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Adv Pharm Bull. 2016;6(4): 551-561. doi: 10.15171/apb.2016.069

PMID: 28101462 PMCID: PMC5241413

Research Article

Identification and Molecular Characterization of Genes Coding Pharmaceutically Important Enzymes from Halo-Thermo Tolerant Bacillus

Azam Safary ^1,2, Rezvan Moniri ^1,3 * , Maryam Hamzeh-Mivehroud ^2,4, Siavoush Dastmalchi ^2,4 *

Cited by CrossRef: 13

1- Akbarzadeh Khiavi M, Safary A, Aghanejad A, Barar J, Rasta S, Golchin A, Omidi Y, Somi M. Enzyme-conjugated gold nanoparticles for combined enzyme and photothermal therapy of colon cancer cells. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2019;572:333 [Crossref]

2- Akbarzadeh Khiavi M, Safary A, Somi M. Recent advances in targeted therapy of colorectal cancer: impacts of monoclonal antibodies nanoconjugates. Bioimpacts. 2019;9(3):123 [Crossref]

3- Safary A, Moghaddas-Sani H, Akbarzadeh-Khiavi M, Khabbazzi A, Rafi M, Omidi Y. Enzyme replacement combinational therapy: effective treatments for mucopolysaccharidoses. Expert Opinion on Biological Therapy. 2021;21(9):1181 [Crossref]

4- Olfati A, Akbarzadeh-Khiavi M, Safary A, Pourseif M, Adibkia K. Biological characterisation and computational conformation dynamics of putative L-glutaminase YLaM identified from Bacillus licheniformis . Molecular Simulation. 2024;50(16):1367 [Crossref]

5- Fathi M, Safary A, Barar J. Therapeutic impacts of enzyme-responsive smart nanobiosystems. Bioimpacts. 2019;10(1):1 [Crossref]

6- Toraby S, Farzi-Khajeh H, Rahbarnia L, Safary A, Akbarzadeh-Khiavi M. Immobilized recombinant laccase over PEGylated silica-coated magnetic nanoparticles for anti-inflammatory modulation in pro-monocytic model cell line. Process Biochemistry. 2024;146:56 [Crossref]

7- Simay S, Akbarzadeh-Khiavi M, Pourseif M, Barar J, Safary A, Omidi Y. Recombinant production and characterization of L-glutaminase (glsA) as a promiscuity therapeutic enzyme. Appl Microbiol Biotechnol. 2022;106(17):5511 [Crossref]

8- Akbarzadeh Khiavi M, Safary A, Barar J, Ajoolabady A, Somi M, Omidi Y. Multifunctional nanomedicines for targeting epidermal growth factor receptor in colorectal cancer. Cell Mol Life Sci. 2020;77(6):997 [Crossref]

9- Akbarzadeh-Khiavi M, Torabi M, Olfati A, Rahbarnia L, Safary A. Bio-nano scale modifications of melittin for improving therapeutic efficacy. Expert Opinion on Biological Therapy. 2022;22(7):895 [Crossref]

10- Guan Z, Luo Q, Wang H, Chen Y, Liao X. Bacterial laccases: promising biological green tools for industrial applications. Cell Mol Life Sci. 2018;75(19):3569 [Crossref]

11- Safary A, Moniri R, Hamzeh-Mivehroud M, Dastmalchi S. Highly efficient novel recombinant L-asparaginase with no glutaminase activity from a new halo-thermotolerant Bacillus strain. Bioimpacts. 2018;9(1):15 [Crossref]

12- Safary A, Akbarzadeh Khiavi M, Omidi Y, Rafi M. Targeted enzyme delivery systems in lysosomal disorders: an innovative form of therapy for mucopolysaccharidosis. Cell Mol Life Sci. 2019;76(17):3363 [Crossref]

13- Akbarzadeh Khiavi M, Safary A, Barar J, Farzi-Khajeh H, Barzegari A, Mousavi R, Somi M, Omidi Y. PEGylated gold nanoparticles-ribonuclease induced oxidative stress and apoptosis in colorectal cancer cells. Bioimpacts. 2019;10(1):27 [Crossref]