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Adv Pharm Bull. 2018;8(1): 21-27. doi: 10.15171/apb.2018.003
PMID: 29670835        PMCID: PMC5896392

Research Article

Preparation of the Potential Ocular Inserts by Electrospinning Method to Achieve the Prolong Release Profile of Triamcinolone Acetonide

Shahla Mirzaeei 1,2 * , Kaveh Berenjian 3, Rasol Khazaei 3

Cited by CrossRef: 43


1- Zheng W, Hao Y, Wang D, Huang H, Guo F, Sun Z, Shen P, Sui K, Yuan C, Zhou Q. Preparation of triamcinolone acetonide-loaded chitosan/fucoidan hydrogel and its potential application as an oral mucosa patch. Carbohydrate Polymers. 2021;272:118493 [Crossref]
2- Grimaudo M, Concheiro A, Alvarez-Lorenzo C. Crosslinked Hyaluronan Electrospun Nanofibers for Ferulic Acid Ocular Delivery. Pharmaceutics. 2020;12(3):274 [Crossref]
3- Bayat F, Hashtrodylar Y, Karimi H, Mehryab F, Haeri A. A precise look at electrospinning parameters in fabricating the polymeric nanofibers: a review on synthetic and natural polymers. J Pharm Investig. 2024;54(6):699 [Crossref]
4- Kurakula M, Koteswara Rao G. Moving polyvinyl pyrrolidone electrospun nanofibers and bioprinted scaffolds toward multidisciplinary biomedical applications. European Polymer Journal. 2020;136:109919 [Crossref]
5- Tapia-Hernández J, Del-Toro-Sánchez C, Cinco-Moroyoqui F, Juárez-Onofre J, Ruiz-Cruz S, Carvajal-Millan E, López-Ahumada G, Castro-Enriquez D, Barreras-Urbina C, Rodríguez-Felix F. Prolamins from cereal by-products: Classification, extraction, characterization and its applications in micro- and nanofabrication. Trends in Food Science & Technology. 2019;90:111 [Crossref]
6- Qureshi J, Iqbal F, Hussain F, Ijaz H, Aamir M, Afzal M. Fabrication and evaluation of Olopatadine hydrochloride ocular inserts. Journal of Plastic Film & Sheeting. 2020;36(3):243 [Crossref]
7- Omer S, Zelkó R. A Systematic Review of Drug-Loaded Electrospun Nanofiber-Based Ophthalmic Inserts. Pharmaceutics. 2021;13(10):1637 [Crossref]
8- Priya S, Batra U, R.N. S, Sharma S, Chaurasiya A, Singhvi G. Polysaccharide-based nanofibers for pharmaceutical and biomedical applications: A review. International Journal of Biological Macromolecules. 2022;218:209 [Crossref]
9- Popov Pereira da Cunha M, Caracciolo P, Abraham G. Latest advances in electrospun plant-derived protein scaffolds for biomedical applications. Current Opinion in Biomedical Engineering. 2021;18:100243 [Crossref]
10- Mirzaeei S, Mansurian M, Asare-Addo K, Nokhodchi A. Metronidazole- and Amoxicillin-Loaded PLGA and PCL Nanofibers as Potential Drug Delivery Systems for the Treatment of Periodontitis: In Vitro and In Vivo Evaluations. Biomedicines. 2021;9(8):975 [Crossref]
11- Uzel E, Durgun M, Esentürk-Güzel İ, Güngör S, Özsoy Y. Nanofibers in Ocular Drug Targeting and Tissue Engineering: Their Importance, Advantages, Advances, and Future Perspectives. Pharmaceutics. 2023;15(4):1062 [Crossref]
12- Andreadis I, Karavasili C, Thomas A, Komnenou A, Tzimtzimis M, Tzetzis D, Andreadis D, Bouropoulos N, Fatouros D. In Situ Gelling Electrospun Ocular Films Sustain the Intraocular Pressure-Lowering Effect of Timolol Maleate: In Vitro, Ex Vivo, and Pharmacodynamic Assessment. Mol Pharmaceutics. 2022;19(1):274 [Crossref]
