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Adv Pharm Bull. 2017;7(2): 269-274. doi: 10.15171/apb.2017.032
PMID: 28761829        PMCID: PMC5527241

Research Article

Effects of Pomegranate (Punica Granatum L.) Seed and Peel Methanolic Extracts on Oxidative Stress and Lipid Profile Changes Induced by Methotrexate in Rats

Farideh Doostan 1, Roxana Vafafar 2, Parvin Zakeri-Milani 3, Aliasghar Pouri 3, Rogayeh Amini Afshar 4, Mehran Mesgari Abbasi 5 *

Cited by CrossRef: 28


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12- Taha R, Abdel-Latif G, Said R, Alhajj M. The Prospective Effect of Green Tea versus Pomegranate Peels Extracts on Submandibular Salivary Glands of Albino Rats after Methotrexate Administration (Histological and Immunohistochemical Study). International Journal of Dentistry. 2024;2024:1 [Crossref]
13- Mostafa H, Barakat L, Abdo W, Khalil R. Omega-3 offers better hypothalamus protection by decreasing POMC expression and elevating ghrelin hormone: a prospective trial to overcome methotrexate-induced anorexia. Endocrine. 2020;69(2):358 [Crossref]
14- Seyed Hashemi M, Namiranian N, Tavahen H, Dehghanpour A, Rad M, Jam-Ashkezari S, Emtiazy M, Hashempur M. Efficacy of Pomegranate Seed Powder on Glucose and Lipid Metabolism in Patients with Type 2 Diabetes: A Prospective Randomized Double-Blind Placebo-Controlled Clinical Trial. Complement Med Res. 2021;28(3):226 [Crossref]
15- Özgöçmen M, Aşcı H, Doğan H, İlhan İ, Pekgöz Ş, Mustafaoğlu A. A study on Wistar Albino rats: investigating protective role of ramelteon on liver damage caused by methotrexate. Drug and Chemical Toxicology. 2022;45(6):2678 [Crossref]
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19- Grabež M, Škrbić R, Stojiljković M, Rudić-Grujić V, Paunović M, Arsić A, Petrović S, Vučić V, Mirjanić-Azarić B, Šavikin K, Menković N, Janković T, Vasiljević N. Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study. Journal of Functional Foods. 2020;64:103692 [Crossref]
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25- KORKMAZ Y, GUNGOR H, DEMIRBAS A, DIK B. Pomegranate peel extract, N-Acetylcysteine and their combination with Ornipural alleviate Cadmium-induced toxicity in rats. J Vet Med Sci. 2023;85(9):990 [Crossref]
26- Grabež M, Škrbić R, Stojiljković M, Vučić V, Rudić Grujić V, Jakovljević V, Djuric D, Suručić R, Šavikin K, Bigović D, Vasiljević N. A prospective, randomized, double-blind, placebo-controlled trial of polyphenols on the outcomes of inflammatory factors and oxidative stress in patients with type 2 diabetes mellitus. Rev Cardiovasc Med. 2022;23(2) [Crossref]
27- Smaoui S, Hlima H, Mtibaa A, Fourati M, Sellem I, Elhadef K, Ennouri K, Mellouli L. Pomegranate peel as phenolic compounds source: Advanced analytical strategies and practical use in meat products. Meat Science. 2019;158:107914 [Crossref]
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