Key Immune Cell Cytokines Affects the Telomere Activity of Cord Blood Cells In vitro

Balal Brazvan ^1,2, Raheleh Farahzadi ¹, Seyede Momeneh Mohammadi ^1,2, Soheila Montazer Saheb ¹, Dariush Shanehbandi ³, Laurent Schmied ⁴, Jafar Soleimani Rad ¹, Masoud Darabi ⁵, Hojjatollah Nozad Charoudeh ¹ *

Cited by CrossRef: 29

1- Farahzadi R, Fathi E, Mesbah-Namin S, Zarghami N. Anti-aging protective effect of L-carnitine as clinical agent in regenerative medicine through increasing telomerase activity and change in the hTERT promoter CpG island methylation status of adipose tissue-derived mesenchymal stem cells. Tissue and Cell. 2018;54:105 [Crossref]

2- Wu K, Xu L, Cheng L, Huang T. PAR2 Promoter Hypomethylation Regulates PAR2 Gene Expression and Promotes Lung Adenocarcinoma Cell Progression. Computational and Mathematical Methods in Medicine. 2021;2021:1 [Crossref]

3- Zheng X, Wezel F, Azoitei A, Meessen S, Wang W, Najjar G, Wang X, Kraus J, Kestler H, John A, Zengerling F, Bolenz C, Günes C. Shorter Leukocyte Telomere Length Is Associated with Worse Survival of Patients with Bladder Cancer and Renal Cell Carcinoma. Cancers. 2021;13(15):3774 [Crossref]

4- Meng Y, Yu Z, Wu Y, Du T, Chen S, Meng F, Su N, Ma Y, Li X, Sun S, Zhang G. Cell-based immunotherapy with cytokine-induced killer (CIK) cells: From preparation and testing to clinical application. Human Vaccines & Immunotherapeutics. 2017;13(6):1379 [Crossref]

5- Nguyen V, Mendelsohn A, Larrick J. Interleukin-7 and Immunosenescence. Journal of Immunology Research. 2017;2017:1 [Crossref]

6- Mohammadian A, Naderali E, Mohammadi S, Movasaghpour A, Valipour B, Nouri M, Nozad Charoudeh H. Cord Blood Cells Responses to IL2, IL7 and IL15 Cytokines for mTOR Expression. Adv Pharm Bull. 2017;7(1):81 [Crossref]

7- Montazersaheb S, Avci Ç, Bagca B, Ay N, Tarhriz V, Nielsen P, Charoudeh H, Hejazi M. Targeting TdT gene expression in Molt-4 cells by PNA-octaarginine conjugates. International Journal of Biological Macromolecules. 2020;164:4583 [Crossref]

8- Bagheri Y, Fathi E, Maghoul A, Moshtagh S, Mokhtari K, Abdollahpour A, Montazersaheb S, Bagheri A. Effects of Achillea tenuifolia Lam. hydro-alcoholic extract on anxiety-like behavior and reproductive parameters in rat model of chronic restraint stress. Hum Exp Toxicol. 2021;40(11):1852 [Crossref]

9- Khajepour F, Mahmoodpoor F, Jafari E, Kakaei F, Bahraminia F, Aghajani S, Vahed S, Bagheri Y. Prazosin Protects the Liver Against Renal Ischemia/Reperfusion Injury in Rats. Drug Res (Stuttg). 2023;73(05):289 [Crossref]

10- Liu Z, Zhao W, Yang R. MiR‐1246 is responsible for lung cancer cells‐derived exosomes‐mediated promoting effects on lung cancer stemness via targeting TRIM17. Environmental Toxicology. 2022;37(11):2651 [Crossref]

11- Sarkar A, Saha S, Paul A, Maji A, Roy P, Maity T. Understanding stem cells and its pivotal role in regenerative medicine. Life Sciences. 2021;273:119270 [Crossref]

12- Wei X, Li Y, Zhang G, Wang N, Mi M, Xin Y, Jiang H, Sun C. IL-37 Was Involved in Progress of Acute Myeloid Leukemia Through Regulating IL-6 Expression. CMAR. 2021;Volume 13:3393 [Crossref]

13- Lu Y, Wang W, Tan S. EHD1 promotes the cancer stem cell (CSC)‐like traits of glioma cells via interacting with CD44 and suppressing CD44 degradation. Environmental Toxicology. 2022;37(9):2259 [Crossref]

14- Li S, Huang C, Xiao J, Wu Y, Zhang Z, Zhou Y, Tian N, Wu Y, Wang X, Zhang X. The Potential Role of Cytokines in Diabetic Intervertebral Disc Degeneration. Aging and disease. 2022;13(5):1323 [Crossref]

