Investigating Effect of Rapamycin and Metformin on Angiogenesis in Hepatocellular Carcinoma Cell Line

Mandana Rastegar ¹, Haji-Amin Marjani ¹, Yaghoub Yazdani ¹, Majid Shahbazi ¹, Masoud Golalipour ¹ * , Touraj Farazmandfar ¹ *

Cited by CrossRef: 8

1- Wang G, Lin F, Wan Q, Wu J, Luo M. Mechanisms of action of metformin and its regulatory effect on microRNAs related to angiogenesis. Pharmacological Research. 2021;164:105390 [Crossref]

2- Sunagawa Y, Shimizu K, Katayama A, Funamoto M, Shimizu K, Nurmila S, Shimizu S, Miyazaki Y, Katanasaka Y, Hasegawa K, Morimoto T. Metformin suppresses phenylephrine-induced hypertrophic responses by inhibiting p300-HAT activity in cardiomyocytes. Journal of Pharmacological Sciences. 2021;147(2):169 [Crossref]

3- Kaushik A, Kumar A, Yu C, Kuo S, Liang S, Singh S, Wang X, Wang Y, Yen C, Dai X, Wei D, Pan C, Shiue Y. PCL–DOX microdroplets: an evaluation of the enhanced intracellular delivery of doxorubicin in metastatic cancer cells via in silico and in vitro approaches. New J Chem. 2019;43(31):12241 [Crossref]

4- Heinz S, Freyberger A, Lawrenz B, Schladt L, Schmuck G, Ellinger-Ziegelbauer H. Energy metabolism modulation by biguanides in comparison with rotenone in rat liver and heart. Arch Toxicol. 2019;93(9):2603 [Crossref]

5- Wang P, Sun S, Ma H, Sun S, Zhao D, Wang S, Liang X. Treating tumors with minimally invasive therapy: A review. Materials Science and Engineering: C. 2020;108:110198 [Crossref]

6- Cao W, Liu X, Zhang Y, Li A, Xie Y, Zhou S, Song L, Xu R, Ma Y, Cai S, Tang X, Chutipongtanate S. BEZ235 Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib by Inhibiting PI3K/AKT/mTOR and Inducing Autophagy. BioMed Research International. 2021;2021:1 [Crossref]

7- Tawfik S, Abdollah M, Elmazar M, El-Fawal H, Abdelnaser A. Effects of Metformin Combined With Antifolates on HepG2 Cell Metabolism and Cellular Proliferation. Front Oncol. 2022;12 [Crossref]

8- Chen G, Zhou Z, Jin J, Zhou Y, Liu Y, Wang W. CXCR4 is a prognostic marker that inhibits the invasion and migration of gastric cancer by regulating VEGF expression. Oncol Lett. 2021;22(2) [Crossref]