemistry, ethnopharmacology and toxicities. Journal of Ethnopharmacology. 2022;284:114647 [Crossref]

6- Arulvendhan V, Saravana Bhavan P, Rajaganesh R. Molecular Identification and Phytochemical Analysis and Bioactivity Assessment of Catharanthus roseus Leaf Extract: Exploring Antioxidant Potential and Antimicrobial Activities. Appl Biochem Biotechnol. 2024;196(11):7614 [Crossref]

7- Al Azzam K, Al‐Areer N, Al Omari R, Al‐Deeb I, Bounoua N, Negim E, Al‐Samydai A, Aboalroub A, Said R. Assessment of the anticancer potential of certain phenolic and flavonoid components in ginger capsules using colorectal cancer cell lines coupled with quantitative analysis. Biomedical Chromatography. 2024;38(10) [Crossref]

8- Lanjar S, Solangi A, Batool N, Khand N, Kamboh M, Malah A, Buledi J, Khan M. Strategic electrochemical oxidation of vinblastin sulfate (an anticancer drug)viaPVP-functionalized strontium oxide nanoparticles. RSC Adv. 2024;14(43):31387 [Crossref]

9- Chen Y, Zhang H, Zhang M, Zhang W, Ou Z, Peng Z, Fu C, Zhao C, Yu L. Salicylic Acid-Responsive Factor TcWRKY33 Positively Regulates Taxol Biosynthesis in Taxus chinensis in Direct and Indirect Ways. Front Plant Sci. 2021;12 [Crossref]