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Adv Pharm Bull. 2015;5(4): 491-495. doi: 10.15171/apb.2015.067
PMID: 26819921        PMCID: PMC4729346

Original Research

Effect of Buspirone, Fluoxetine and 8-OH-DPAT on Striatal Expression of Bax, Caspase-3 and Bcl-2 Proteins in 6-Hydroxydopamine-Induced Hemi-Parkinsonian Rats

Hamdollah Sharifi 1, Alireza Mohajjel Nayebi 2,3 * , Safar Farajnia 2, Rasool Haddadi 4

Cited by CrossRef: 12


1- Eyvari Brooshghalan S, Sabahi M, Ebadi S, Sadeghian Z, Mohajjel Nayebi A, Haddadi R. Silibinin chronic treatment in a rat model of Parkinson disease: A comprehensive in-vivo evaluation and in silico molecular modeling. European Journal of Pharmacology. 2023;941:175517 [Crossref]
2- Haddadi R, Nayebi A, Eyvari Brooshghalan S. RETRACTED: Silymarin prevents apoptosis through inhibiting the Bax/caspase-3 expression and suppresses toll like receptor-4 pathway in the SNc of 6-OHDA intoxicated rats. Biomedicine & Pharmacotherapy. 2018;104:127 [Crossref]
3- Jabbari A, Alani B, Arjmand A, Mazoochi T, Kheiripour N, Ardjmand A. Silymarin pretreatment protects against ethanol-induced memory impairment: Biochemical and histopathological evidence. Journal of Chemical Neuroanatomy. 2023;132:102310 [Crossref]
4- Yan L, Xu X, He Z, Wang S, Zhao L, Qiu J, Wang D, Gong Z, Qiu X, Huang H. Antidepressant-Like Effects and Cognitive Enhancement of Coadministration of Chaihu Shugan San and Fluoxetine: Dependent on the BDNF-ERK-CREB Signaling Pathway in the Hippocampus and Frontal Cortex. BioMed Research International. 2020;2020:1 [Crossref]
5- Zheng X, Wu J, Zhu Y, Chen S, Chen Z, Chen T, Huang Z, Wei J, Li Y, Lei W. A Comparative study for striatal-direct and -indirect pathway neurons to DA depletion-induced lesion in a PD rat model. Neurochemistry International. 2018;118:14 [Crossref]
6- Zhang Z, Luo X, Jiang L, Wu H, Tan Z. How do HCN channels play a part in Alzheimer's and Parkinson's disease?. Ageing Research Reviews. 2024;100:102436 [Crossref]
7- Li Y, Lu J, Bai F, Xiao Y, Guo Y, Dong Z. Ginsenoside Rg3 Suppresses Proliferation and Induces Apoptosis in Human Osteosarcoma. BioMed Research International. 2018;2018:1 [Crossref]
8- Ahmad J, Haider N, Khan M, Md S, Alhakamy N, Ghoneim M, Alshehri S, Sarim Imam S, Ahmad M, Mishra A. Novel therapeutic interventions for combating Parkinson’s disease and prospects of Nose-to-Brain drug delivery. Biochemical Pharmacology. 2022;195:114849 [Crossref]
9- Wang L, Yang Y, Chen L, He Z, Bi D, Zhang L, Xu Y, He J. Compound Dihuang Granule Inhibits Nigrostriatal Pathway Apoptosis in Parkinson’s Disease by Suppressing the JNK/AP-1 Pathway. Front Pharmacol. 2021;12 [Crossref]
10- Khan M, Haider N, Singh T, Bandopadhyay R, Ghoneim M, Alshehri S, Taha M, Ahmad J, Mishra A. Promising biomarkers and therapeutic targets for the management of Parkinson's disease: recent advancements and contemporary research. Metab Brain Dis. 2023;38(3):873 [Crossref]
11- Vaghef L, Farajdokht F, Erfani M, Majdi A, Sadigh-Eteghad S, Karimi P, Sandoghchian Shotorbani S, Seyedi Vafaee M, Mahmoudi J. Cerebrolysin attenuates ethanol-induced spatial memory impairments through inhibition of hippocampal oxidative stress and apoptotic cell death in rats. Alcohol. 2019;79:127 [Crossref]
12- Haddadi R, Poursina M, Zeraati F, Nadi F. Gastrodin microinjection suppresses 6-OHDA-induced motor impairments in parkinsonian rats: insights into oxidative balance and microglial activation in SNc. Inflammopharmacol. 2018;26(5):1305 [Crossref]