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EBSCOhost; CAS: DOAJ

Adv Pharm Bull. 2016;6(1): 137-141. doi: 10.15171/apb.2016.020

PMID: 27123429 PMCID: PMC4845542

Short Communication

Stability-Indicating HPLC Method for Simultaneous Determination of Chloramphenicol, Dexamethasone Sodium Phosphate and Tetrahydrozoline Hydrochloride in Ophthalmic Solution

Hashem AlAani ¹ * , Yasmin Alnukkary ²

Cited by CrossRef: 8

1- Eltanany B, El-Hadi H, Zaazaa H, Eissa M. Spectrophotometric Methods for the Determination of Chloramphenicol, Dexamethasone Sodium Phosphate, and Tetrahydrozoline HCl in their Pure and Ophthalmic Dosage Forms. J Appl Spectrosc. 2021;88(5):1081 [Crossref]

2- Kuang K, Chen Y, Li Y, Ji Y, Jia N. N-doped TiO2/Ti3C2-driven self-photocatalytic molecularly imprinted ECL sensor for sensitive and steady detection of dexamethasone. Biosensors and Bioelectronics. 2024;247:115914 [Crossref]

3- López-Cano J, López-Cano S, Andrés-Guerrero V, Tai H, Bravo-Osuna I, Molina-Martínez I, Wang W, Herrero-Vanrell R. Thermo-Responsive PLGA-PEG-PLGA Hydrogels as Novel Injectable Platforms for Neuroprotective Combined Therapies in the Treatment of Retinal Degenerative Diseases. Pharmaceutics. 2021;13(2):234 [Crossref]

4- Da Ruos J, Baldo M, Daniele S. Analytical Methods for the Determination of Major Drugs Used for the Treatment of COVID-19. A Review. Critical Reviews in Analytical Chemistry. 2023;53(8):1698 [Crossref]

5- Magdy M, Abdelfatah R, Abdelrahman M, Elsayed M. Feasible HPLC method for simultaneous determination of triple therapy prescribed for cancer patients with application to human plasma: Method’s greenness, whiteness, and blueness appraisal. Microchemical Journal. 2025;209:112731 [Crossref]

6- Lehner E, Trutschel M, Menzel M, Jacobs J, Kunert J, Scheffler J, Binder W, Schmelzer C, Plontke S, Liebau A, Mäder K. Enhancing drug release from PEG-PLGA implants: The role of Hydrophilic Dexamethasone Phosphate in modulating release kinetics and degradation behavior. European Journal of Pharmaceutical Sciences. 2025;209:107067 [Crossref]

7- Eissa M, Abd El-Hadi H, Zaazaa H, Eltanany B. Smart TLC–densitometric methods for determination of ophthalmic ternary mixture containing chloramphenicol in the presence of its synthetic precursor: Comparative eco-scaling for greenness assessment. JPC-J Planar Chromat. 2020;33(5):501 [Crossref]

8- Chen F, Wang L, Guo J, Shi X, Fang B. Simultaneous Determination of Dexamethasone, Ondansetron, Granisetron, Tropisetron, and Azasetron in Infusion Samples by HPLC with DAD Detection. Journal of Analytical Methods in Chemistry. 2017;2017:1 [Crossref]

9- Aljohar H, altoum G, Alkarni S, Alburaidi M, Alhabardi S. Quality assessment of some specific drug products beyond expiration dates in Saudi Arabia. Saudi Pharm J. 2025;33(3) [Crossref]

10- Miao Y, Xu J, Liu Y, Yang F, Zheng X, Xie W, Zhang Y. Comparative Evaluation of the Transdermal Permeation Effectiveness of Fu’s Cupping Therapy on Eight Different Types of Model Drugs. CDD. 2021;18(4):446 [Crossref]

11- Svalova T, Zaidullina R, Medvedeva M, Vedernikova E, Kozitsina A. Electrochemical behavior of chloramphenicol on carbon electrodes in a microelectrochemical cell. ChimTechActa. 2022;9(4) [Crossref]