Adv Pharm Bull. 2015;5(3): 351-359. doi: 10.15171/apb.2015.049
PMID: 26504757        PMCID: PMC4616902

Original Research

Doxorubicin Changes Bax /Bcl-xL Ratio, Caspase-8 and 9 in Breast Cancer Cells


Cited by CrossRef: 16


1- Kumari S, Badana A, Mohan G, Shailender Naik G, Malla R. Synergistic effects of coralyne and paclitaxel on cell migration and proliferation of breast cancer cells lines. Biomedicine & Pharmacotherapy. 2017;91:436 [Crossref]
2- Tupal A, Sabzichi M, Ramezani F, Kouhsoltani M, Hamishehkar H. Dermal delivery of doxorubicin-loaded solid lipid nanoparticles for the treatment of skin cancer. Journal of Microencapsulation. 2016;33(4):372 [Crossref]
3- Zhang Z, Lin G, Yan Y, Li X, Hu Y, Wang J, Yin B, Wu Y, Li Z, Yang X. Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells. Oncogene. 2018;37(25):3456 [Crossref]
4- Jabbari N, Zarei L, Esmaeili Govarchin Galeh H, Mansori Motlagh B. Assessment of synergistic effect of combining hyperthermia with irradiation and calcium carbonate nanoparticles on proliferation of human breast adenocarcinoma cell line (MCF-7 cells). Artificial Cells, Nanomedicine, and Biotechnology. 2018;46(sup2):364 [Crossref]
5- Hallajian F, Ghasmi M, Abedi S, Behzadi R, Hayati E, Sadeghzadeh N, Rezazadeh F, Karimi H. Evaluation of the Effect of Resveratrol and Doxorubicin on 99mTc-MIBI Uptake in Breast Cancer Cell Xenografts in Mice. Cancer Biotherapy and Radiopharmaceuticals. 2018;33(9):403 [Crossref]
6- Sampson V, Vetter N, Kamara D, Collier A, Gresh R, Kolb E, Loeb D. Vorinostat Enhances Cytotoxicity of SN-38 and Temozolomide in Ewing Sarcoma Cells and Activates STAT3/AKT/MAPK Pathways. PLoS ONE. 2015;10(11):e0142704 [Crossref]
7- du Z. BAX, a novel cell pro-apoptotic protein, involved in hemocytes early antiviral immune response in fresh water crayfish, Procambarus clarkii. Fish & Shellfish Immunology. 2016;55:384 [Crossref]
8- Sesarman A, Tefas L, Sylvester B, Licarete E, Rauca V, Luput L, Patras L, Porav S, Banciu M, Porfire A. Co-delivery of curcumin and doxorubicin in PEGylated liposomes favored the antineoplastic C26 murine colon carcinoma microenvironment. Drug Deliv and Transl Res. 2019;9(1):260 [Crossref]
9- Chu B, Peng F, Wang H, Su Y, He Y. Synergistic effects between silicon nanowires and doxorubicin at non-toxic doses lead to high-efficacy destruction of cancer cells. J Mater Chem B. 2018;6(45):7378 [Crossref]
10- Guerriero E, Sorice A, Capone F, Storti G, Colonna G, Ciliberto G, Costantini S. Combining doxorubicin with a phenolic extract from flaxseed oil: Evaluation of the effect on two breast cancer cell lines. 2017;50(2):468 [Crossref]
11- Mi H, Wang X, Wang F, Li L, Zhu M, Wang N, Xiong Y, Gu Y. miR-381 induces sensitivity of breast cancer cells to doxorubicin by inactivation of MAPK signaling via FYN. European Journal of Pharmacology. 2018;839:66 [Crossref]
12- Kumari M, Purohit M, Patnaik S, Shukla Y, Kumar P, Gupta K. Curcumin loaded selenium nanoparticles synergize the anticancer potential of doxorubicin contained in self-assembled, cell receptor targeted nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics. 2018;130:185 [Crossref]
13- Ismail M, Negm A, Arafa R, Abdel-Latif E, El-Sayed W. Anticancer activity, dual prooxidant/antioxidant effect and apoptosis induction profile of new bichalcophene-5-carboxamidines. European Journal of Medicinal Chemistry. 2019;169:76 [Crossref]
14- Zununi Vahed S, Salehi R, Davaran S, Sharifi S. Liposome-based drug co-delivery systems in cancer cells. Materials Science and Engineering: C. 2017;71:1327 [Crossref]
