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Adv Pharm Bull. 2015;5(2): 195-199. doi: 10.15171/apb.2015.027
PMID: 26236657        PMCID: PMC4517074

Original Research

Ghrelin Administration Increases the Bax/Bcl-2 Gene Expression Ratio in the Heart of Chronic Hypoxic Rats

Mohammad Reza Aliparasti 1, Mohammad Reza Alipour 1, Shohreh Almasi 2, Hadi Feizi 3 *

Cited by CrossRef: 14


1- Mega O, Benneth B, Edesiri T, Rume R, Victor E, Rotu R, Oghenetega B, Agbonifo-Chijiokwu E, Kingsley N, Andrew U, Adebayo O. Possible mechanisms involved in the testicular-protective property of quercetin in rats exposed to endosulfan toxicity. Pesticide Biochemistry and Physiology. 2022;188:105224 [Crossref]
2- Li Y, Lin L, Wang Q. Correlation of expression levels of caspase-3 and Bcl-2 in alveolar lavage fluid in neonatal respiratory distress syndrome and prognosis. Exp Ther Med. 2018; [Crossref]
3- Do B, Nguyen T, Ho N, Le T, Hoang N, Doan C. Mitochondria-mediated Caspase-dependent and Caspase-independent apoptosis induced by aqueous extract from Moringa oleifera leaves in human melanoma cells. Mol Biol Rep. 2020;47(5):3675 [Crossref]
4- Sherif I, Sarhan O. Candesartan in a rat model of testicular toxicity: New insight on its protective mechanism. Exp Biol Med (Maywood). 2019;244(7):593 [Crossref]
5- Luo F, Wen Y, Zhao L, Su S, Zhao Y, Lei W, Li Z. Chlamydia trachomatis induces lncRNA MIAT upregulation to regulate mitochondria‐mediated host cell apoptosis and chlamydial development. J Cellular Molecular Medi. 2022;26(1):163 [Crossref]
6- Tabrizian K, Shahriari Z, Rezaee R, Jahantigh H, Bagheri G, Tsarouhas K, Docea A, Tsatsakis A, Hashemzaei M. Cardioprotective effects of insulin on carbon monoxide-induced toxicity in male rats. Hum Exp Toxicol. 2019;38(1):148 [Crossref]
7- El-Beltagy A, Bakr S, Mekhaimer S, Ghanem N, Attaallah A. Zinc-nanoparticles alleviate the ovarian damage induced by bacterial lipopolysaccharide (LPS) in pregnant rats and their fetuses. Histochem Cell Biol. 2023;160(5):453 [Crossref]
8- Dziegala M, Kasztura M, Kobak K, Bania J, Banasiak W, Ponikowski P, Jankowska E. Influence of the availability of iron during hypoxia on the genes associated with apoptotic activity and local iron metabolism in rat H9C2 cardiomyocytes and L6G8C5 skeletal myocytes. 2016;14(4):3969 [Crossref]
9- Kobak K, Kasztura M, Dziegala M, Bania J, Kapuśniak V, Banasiak W, Ponikowski P, Jankowska E. Iron limitation promotes the atrophy of skeletal myocytes, whereas iron supplementation prevents this process in the hypoxic conditions. Int J Mol Med. 2018; [Crossref]
10- Nourmohammadi K, Babaei-Balderlou F, Abtahi-Foroushani S. Dopamine D2 Receptor Antagonist Alters the Testosterone Release and Kisspeptin/GPR54 Signaling in Food-Restricted Rats. Iran J Sci Technol Trans Sci. 2021;45(6):1879 [Crossref]
11- Alam R, Imam T, Abo-Elmaaty A, Arisha A. Amelioration of fenitrothion induced oxidative DNA damage and inactivation of caspase-3 in the brain and spleen tissues of male rats by N-acetylcysteine. Life Sciences. 2019;231:116534 [Crossref]
12- Li X, Cheng S, Wu Y, Ying J, Wang C, Wen T, Bai X, Ji W, Wang D, Ruan D. Functional self‐assembled peptide scaffold inhibits tumor necrosis factor‐alpha‐induced inflammation and apoptosis in nucleus pulposus cells by suppressing nuclear factor‐κB signaling. J Biomedical Materials Res. 2018;106(4):1082 [Crossref]
13- Bogomolovas J, Feng W, Yu M, Huang S, Zhang L, Trexler C, Gu Y, Spinozzi S, Chen J. Atypical ALPK2 kinase is not essential for cardiac development and function. American Journal of Physiology-Heart and Circulatory Physiology. 2020;318(6):H1509 [Crossref]
14- El-Magd M, Abdo W, El-Maddaway M, Nasr N, Gaber R, El-Shetry E, Saleh A, Alzahrani F, Abdelhady D. High doses of S-methylcysteine cause hypoxia-induced cardiomyocyte apoptosis accompanied by engulfment of mitochondaria by nucleus. Biomedicine & Pharmacotherapy. 2017;94:589 [Crossref]