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Adv Pharm Bull. 2016;6(2): 243-250. doi: 10.15171/apb.2016.033
PMID: 27478787        PMCID: PMC4961983

Research Article

Vitamin C for the Prevention of Postoperative Atrial Fibrillation after Cardiac Surgery: A Meta-Analysis

Evangelos Polymeropoulos 1 * , Pantelis Bagos 2, Maria Papadimitriou 3, Ioannis Rizos 4, Efstratios Patsouris 5, Ioannis Toumpoulis 6

Cited by CrossRef: 20


1- Hill A, Clasen K, Wendt S, Majoros Á, Stoppe C, Adhikari N, Heyland D, Benstoem C. Effects of Vitamin C on Organ Function in Cardiac Surgery Patients: A Systematic Review and Meta-Analysis. Nutrients. 2019;11(9):2103 [Crossref]
2- Putzu A, Daems A, Lopez-Delgado J, Giordano V, Landoni G. The Effect of Vitamin C on Clinical Outcome in Critically Ill Patients: A Systematic Review With Meta-Analysis of Randomized Controlled Trials*. 2019;47(6):774 [Crossref]
3- Sharma Y, Miller M, Shahi R, Doyle A, Horwood C, Hakendorf P, Thompson C. Vitamin C deficiency in Australian hospitalised patients: an observational study. Internal Medicine Journal. 2019;49(2):189 [Crossref]
4- Efird J, Jindal C, Kiser A, Akhter S, Crane P, Kypson A, Sverdlov A, Davies S, Kindell L, Anderson E. Increased risk of atrial fibrillation among patients undergoing coronary artery bypass graft surgery while receiving nitrates and antiplatelet agents. J Int Med Res. 2018;46(8):3183 [Crossref]
5- Hill A, Borgs C, Fitzner C, Stoppe C. Perioperative Vitamin C and E levels in Cardiac Surgery Patients and Their Clinical Significance. Nutrients. 2019;11(9):2157 [Crossref]
6- Toporcer T, Luczy J, Kolesár A, Ledecký M, Sabol F. The effect of surgical access for mitral valve surgery on incidence of atrial fibrillation and atrioventricular block. Cor Vasa. 2017;59(4):e381 [Crossref]
7- Hill A, Nesterova E, Lomivorotov V, Efremov S, Goetzenich A, Benstoem C, Zamyatin M, Chourdakis M, Heyland D, Stoppe C. Current Evidence about Nutrition Support in Cardiac Surgery Patients—What Do We Know?. Nutrients. 2018;10(5):597 [Crossref]
8- Nso N, Bookani K, Metzl M, Radparvar F. Role of inflammation in atrial fibrillation: A comprehensive review of current knowledge. Journal of Arrhythmia. 2021;37(1):1 [Crossref]
9- Hemilä H. Erroneus calculation of sample size in a vitamin C and atrial fibrillation trial. Journal of Cardiology. 2017;69(6):895 [Crossref]
10- Dresen E, Lee Z, Hill A, Notz Q, Patel J, Stoppe C. History of scurvy and use of vitamin C in critical illness: A narrative review. Nut in Clin Prac. 2023;38(1):46 [Crossref]
11- Polintan E, Monsalve R, Menghrajani R, Sirilan K, Nayak S, Abdelmaseeh P, Patarroyo-Aponte G, Lo K, Dani S. Combination prophylactic amiodarone with beta-blockers versus beta-blockers in atrial fibrillation after cardiac surgery: A systematic-review and meta-analysis. Heart & Lung. 2023;62:256 [Crossref]
12- Golder J, Bauer J, Barker L, Lemoh C, Gibson S, Davidson Z. Prevalence, risk factors, and clinical outcomes of vitamin C deficiency in adult hospitalized patients in high-income countries: a scoping review. 2024; [Crossref]
13- Ramanathan N, Tan E, Loh L, Soh B, Yap W. Tocotrienol is a cardioprotective agent against ageing-associated cardiovascular disease and its associated morbidities. Nutr Metab (Lond). 2018;15(1) [Crossref]
14- Hu X, Yuan L, Wang H, Li C, Cai J, Hu Y, Ma C. Efficacy and safety of vitamin C for atrial fibrillation after cardiac surgery: A meta-analysis with trial sequential analysis of randomized controlled trials. International Journal of Surgery. 2017;37:58 [Crossref]
15- Hill A, Wendt S, Benstoem C, Neubauer C, Meybohm P, Langlois P, Adhikari N, Heyland D, Stoppe C. Vitamin C to Improve Organ Dysfunction in Cardiac Surgery Patients—Review and Pragmatic Approach. Nutrients. 2018;10(8):974 [Crossref]
16- Hill A, Starchl C, Dresen E, Stoppe C, Amrein K. An update of the effects of vitamins D and C in critical illness. Front Med. 2023;9 [Crossref]
17- Hemilä H, Chalker E. Vitamin C Can Shorten the Length of Stay in the ICU: A Meta-Analysis. Nutrients. 2019;11(4):708 [Crossref]
18- Mauerhofer C, Grumet L, Schemmer P, Leber B, Stiegler P. Combating Ischemia-Reperfusion Injury with Micronutrients and Natural Compounds during Solid Organ Transplantation: Data of Clinical Trials and Lessons of Preclinical Findings. IJMS. 2021;22(19):10675 [Crossref]
19- Boriani G, Fauchier L, Aguinaga L, Beattie J, Blomstrom Lundqvist C, Cohen A, Dan G, Genovesi S, Israel C, Joung B, Kalarus Z, Lampert R, Malavasi V, Mansourati J, Mont L, Potpara T, Thornton A, Lip G, Gorenek B, Marin F, Dagres N, Ozcan E, Lenarczyk R, Crijns H, Guo Y, Proietti M, Sticherling C, Huang D, Daubert J, Pokorney S, Cabrera Ortega M, Chin A. European Heart Rhythm Association (EHRA) consensus document on management of arrhythmias and cardiac electronic devices in the critically ill and post-surgery patient, endorsed by Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Cardiac Arrhythmia Society of Southern Africa (CASSA), and Latin American Heart Rhythm Society (LAHRS). 2019;21(1):7 [Crossref]
20- Rodrigo R, González-Montero J, Sotomayor C. Novel Combined Antioxidant Strategy against Hypertension, Acute Myocardial Infarction and Postoperative Atrial Fibrillation. Biomedicines. 2021;9(6):620 [Crossref]
21- Shi R, Li Z, Chen D, Wu Q, Zhou X, Tie H. Sole and combined vitamin C supplementation can prevent postoperative atrial fibrillation after cardiac surgery: A systematic review and meta‐analysis of randomized controlled trials. Clinical Cardiology. 2018;41(6):871 [Crossref]