15- Retracted : Bisindole-oxadiazole hybrids, T3P mediated® -synthesis and appraisal of their apoptotic, antimetastatic and computational Bcl-2 binding potential. J Biochem Mol Toxicol. 2017;31(11):e21962 [Crossref]
16- de Mello L, Souza G, Winter E, Silva A, Pittella F, Creczynski-Pasa T. Knockdown of antiapoptotic genes in breast cancer cells by siRNA loaded into hybrid nanoparticles. Nanotechnology. 2017;28(17):175101 [Crossref]
17- Jabłońska-Trypuć A, Świderski G, Krętowski R, Lewandowski W. Newly Synthesized Doxorubicin Complexes with Selected Metals—Synthesis, Structure and Anti-Breast Cancer Activity. Molecules. 2017;22(7):1106 [Crossref]
18- Kim J, Lee D, Na Y, Kim B, Jeong Y, Lee S, Kang S, Joung S, Lee S, Oh S, Min B. Iron chelator-induced apoptosis via the ER stress pathway in gastric cancer cells. Tumor Biol. 2016;37(7):9709 [Crossref]
19- Ashour F, Awwad M, Sharawy H, Kamal M. Estrogen receptor positive breast tumors resist chemotherapy by the overexpression of P53 in Cancer Stem Cells. Journal of the Egyptian National Cancer Institute. 2018;30(2):45 [Crossref]
20- QUISBERT-VALENZUELA E, CALAF G. Apoptotic effect of noscapine in breast cancer cell lines. 2016;48(6):2666 [Crossref]
21- Zununi Vahed S, Barzegari A, Rahbar Saadat Y, Goreyshi A, Omidi Y. Leuconostoc mesenteroides-derived anticancer pharmaceuticals hinder inflammation and cell survival in colon cancer cells by modulating NF-κB/AKT/PTEN/MAPK pathways. Biomedicine & Pharmacotherapy. 2017;94:1094 [Crossref]
22- Zununi Vahed S, Fathi N, Samiei M, Maleki Dizaj S, Sharifi S. Targeted cancer drug delivery with aptamer-functionalized polymeric nanoparticles. Journal of Drug Targeting. 2019;27(3):292 [Crossref]
23- Karimabad M, Mahmoodi M, Jafarzadeh A, Darehkordi A, Hajizadeh M, Khorramdelazad H, Falahati-pour S, Hassanshahi G. The novel Indole-3-formaldehyde (2-AITFEI-3-F) is involved in processes of apoptosis induction?. Life Sciences. 2017;181:31 [Crossref]
24- Cheemanapalli S, C.M. A, Pakala S, Chitta S. Design and screening of syringic acid analogues as BAX activators-An in silico approach to discover “BH3 mimetics”. Computational Biology and Chemistry. 2018;74:49 [Crossref]
25- Tavangar F, Sepehri H, Saghaeian Jazi M, Asadi J. Amphotericin B potentiates the anticancer activity of doxorubicin on the MCF-7 breast cancer cells. J Chem Biol. 2017;10(3):143 [Crossref]
26- Choupani J, Alivand M, M. Derakhshan S, Zaeifizadeh M, S. Khaniani M. Oleuropein inhibits migration ability through suppression of epithelial-mesenchymal transition and synergistically enhances doxorubicin-mediated apoptosis in MCF-7 cells. J Cell Physiol. 2018; [Crossref]
27- Xie L, Chen Y, Chen J, Zhang H, Liao Y, Zhou Y, Zhou L, Qing C. Anti-tumor effects and mechanism of GA-13315, a novel gibberellin derivative, in human lung adenocarcinoma: an in vitro and in vivo study. Cell Mol Biol Lett. 2019;24(1) [Crossref]
28- Pilco-Ferreto N, Calaf G. Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines. 2016;49(2):753 [Crossref]
29- Deihimi M, Moghbelinejad S, Najafipour R, Parivar K, Nassiri-Asl M. The Effects of Rutin on the Gene Expression of Dazl, Bcl2, and Caspase3 in Idarubicin-induced Testicular Damages in Mice. Iran Red Crescent Med J. 2017;19(4) [Crossref]
30- Shahi S, Zununi Vahed S, Fathi N, Sharifi S. Polymerase chain reaction (PCR)-based methods: Promising molecular tools in dentistry. International Journal of Biological Macromolecules. 2018;117:983 [Crossref]

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eISSN: 2251-7308 
pISSN: 2228-5881 
Freq.: Quarterly

 

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