Logo-apb
Adv Pharm Bull. 2016;6(1): 83-90. doi: 10.15171/apb.2016.013
PMID: 27123422        PMCID: PMC4845550

Original Research

Preparation and Characterization of Nanosuspension of Aprepitant by H96 Process

Sunethra Kalvakuntla 1, Mangesh Deshpande 2, Zenab Attari 1, Koteshwara Kunnatur B 1 *

Cited by CrossRef: 33


1- KOCA M, ÖZAKAR E, SEVİNÇ ÖZAKAR R. TRİİYODOANİLİN’İN SENTEZLENMESİ, NANOSÜSPANSİYONLARININ HAZIRLANMASI, İN VİTRO KARAKTERİZASYONU VE RADYOKONTRAST ÖZELLİKLERİNİN İNCELENMESİ. 2021;:9 [Crossref]
2- Salesa A, Esteban L, Barris C. Confinement of FRP concrete columns: Review of design guidelines and comparison with experimental results. materconstrucc. 2022;72(345):e274 [Crossref]
3- Gu C, Liu Z, Yuan X, Li W, Zu Y, Fu Y. Preparation of Vitexin Nanoparticles by Combining the Antisolvent Precipitation and High Pressure Homogenization Approaches Followed by Lyophilization for Dissolution Rate Enhancement. Molecules. 2017;22(11):2038 [Crossref]
4- Guan W, Ma Y, Ding S, Liu Y, Song Z, Liu X, Tang L, Wang Y. The technology for improving stability of nanosuspensions in drug delivery. J Nanopart Res. 2022;24(1) [Crossref]
5- Lee J, Sah H. Preparation of PLGA Nanoparticles by Milling Spongelike PLGA Microspheres. Pharmaceutics. 2022;14(8):1540 [Crossref]
6- Perween N, Alshehri S, Easwari T, Verma V, Faiyazuddin M, Alanazi A, Shakeel F. Investigating the Feasibility of Mefenamic Acid Nanosuspension for Pediatric Delivery: Preparation, Characterization, and Role of Excipients. Processes. 2021;9(4):574 [Crossref]
7- Hussain M, Rehan T, Goh K, Shah S, Khan A, Ming L, Shah N. Fabrication of a Double Core–Shell Particle-Based Magnetic Nanocomposite for Effective Adsorption-Controlled Release of Drugs. Polymers. 2022;14(13):2681 [Crossref]
8- Karakucuk A, Tort S. Preparation, characterization and antimicrobial activity evaluation of electrospun PCL nanofiber composites of resveratrol nanocrystals. Pharmaceutical Development and Technology. 2020;25(10):1216 [Crossref]
9- Jakubowska E, Lulek J. The application of freeze-drying as a production method of drug nanocrystals and solid dispersions – A review. Journal of Drug Delivery Science and Technology. 2021;62:102357 [Crossref]
10- Kakade P, Pathan Z, Gite S, Mirani A, Patravale V. Nanoparticle Engineering of Aprepitant Using Nano-by-Design (NbD) Approach. AAPS PharmSciTech. 2022;23(6) [Crossref]
11- Sakai-Kato K, Nanjo K, Takechi-Haraya Y, Goda Y, Okuda H, Izutsu K. Detailed Morphological Characterization of Nanocrystalline Active Ingredients in Solid Oral Dosage Forms Using Atomic Force Microscopy. AAPS PharmSciTech. 2019;20(2) [Crossref]
12- Reppas C, Kuentz M, Bauer-Brandl A, Carlert S, Dallmann A, Dietrich S, Dressman J, Ejskjaer L, Frechen S, Guidetti M, Holm R, Holzem F, Karlsson Ε, Kostewicz E, Panbachi S, Paulus F, Senniksen M, Stillhart C, Turner D, Vertzoni M, Vrenken P, Zöller L, Griffin B, O'Dwyer P. Leveraging the use of in vitro and computational methods to support the development of enabling oral drug products: An InPharma commentary. European Journal of Pharmaceutical Sciences. 2023;188:106505 [Crossref]
13- Nazlı H, Mesut B, Özsoy Y. In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility. Pharmaceuticals. 2021;14(11):1089 [Crossref]
14- Fujii M, Inoue M, Fukami T. Novel amino acid‐based surfactant for silicone emulsification and its application in hair care products: a promising alternative to quaternary ammonium cationic surfactants. Intern J of Cosmetic Sci. 2017;39(5):556 [Crossref]
15- Oyanna V, Clarke J. Mechanisms of intestinal pharmacokinetic natural product-drug interactions. Drug Metabolism Reviews. 2024;56(3):285 [Crossref]
16- Nagpal S, Kumari P, Saini K, Kakkar V. Pain Management with Topical Aceclofenac Nanosuspension In-Vitro/In- Vivo and Proof of Concept Studies. CDTH. 2022;17(4):289 [Crossref]
