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Adv Pharm Bull. 2016;6(1): 75-81. doi: 10.15171/apb.2016.012
PMID: 27123421        PMCID: PMC4845545

Original Research

Comparative Evaluation of Dexmedetomidine and Magnesium Sulphate on Propofol Consumption, Haemodynamics and Postoperative Recovery in Spine Surgery: A Prospective, Randomized, Placebo Controlled, Double-blind Study

Vinit K. Srivastava 1 * , Abhishek Mishra 1, Sanjay Agrawal 2, Sanjay Kumar 3, Sunil Sharma 1, Raj Kumar 1

Cited by CrossRef: 9


1- Campos J, Bas J, Campos C, Mariscal G, Bas T, Bas P. Efficacy and Safety of Intravenous Magnesium Sulfate in Spinal Surgery: A Systematic Review and Meta-Analysis. JCM. 2024;13(11):3122 [Crossref]
2- Lang B, Zhang L, Lin Y, Zhang W, Li F, Chen S, Farag E. Comparison of effects and safety in providing controlled hypotension during surgery between dexmedetomidine and magnesium sulphate: A meta-analysis of randomized controlled trials. PLoS ONE. 2020;15(1):e0227410 [Crossref]
3- De Cassai A, Boscolo A, Geraldini F, Zarantonello F, Pettenuzzo T, Pasin L, Iuzzolino M, Rossini N, Pesenti E, Zecchino G, Sella N, Munari M, Navalesi P. Effect of dexmedetomidine on hemodynamic responses to tracheal intubation: A meta-analysis with meta-regression and trial sequential analysis.. Journal of Clinical Anesthesia. 2021;72:110287 [Crossref]
4- Wu S, Chen H. A prospective, randomised double-blind study on the anaesthetic effect of dexmedetomidine hydrochloride in brainstem tumour surgery. World J Surg Onc. 2019;17(1) [Crossref]
5- Yue L, Lin Z, Mu G, Sun H. Impact of intraoperative intravenous magnesium on spine surgery: A systematic review and meta-analysis of randomized controlled trials. eClinicalMedicine. 2022;43:101246 [Crossref]
6- Mahajan L, Kaur M, Gupta R, Aujla K, Singh A, Kaur A. Attenuation of the pressor responses to laryngoscopy and endotracheal intubation with intravenous dexmedetomidine versus magnesium sulphate under bispectral index-controlled anaesthesia: A placebo-controlled prospective randomised trial. Indian J Anaesth. 2018;62(5):337 [Crossref]
7- Lamperti M, Tufegdzic B, Avitsian R. Management of complex spine surgery. 2017;30(5):551 [Crossref]
8- Menshawi M, Fahim H. Dexmedetomidine versus magnesium sulfate as adjunct to general anesthesia in patients undergoing video-assisted thoracoscopy. Ain-Shams J Anesthesiol. 2022;14(1) [Crossref]
9- Tsaousi G, Pourzitaki C, Aloisio S, Bilotta F. Dexmedetomidine as a sedative and analgesic adjuvant in spine surgery: a systematic review and meta-analysis of randomized controlled trials. Eur J Clin Pharmacol. 2018;74(11):1377 [Crossref]