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Adv Pharm Bull. 2017;7(4): 579-584. doi: 10.15171/apb.2017.069
PMID: 29399547        PMCID: PMC5788212

Research Article

Caffeine Neuroprotective Mechanism Against β-Amyloid Neurotoxicity in SHSY5Y Cell Line: Involvement of Adenosine, Ryanodine, and N-Methyl-D-Aspartate Receptors

Mojtaba Keshavarz 1 * , Majid Reza Farrokhi 1, Atena Amiri 1

Cited by CrossRef: 7


1- Gupta S, Dasmahapatra A. Caffeine destabilizes preformed Aβ protofilaments: insights from all atom molecular dynamics simulations. Phys Chem Chem Phys. 2019;21(39):22067 [Crossref]
2- 蒋 单. Advances in Sleep Induction by Adenosine Activation of A1 and A2A Receptors. ACM. 2023;13(02):2083 [Crossref]
3- Londzin P, Zamora M, Kąkol B, Taborek A, Folwarczna J. Potential of Caffeine in Alzheimer’s Disease—A Review of Experimental Studies. Nutrients. 2021;13(2):537 [Crossref]
4- Castillo C, Ballesteros-Yáñez I, León-Navarro D, Albasanz J, Martín M. Early Effects of the Soluble Amyloid β25-35 Peptide in Rat Cortical Neurons: Modulation of Signal Transduction Mediated by Adenosine and Group I Metabotropic Glutamate Receptors. IJMS. 2021;22(12):6577 [Crossref]
5- Gomaa A, Farghaly H, Ahmed A, El-Mokhtar M, Hemida F. Advancing combination treatment with cilostazol and caffeine for Alzheimer's disease in high fat-high fructose-STZ induced model of amnesia. European Journal of Pharmacology. 2022;921:174873 [Crossref]
6- Jawad M, Uthirapathy S, Altalbawy F, Oghenemaro E, Rizaev J, Lal M, Eldesoqui M, Sharma N, Pramanik A, AL-Hamairy A. Examining the role of antioxidant supplementation in mitigating oxidative stress markers in Alzheimer’s disease: a comprehensive review. Inflammopharmacol. 2024; [Crossref]
7- Pritam P, Deka R, Bhardwaj A, Srivastava R, Kumar D, Jha A, Jha N, Villa C, Jha S. Antioxidants in Alzheimer’s Disease: Current Therapeutic Significance and Future Prospects. Biology. 2022;11(2):212 [Crossref]
8- Badshah H, Ikram M, Ali W, Ahmad S, Hahm J, Kim M. Caffeine May Abrogate LPS-Induced Oxidative Stress and Neuroinflammation by Regulating Nrf2/TLR4 in Adult Mouse Brains. Biomolecules. 2019;9(11):719 [Crossref]