17- Kakade P, Gite S, Patravale V. Development of Atovaquone Nanosuspension: Quality by Design Approach. CDD. 2020;17(2):112 [Crossref]
18- Chogale M, Gite S, Patravale V. Comparison of media milling and microfluidization methods for engineering of nanocrystals: a case study. Drug Development and Industrial Pharmacy. 2020;46(11):1763 [Crossref]
19- Aguilar-Hernández G, López-Romero B, Nicolás-García M, Nolasco-González Y, García-Galindo H, Montalvo-González E. Nanosuspensions as carriers of active ingredients: Chemical composition, development methods, and their biological activities. Food Research International. 2023;174:113583 [Crossref]
20- Kaur J, Anwer M, Sartaj A, Panda B, Ali A, Zafar A, Kumar V, Gilani S, Kala C, Taleuzzaman M. ZnO Nanoparticles of Rubia cordifolia Extract Formulation Developed and Optimized with QbD Application, Considering Ex Vivo Skin Permeation, Antimicrobial and Antioxidant Properties. Molecules. 2022;27(4):1450 [Crossref]
21- Mohamed E, Dharani S, Khuroo T, Nutan M, Cook P, Arunagiri R, Khan M, Rahman Z. Oral Bioavailability Enhancement of Poorly Soluble Drug by Amorphous Solid Dispersion Using Sucrose Acetate Isobutyrate. AAPS PharmSciTech. 2024;25(7) [Crossref]
22- Xia Q, Shen J, Ding H, Liu S, Li F, Li F, Feng N. Intravenous nanocrystals: fabrication, solidification, in vivo fate, and applications for cancer therapy. Expert Opinion on Drug Delivery. 2023;20(11):1467 [Crossref]
23- Kamble S, Agrawal S, Cherumukkil S, Sharma V, Jasra R, Munshi P. Revisiting Zeta Potential, the Key Feature of Interfacial Phenomena, with Applications and Recent Advancements. ChemistrySelect. 2022;7(1) [Crossref]
24- Kral Ö, Ilbasmis-Tamer S, Han S, Tirnaksiz F. Development of Dermal Lidocaine Nanosuspension Formulation by the Wet Milling Method Using Experimental Design: In Vitro/In Vivo Evaluation. ACS Omega. 2024; [Crossref]
25- Tyler T, Schultz A, Venturini A, Giuliano C, Bernareggi A, Spezia R, Voisin D, Stella V. Challenges in the Development of Intravenous Neurokinin‐1 Receptor Antagonists: Results of a Safety and Pharmacokinetics Dose‐Finding, Phase 1 Study of Intravenous Fosnetupitant. Clinical Pharm in Drug Dev. 2022;11(12):1405 [Crossref]
26- Li J, Wang Z, Zhang H, Gao J, Zheng A. Progress in the development of stabilization strategies for nanocrystal preparations. Drug Delivery. 2021;28(1):19 [Crossref]
27- Najm M, Rawas-Qalaji M, Assar N, Yahia R, Hosary R, Ahmed I. Optimization, characterization and in vivo evaluation of mupirocin nanocrystals for topical administration. European Journal of Pharmaceutical Sciences. 2022;176:106251 [Crossref]
28- Ambrus R, Alshweiat A, Szabó-Révész P, Bartos C, Csóka I. Smartcrystals for Efficient Dissolution of Poorly Water-Soluble Meloxicam. Pharmaceutics. 2022;14(2):245 [Crossref]
29- Khanuja H, Awasthi R, Dureja H. Sorafenib tosylate-loaded nanosuspension: preparation, optimization, and in vitro cytotoxicity study against human HepG2 carcinoma cells . Journal of Chemotherapy. 2024;36(4):299 [Crossref]
30- Ding Y, Zhao T, Fang J, Song J, Dong H, Liu J, Li S, Zhao M. Recent developments in the use of nanocrystals to improve bioavailability of APIs. WIREs Nanomed Nanobiotechnol. 2024;16(2) [Crossref]
31- JADHAV S, DHAKAD P, GUPTA T, GILHOTRA R. FORMULATION DEVELOPMENT AND EVALUATION OF PALIPERIDONE NANOSUSPENSION FOR SOLUBILITY ENHANCEMENT. Int J App Pharm. 2024;:173 [Crossref]
32- Shaikh F, Patel M, Patel V, Patel A, Shinde G, Shelke S, Pathan I. Formulation and optimization of cilnidipine loaded nanosuspension for the enhancement of solubility, dissolution and bioavailability. Journal of Drug Delivery Science and Technology. 2022;69:103066 [Crossref]