15- Watanabe S, Hibiya S, Katsukura N, Kitagawa S, Sato A, Okamoto R, Watanabe M, Tsuchiya K. Influence of chronic inflammation on the malignant phenotypes and the plasticity of colorectal cancer cells. Biochemistry and Biophysics Reports. 2021;26:101031 [Crossref]

16- Rahimi M, Bagheri A, Bagheri Y, Fathi E, Bagheri S, Nia A, Jafari S, Montazersaheb S. Renoprotective effects of prazosin on ischemia-reperfusion injury in rats. Hum Exp Toxicol. 2021;40(8):1263 [Crossref]

17- Fathi E, Farahzadi R, Valipour B. Alginate/gelatin encapsulation promotes NK cells differentiation potential of bone marrow resident C-kit+ hematopoietic stem cells. International Journal of Biological Macromolecules. 2021;177:317 [Crossref]

18- Montazersaheb S, Fathi E, Farahzadi R. Cytokines and signaling pathways involved in differentiation potential of hematopoietic stem cells towards natural killer cells. Tissue and Cell. 2021;70:101501 [Crossref]

19- Wang P, Leung J, Lam A, Lee S, Calabrese D, Hays S, Golden J, Kukreja J, Singer J, Wolters P, Tang Q, Greenland J. Lung transplant recipients with idiopathic pulmonary fibrosis have impaired alloreactive immune responses. The Journal of Heart and Lung Transplantation. 2022;41(5):641 [Crossref]

20- Zhang Y, Lin W, Jiang W, Wang Z. MicroRNA-18 facilitates the stemness of gastric cancer by downregulating HMGB3 though targeting Meis2. Bioengineered. 2022;13(4):9959 [Crossref]

21- Fathi E, Farahzadi R. Zinc Sulphate Mediates the Stimulation of Cell Proliferation of Rat Adipose Tissue-Derived Mesenchymal Stem Cells Under High Intensity of EMF Exposure. Biol Trace Elem Res. 2018;184(2):529 [Crossref]

22- Brazvan B, Ebrahimi-Kalan A, Velaei K, Mehdipour A, Aliyari serej Z, Ebrahimi A, Ghorbani M, Cheraghi O, Nozad Charoudeh H. Telomerase activity and telomere on stem progeny senescence. Biomedicine & Pharmacotherapy. 2018;102:9 [Crossref]

23- Dai Y, Yu T, Yu C, Lu T, Zhou L, Cheng C, Ni H. ISG15 enhances glioma cell stemness by promoting Oct4 protein stability. Environmental Toxicology. 2022;37(9):2133 [Crossref]

24- Zole E, Ranka R. Mitochondrial DNA copy number and telomere length in peripheral blood mononuclear cells in comparison with whole blood in three different age groups. Archives of Gerontology and Geriatrics. 2019;83:131 [Crossref]

25- Zhang X, Li H, Chen F, Chen Y, Chai Y, Liao J, Gan B, Chen D, Li S, Liu Y. Icariin regulates miR-23a-3p-mediated osteogenic differentiation of BMSCs via BMP-2/Smad5/Runx2 and WNT/β-catenin pathways in osteonecrosis of the femoral head. Saudi Pharmaceutical Journal. 2021;29(12):1405 [Crossref]

26- Valipour B, Mohammadi S, Abedelahi A, Charoudeh H. The inhibition of ADAM17 in cord blood stem cell-derived CD16+ NK cells to enhance their cytotoxicity against acute lymphoblastic leukemia cells. Human Immunology. 2024;:110769 [Crossref]

27- Fathi E, Vietor I. Mesenchymal Stem Cells Promote Caspase Expression in Molt-4 Leukemia Cells Via GSK-3α/Β and ERK1/2 Signaling Pathways as a Therapeutic Strategy. CGT. 2021;21(1):81 [Crossref]

28- Valipour B, Davari S, Farahzadi R, Pourrasol S, Mehran N, Dizaji Asl K, Altaha S, Hojjati Z, Nozad Charoudeh H. Inhibition of mitochondria induces apoptosis and reduces telomere length and activity in acute myeloid leukemia stem cells. Cell Biochemistry & Function. 2023;41(8):1477 [Crossref]

29- Ni H, Qin H, Sun C, Liu Y, Ruan G, Guo Q, Xi T, Xing Y, Zheng L. MiR-375 reduces the stemness of gastric cancer cells through triggering ferroptosis. Stem Cell Res Ther. 2021;12(1) [Crossref]

30- Farahzadi R, Fathi E, Mesbah-Namin S, Zarghami N, Saretzki G. Zinc sulfate contributes to promote telomere length extension via increasing telomerase gene expression, telomerase activity and change in the TERT gene promoter CpG island methylation status of human adipose-derived mesenchymal stem cells. PLoS ONE. 2017;12(11):e0188052 [Crossref]