13- Tawfik E, Alshamsan A, Abul Kalam M, Raish M, Alkholief M, Stapleton P, Harvey K, Craig D, Barker S. In vitro and in vivo biological assessment of dual drug-loaded coaxial nanofibers for the treatment of corneal abrasion. International Journal of Pharmaceutics. 2021;604:120732 [Crossref]
14- Yu H, Wu W, Lin X, Feng Y. Polysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective. Front Bioeng Biotechnol. 2020;8 [Crossref]
15- Ahmed S, Amin M, Sayed S. Ocular Drug Delivery: a Comprehensive Review. AAPS PharmSciTech. 2023;24(2) [Crossref]
16- de Farias B, Sant'Anna Cadaval Junior T, de Almeida Pinto L. Chitosan-functionalized nanofibers: A comprehensive review on challenges and prospects for food applications. International Journal of Biological Macromolecules. 2019;123:210 [Crossref]
17- Tawfik E, Craig D, Barker S. Dual drug-loaded coaxial nanofibers for the treatment of corneal abrasion. International Journal of Pharmaceutics. 2020;581:119296 [Crossref]
18- Issa T, Sayari F, Ghalla H, Benhamada L. Synthesis, crystal structure, DFT calculations and molecular docking of l-pyroglutamic acid. Journal of Molecular Structure. 2019;1178:436 [Crossref]
19- Mehrandish S, Mohammadi G, Mirzaeei S. Preparation and functional evaluation of electrospun polymeric nanofibers as a new system for sustained topical ocular delivery of itraconazole. Pharmaceutical Development and Technology. 2022;27(1):25 [Crossref]
20- Omer S, Nagy N, Pinke B, Mészáros L, Kazsoki A, Zelkó R. Development and Evaluation of Different Electrospun Cysteamine-Loaded Nanofibrous Webs: A Promising Option for Treating a Rare Lysosomal Storage Disorder. Pharmaceutics. 2024;16(8):1052 [Crossref]
21- Mirzaeei S, Taghe S, Asare-Addo K, Nokhodchi A. Polyvinyl Alcohol/Chitosan Single-Layered and Polyvinyl Alcohol/Chitosan/Eudragit RL100 Multi-layered Electrospun Nanofibers as an Ocular Matrix for the Controlled Release of Ofloxacin: an In Vitro and In Vivo Evaluation. AAPS PharmSciTech. 2021;22(5) [Crossref]
22- Doostmohammadi M, Forootanfar H, Ramakrishna S. Regenerative medicine and drug delivery: Progress via electrospun biomaterials. Materials Science and Engineering: C. 2020;109:110521 [Crossref]
23- Allyn M, Luo R, Hellwarth E, Swindle-Reilly K. Considerations for Polymers Used in Ocular Drug Delivery. Front Med. 2022;8 [Crossref]
24- Chandra N, Gorantla S, Priya S, Singhvi G. Insight on updates in polysaccharides for ocular drug delivery. Carbohydrate Polymers. 2022;297:120014 [Crossref]
25- Zamboulis A, Nanaki S, Michailidou G, Koumentakou I, Lazaridou M, Ainali N, Xanthopoulou E, Bikiaris D. Chitosan and its Derivatives for Ocular Delivery Formulations: Recent Advances and Developments. Polymers. 2020;12(7):1519 [Crossref]
26- Sakpal D, Gharat S, Momin M. Recent advancements in polymeric nanofibers for ophthalmic drug delivery and ophthalmic tissue engineering. Biomaterials Advances. 2022;141:213124 [Crossref]
27- Liu H, Gough C, Deng Q, Gu Z, Wang F, Hu X. Recent Advances in Electrospun Sustainable Composites for Biomedical, Environmental, Energy, and Packaging Applications. IJMS. 2020;21(11):4019 [Crossref]
