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Adv Pharm Bull. 2016;6(1): 57-64. doi: 10.15171/apb.2016.009
PMID: 27123418        PMCID: PMC4845537

Original Research

Aggregated Nanotransfersomal Dry Powder Inhalation of Itraconazole for Pulmonary Drug Delivery

Mehdi Hassanpour Aghdam 1, Saeed Ghanbarzadeh 2,3, Yousef Javadzadeh 4, Hamed Hamishehkar 3 *

Cited by CrossRef: 21


1- Ito K. Inhaled antifungal therapy: benefits, challenges, and clinical applications. Expert Opinion on Drug Delivery. 2022;19(7):755 [Crossref]
2- Salatin S, Lotfipour F, Jelvehgari M. A brief overview on nano-sized materials used in the topical treatment of skin and soft tissue bacterial infections. Expert Opinion on Drug Delivery. 2019;16(12):1313 [Crossref]
3- Ahmed S, Mansour M, Ishak R, Mortada N. Customizable resveratrol spray-dried micro-composites for inhalation as a promising contender for treatment of idiopathic pulmonary fibrosis. International Journal of Pharmaceutics. 2023;642:123117 [Crossref]
4- Rahimkhani S, Ghanbarzadeh S, Nokhodchi A, Hamishehkar H. An In Vitro Aerosolization Efficiency Comparison of Generic and Branded Salbutamol Metered Dose Inhalers. Pharm Sci. 2017;23(1):77 [Crossref]
5- Kimura G, Nakaoki T, Colley T, Rapeport G, Strong P, Ito K, Kizawa Y. In Vivo Biomarker Analysis of the Effects of Intranasally Dosed PC945, a Novel Antifungal Triazole, on Aspergillus fumigatus Infection in Immunocompromised Mice . Antimicrob Agents Chemother. 2017;61(9) [Crossref]
6- Joshi M, Prabhakar B. Development of respirable rifampicin loaded bovine serum albumin formulation for the treatment of pulmonary tuberculosis. Journal of Drug Delivery Science and Technology. 2021;61:102197 [Crossref]
7- Singh S, Verma D, Mirza M, Das A, dudeja M, Anwer M, Sultana Y, Talegaonkar S, Iqbal Z. Development and optimization of ketoconazole loaded nano-transfersomal gel for vaginal delivery using Box-Behnken design: In vitro , ex vivo characterization and antimicrobial evaluation. Journal of Drug Delivery Science and Technology. 2017;39:95 [Crossref]
8- Cheng S, Tan Z, Pandey M, Srichana T, Pichika M, Gorain B, Choudhury H. A Critical Review on Emerging Trends in Dry Powder Inhaler Formulation for the Treatment of Pulmonary Aspergillosis. Pharmaceutics. 2020;12(12):1161 [Crossref]
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10- S, Hafeez A, Usmani S, Izhar M. Transfersome, an ultra-deformable lipid-based drug nanocarrier: an updated review with therapeutic applications. Naunyn-Schmiedeberg's Arch Pharmacol. 2024;397(2):639 [Crossref]
11- Celi S, Fernández-García R, Afonso-Urich A, Ballesteros M, Healy A, Serrano D. Co-Delivery of a High Dose of Amphotericin B and Itraconazole by Means of a Dry Powder Inhaler Formulation for the Treatment of Severe Fungal Pulmonary Infections. Pharmaceutics. 2023;15(11):2601 [Crossref]
12- Ramadhan S, Al-Kinani K. Statistical Optimization and Characterization of Nimodipine Transferosomes. Al-Rafidain J Med Sci. 2024;7(1(Special)):S77 [Crossref]
13- Shetty N, Zhang Y, Park H, Zemlyanov D, Shah D, He A, Ahn P, Mutukuri T, Chan H, Zhou Q. Surface Composition and Aerosolization Stability of an Inhalable Combinational Powder Formulation Spray Dried Using a Three-Fluid Nozzle. Pharm Res. 2020;37(11) [Crossref]
14- Gaur P, Minocha S, Mishra R, Lal N, Lata K. Recent Advances in Development of Vesicular Carrier for Transdermal Drug Delivery: A Review. Jordan j pharm sci. 2024;17(1):1 [Crossref]
15- Rai S, Pandey V, Rai G. Transfersomes as versatile and flexible nano-vesicular carriers in skin cancer therapy: the state of the art. Nano Reviews & Experiments. 2017;8(1):1325708 [Crossref]
16- Lee W, Loo C, Ghadiri M, Leong C, Young P, Traini D. The potential to treat lung cancer via inhalation of repurposed drugs. Advanced Drug Delivery Reviews. 2018;133:107 [Crossref]
17- Guo Y, Yang Y, Xu Y, Meng Y, Ye J, Xia X, Liu Y. Deformable Nanovesicle-Loaded Gel for Buccal Insulin Delivery. Pharmaceutics. 2022;14(11):2262 [Crossref]
18- Abdou E, Kandil S, Morsi A, Sleem M. In-vitro and in-vivo respiratory deposition of a developed metered dose inhaler formulation of an anti-migraine drug. Drug Delivery. 2019;26(1):689 [Crossref]
19- Qu S, Zhao L, Zhu J, Wang C, Dai C, Guo H, Hao Z. Preparation and testing of cefquinome-loaded poly lactic-co-glycolic acid microspheres for lung targeting. Drug Delivery. 2017;24(1):745 [Crossref]
20- Almehmady A, Elsisi A. Development, optimization, and evaluation of tamsulosin nanotransfersomes to enhance its permeation and bioavailability. Journal of Drug Delivery Science and Technology. 2020;57:101667 [Crossref]