The Effect of Spacer Morphology on the Aerosolization Performance of Metered-Dose Inhalers

Sepideh Momeni ^1,2, Ali Nokhodchi ³, Saeed Ghanbarzadeh ^4,5, Hamed Hamishehkar ⁵ *

Cited by CrossRef: 5

1- Leung S, Chiow A, Kwok P, Ukkonen A, Chan H. Effect of Spacers on the Bipolar Electrostatic Charge Properties of Metered Dose Inhaler Aerosols—A Case Study With Tilade®. Journal of Pharmaceutical Sciences. 2017;106(6):1553 [Crossref]

2- de Charras Y, Ramírez Rigo M, Bertin D. Aerosol deposition and emission from a United States Pharmacopeia‐induction port when using a pressurized metered‐dose inhaler with and without a valved holding chamber. Can J Chem Eng. 2024;102(8):2650 [Crossref]

3- Azimi S, Arzanpour S. Enhancing Inhalation Drug Delivery: A Comparative Study and Design Optimization of a Novel Valved Holding Chamber. 2024;146(4) [Crossref]

4- Alizadeh Bahmani A, Abdel-Aziz M, Hashimoto S, Bang C, Brandstetter S, Corcuera-Elosegui P, Franke A, Gorenjak M, Harner S, Kheiroddin P, López-Fernández L, Neerincx A, Pino-Yanes M, Potočnik U, Sardón-Prado O, Toncheva A, Wolff C, Kabesch M, Kraneveld A, Vijverberg S, Maitland-van der Zee A. Association of Corticosteroid Inhaler Type with Saliva Microbiome in Moderate-to-Severe Pediatric Asthma. Biomedicines. 2025;13(1):89 [Crossref]

5- Khalili S, Ghanbarzadeh S, Nokhodchi A, Hamishehkar H. The effect of different coating materials on the prevention of powder bounce in the next generation impactor. Res Pharma Sci. 2018;13(3):283 [Crossref]

6- Rahimkhani S, Ghanbarzadeh S, Nokhodchi A, Hamishehkar H. An In Vitro Aerosolization Efficiency Comparison of Generic and Branded Salbutamol Metered Dose Inhalers. Pharm Sci. 2017;23(1):77 [Crossref]