28- Sangole S, Salave S, Rana D, Shah S, Medhe T, Benival D. Electrospun Nanofiber Composite for Levofloxacin in Ocular Drug Delivery. PNT. 2022;10(5):393 [Crossref]
29- Chu K, Zhu Y, Lu G, Huang S, Yang C, Zheng J, Chen J, Ban J, Jia H, Lu Z. Formation of Hydrophilic Nanofibers from Nanostructural Design in the Co-Encapsulation of Celecoxib through Electrospinning. Pharmaceutics. 2023;15(3):730 [Crossref]
30- Abdulhussain R, Adebisi A, Conway B, Asare-Addo K. Electrospun nanofibers: Exploring process parameters, polymer selection, and recent applications in pharmaceuticals and drug delivery. Journal of Drug Delivery Science and Technology. 2023;90:105156 [Crossref]
31- Garg P, Venuganti V, Roy A, Roy G. Novel drug delivery methods for the treatment of keratitis: moving away from surgical intervention. Expert Opinion on Drug Delivery. 2019;16(12):1381 [Crossref]
32- Mirzaeei S, Taghe S, Alany R, Nokhodchi A. Eudragit® L100/Polyvinyl Alcohol Nanoparticles Impregnated Mucoadhesive Films as Ocular Inserts for Controlled Delivery of Erythromycin: Development, Characterization and In Vivo Evaluation. Biomedicines. 2022;10(8):1917 [Crossref]
33- Mohammadi G, Mirzaeei S, Taghe S, Mohammadi P. Preparation and Evaluation of Eudragit® L100 Nanoparticles LoadedImpregnated with KT Tromethamine Loaded PVA -HEC Insertions forOphthalmic Drug Delivery. Adv Pharm Bull. 2019;9(4):593 [Crossref]
34- Sahu D, Rath G, Gupta G. Addressing ocular drug delivery challenges with solid nanofiber variants and supramolecular nanofibrous gel composite. Journal of Drug Delivery Science and Technology. 2024;94:105476 [Crossref]
35- Kobryń J, Raszewski B, Zięba T, Musiał W. Modified Potato Starch as a Potential Retardant for Prolonged Release of Lidocaine Hydrochloride from Methylcellulose Hydrophilic Gel. Pharmaceutics. 2023;15(2):387 [Crossref]
36- Iacob A, Lupascu F, Apotrosoaei M, Vasincu I, Tauser R, Lupascu D, Giusca S, Caruntu I, Profire L. Recent Biomedical Approaches for Chitosan Based Materials as Drug Delivery Nanocarriers. Pharmaceutics. 2021;13(4):587 [Crossref]
37- Shen L, Fang G, Tang B, Zhu Q. Enhanced topical corticosteroids delivery to the eye: A trade-off in strategy choice. Journal of Controlled Release. 2021;339:91 [Crossref]
38- Da Silva G, Lima T, Fernandes-Cunha G, Oréfice R, Da Silva-Cunha A, Zhao M, Behar-Cohen F. Ocular biocompatibility of dexamethasone acetate loaded poly(ɛ-caprolactone) nanofibers. European Journal of Pharmaceutics and Biopharmaceutics. 2019;142:20 [Crossref]
39- Maulvi F, Shetty K, Desai D, Shah D, Willcox M. Recent advances in ophthalmic preparations: Ocular barriers, dosage forms and routes of administration. International Journal of Pharmaceutics. 2021;608:121105 [Crossref]
40- Mirzaeei S, Barfar D. Design and Development of Antibacterial/Anti-inflammatory Dual Drug-Loaded Nanofibrous Inserts for Ophthalmic Sustained Delivery of Gentamicin and Methylprednisolone: In Vitro Bioassay, Solvent, and Method Effects’ Evaluation. Adv Pharm Bull. 2022;12(3):531 [Crossref]