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Adv Pharm Bull. 2016;6(2): 195-200. doi: 10.15171/apb.2016.027
PMID: 27478781        PMCID: PMC4961977

Research Article

Development of Floating-Mucoadhesive Microsphere for Site Specific Release of Metronidazole

Md. Lutful Amin 1 * , Tajnin Ahmed 1, Md. Abdul Mannan 1

Cited by CrossRef: 15


1- BHISE M, SHUKLA K, JAIN S, BHAJIPALE N, SUDKE S, BURAKLE P. Development and Evaluation of Floating Microspheres of Anticonvulsant Drug by 32 Full Factorial Design. tjps. 2022;19(5):595 [Crossref]
2- Saha M, Gupta A, Shetty S, Mutalik S, Nandakumar K, Raghu Chandrashekar H, Dhas N, Moorkoth S. DoE-Aided Optimization of RP-HPLC Method for Simultaneous Estimation of Amoxicillin and Tinidazole Loaded Mucoadhesive GRDDS Formulation for the Treatment of H. pylori. Chromatographia. 2024;87(9):533 [Crossref]
3- Rajput K, Tawade S, Nangare S, Shirsath N, Bari S, Zawar L. Formulation, optimization, and in-vitro-ex-vivo evaluation of dual-crosslinked zinc pectinate-neem gum-interpenetrating polymer network mediated lansoprazole loaded floating microbeads. International Journal of Biological Macromolecules. 2022;222:915 [Crossref]
4- Komati S, Swain S, Rao M, Jena B, Dasi V. Mucoadhesive Multiparticulate Drug Delivery Systems: An ExtensiveReview of Patents. Adv Pharm Bull. 2019;9(4):521 [Crossref]
5- Mahmoud D, Schulz‐Siegmund M. Utilizing 4D Printing to Design Smart Gastroretentive, Esophageal, and Intravesical Drug Delivery Systems. Adv Healthcare Materials. 2023;12(10) [Crossref]
6- Patel A, Mishra M, Gupta J, Ghoshal S, Gupta R, Kushwaha K. Guar Gum-Based Floating Microspheres of Repaglinide Using 32 Factorial Design: Fabrication, Optimization, Characterization, and In Vivo Buoyancy Behavior in Albino Rats. ASSAY and Drug Development Technologies. 2021;19(2):63 [Crossref]
7- Kar A, Shil A, Kar B, Dey S. Formulation development and statistical optimization of zingiberol incorporated sodium alginate-methyl cellulose blend microspheres. International Journal of Biological Macromolecules. 2020;162:1578 [Crossref]
8- Srivastava A, Verma A, Saraf S, Jain A, Tiwari A, Panda P, Jain S. Mucoadhesive gastroretentive microparticulate system for programmed delivery of famotidine and clarithromycin. Journal of Microencapsulation. 2021;38(3):151 [Crossref]
9- Briones Nieva C, Real J, Campos S, Romero A, Villegas M, Gonzo E, Bermúdez J, Palma S, Cid A. Modeling and evaluation of ivermectin release kinetics from 3D-printed tablets. Therapeutic Delivery. 2024;15(11):845 [Crossref]
10- Mwila C, Walker R. Improved Stability of Rifampicin in the Presence of Gastric-Resistant Isoniazid Microspheres in Acidic Media. Pharmaceutics. 2020;12(3):234 [Crossref]
11- Mora-Castaño G, Domínguez-Robles J, Himawan A, Millán-Jiménez M, Caraballo I. Current trends in 3D printed gastroretentive floating drug delivery systems: A comprehensive review. International Journal of Pharmaceutics. 2024;663:124543 [Crossref]
12- Grosso R, Benito E, Carbajo-Gordillo A, García-Martín M, Perez-Puyana V, Sánchez-Cid P, de-Paz M. Biodegradable Guar-Gum-Based Super-Porous Matrices for Gastroretentive Controlled Drug Release in the Treatment of Helicobacter pylori: A Proof of Concept. IJMS. 2023;24(3):2281 [Crossref]
13- Deshmukh R, Harwansh R, Rahman M. Sodium alginate-guar gum and carbopol based methotrexate loaded mucoadhesive microparticles for colon delivery: An in vitro evaluation. Braz J Pharm Sci. 2021;57 [Crossref]
14- Grosso R, Benito E, Carbajo-Gordillo A, Díaz M, García-Martín M, de-Paz M. Advanced interpenetrating polymer networks for innovative gastroretentive formulations targeting Helicobacter pylori gastric colonization. European Journal of Pharmaceutical Sciences. 2024;200:106840 [Crossref]
15- Reddy Dumpa N, Bandari S, A. Repka M. Novel Gastroretentive Floating Pulsatile Drug Delivery System Produced via Hot-Melt Extrusion and Fused Deposition Modeling 3D Printing. Pharmaceutics. 2020;12(1):52 [Crossref]
16- Grosso R, de-Paz M. Scope and Limitations of Current Antibiotic Therapies against Helicobacter pylori: Reviewing Amoxicillin Gastroretentive Formulations. Pharmaceutics. 2022;14(7):1340 [Crossref]
17- Aher S, Jain A, Solanki D, Yadav P, Redij S. Timolol Maleate Microspheres: An Ingenious Carrier for Sustained Release Antihypertensive Formulation. J Drug Delivery Ther. 2024;14(11):39 [Crossref]