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EBSCOhost; CAS: DOAJ

Adv Pharm Bull. 2016;6(2): 257-260. doi: 10.15171/apb.2016.035

PMID: 27478789 PMCID: PMC4961985

Short Communication

The Effect of Spacer Morphology on the Aerosolization Performance of Metered-Dose Inhalers

Sepideh Momeni ^1,2, Ali Nokhodchi ³, Saeed Ghanbarzadeh ^4,5, Hamed Hamishehkar ⁵ *

Cited by CrossRef: 5

1- Leung S, Chiow A, Kwok P, Ukkonen A, Chan H. Effect of Spacers on the Bipolar Electrostatic Charge Properties of Metered Dose Inhaler Aerosols—A Case Study With Tilade®. Journal of Pharmaceutical Sciences. 2017;106(6):1553 [Crossref]

2- de Charras Y, Ramírez Rigo M, Bertin D. Aerosol deposition and emission from a United States Pharmacopeia‐induction port when using a pressurized metered‐dose inhaler with and without a valved holding chamber. Can J Chem Eng. 2024;102(8):2650 [Crossref]

3- Azimi S, Arzanpour S. Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber. 2024;146(4) [Crossref]

4- Alizadeh Bahmani A, Abdel-Aziz M, Hashimoto S, Bang C, Brandstetter S, Corcuera-Elosegui P, Franke A, Gorenjak M, Harner S, Kheiroddin P, López-Fernández L, Neerincx A, Pino-Yanes M, Potočnik U, Sardón-Prado O, Toncheva A, Wolff C, Kabesch M, Kraneveld A, Vijverberg S, Maitland-van der Zee A. Association of Corticosteroid Inhaler Type with Saliva Microbiome in Moderate-to-Severe Pediatric Asthma. Biomedicines. 2025;13(1):89 [Crossref]

5- Sobh A, Mohsen M, Abdelfattah A, Abdelrahim M, Mohamed B. Balancing efficacy and portability: comparative in vitro / in vivo evaluation of MDI PLUS® versus AeroChamber2go™ spacers for aerosol delivery . Journal of Asthma. 2025;:1 [Crossref]

6- Sayed O, Abdelrahim M, Laz N, Saeed H. Assessment of Emergency Spacers Versus Traditional Spacers, An In-Vitro Model for Aerosol Delivery. AAPS PharmSciTech. 2025;26(5) [Crossref]

7- Khalili S, Ghanbarzadeh S, Nokhodchi A, Hamishehkar H. The effect of different coating materials on the prevention of powder bounce in the next generation impactor. Res Pharma Sci. 2018;13(3):283 [Crossref]

8- Rahimkhani S, Ghanbarzadeh S, Nokhodchi A, Hamishehkar H. An In Vitro Aerosolization Efficiency Comparison of Generic and Branded Salbutamol Metered Dose Inhalers. Pharm Sci. 2017;23(1):77 [Crossref]

9- Kashikar R, Kotha A, Shrestha R, Channappanavar R, Chougule M. Formulation and In-Vitro Testing of Nebulized Camostat Mesylate Loaded Nanoliposomes for the Treatment of SARS-CoV- 2 Infection. AAPS PharmSciTech. 2025;26(5) [Crossref]