Captopril and Valsartan May Improve Cognitive Function Through Potentiation of the Brain Antioxidant Defense System and Attenuation of Oxidative/Nitrosative Damage in STZ-Induced Dementia in Rat

Yasaman Arjmand Abbassi ¹, Mohammad Taghi Mohammadi ² * , Mahsa Sarami Foroshani ³, Javad Raouf Sarshoori ⁴

Cited by CrossRef: 28

1- Mohapatra D, Kanungo S, Pradhan S, Jena S, Prusty S, Sahu P. Captopril is more effective than Perindopril against aluminium chloride induced amyloidogenesis and AD like pathology. Heliyon. 2022;8(2):e08935 [Crossref]

2- Faghihi N, Mohammadi M. Anticonvulsant and Antioxidant Effects of Pitavastatin Against Pentylenetetrazol-Induced Kindling in Mice. Adv Pharm Bull. 2017;7(2):291 [Crossref]

3- Gouveia F, Camins A, Ettcheto M, Bicker J, Falcão A, Cruz M, Fortuna A. Targeting brain Renin-Angiotensin System for the prevention and treatment of Alzheimer’s disease: Past, present and future. Ageing Research Reviews. 2022;77:101612 [Crossref]

4- Jinawong K, Apaijai N, Chattipakorn N, Chattipakorn S. Cognitive impairment in myocardial infarction and heart failure. Acta Physiologica. 2021;232(1) [Crossref]

5- Cai L, Li W, Zeng R, Cao Z, Guo Q, Huang Q, Liu X. Valsartan alleviates the blood–brain barrier dysfunction in db/db diabetic mice. Bioengineered. 2021;12(1):9070 [Crossref]

6- Sarahian N, Mohammadi M, Shahyad S, Rezaei M. Effect of fenofibrate on plasma level of BDNF and brain oxidative stress markers in pentylenetetrazole-induced kindling seizure in mice. Koomesh. 2021;23(5):636 [Crossref]

7- Wei W, Li C, Zhang B, Huang D, Li Z, Gao J. Total Glucosides of Paeony Ameliorate Myocardial Injury in Chronic Heart Failure Rats by Suppressing PARP-1. J of Cardiovasc Trans Res. 2024;17(2):388 [Crossref]

8- Kaeidi A, Amirteimoury M, Zare M, Nazari A, Hakimizadeh E, Hassanshahi J, Fatemi I. Effects of valsartan on morphine tolerance and dependence in rats. 2021;16(3):286 [Crossref]

9- Youssef M, Abd El-Latif H, El-Yamany M, Georgy G. Aliskiren and captopril improve cognitive deficits in poorly controlled STZ-induced diabetic rats via amelioration of the hippocampal P-ERK, GSK3β, P-GSK3β pathway. Toxicology and Applied Pharmacology. 2020;394:114954 [Crossref]

10- Alzahrani Y, Alim A. Sattar M, Kamel F, Ramadan W, Alzahrani Y. Possible combined effect of perindopril and Azilsartan in an experimental model of dementia in rats. Saudi Pharmaceutical Journal. 2020;28(5):574 [Crossref]

11- Aghapour SK F, Sisakhtnezhad S. Effect of the Internal Septum Extract of the Walnut Kernel on the Mesenchymal Stem Cells Cycle and MSCs-derived Insulin-Producing Β-cells Differentiation and Glucose Uptake. Jentashapir J Cell Mol Biol. 2021;12(2) [Crossref]

12- Afra F, Zargaran A, Shirzad N, Hemmatabadi M, Ebrahimpur M, Karimi M, Khanavi M, Mirshekari M, Namazi S. The hypoglycemic effects of Juglans regia L. internal septum in type 2 diabetic patients: A double-blind, randomized, placebo-controlled clinical trial. J Cardiovasc Thorac Res. 2023;15(3):145 [Crossref]

13- Mohapatra D, Kanungo S, Pradhan S, Jena S, Prusty S, Sahu P. Captopril Is More Effective than Perindopril Against Aluminium Chloride Induced Amyloidogenesis and Cognitive Dysfunction. SSRN Journal. 2021; [Crossref]

14- Ahmed H, Ishrat T. The Brain AT2R—a Potential Target for Therapy in Alzheimer’s Disease and Vascular Cognitive Impairment: a Comprehensive Review of Clinical and Experimental Therapeutics. Mol Neurobiol. 2020;57(8):3458 [Crossref]

15- Nesterowicz M, Lauko K, Dańkowska K, Trocka D, Żendzian-Piotrowska M, Ładny J, Zalewska A, Maciejczyk M. Preliminary evaluation of the antiglycoxidant activity of verapamil using various in vitro and in silico biochemical/biophysical methods. Front Pharmacol. 2023;14 [Crossref]

16- Law C, Yeong K. Repurposing Antihypertensive Drugs for the Management of Alzheimer’s Disease. CMC. 2021;28(9):1716 [Crossref]

17- Rasouli Vani J, Taghi Mohammadi M, Sarami Foroshani M, Rezazade E. Evaluation of the neuroprotective and antioxidant effects of Dorema aucheri extract on cerebral ischaemia-reperfusion injury in rats. Pharmaceutical Biology. 2019;57(1):255 [Crossref]

18- Paseban M, Mohebbati R, Niazmand S, Sathyapalan T, Sahebkar A. Comparison of the Neuroprotective Effects of Aspirin, Atorvastatin, Captopril and Metformin in Diabetes Mellitus. Biomolecules. 2019;9(4):118 [Crossref]

19- Topcu A, Saral S, Ozturk A, Saral O, Kaya A. The effect of the calcium channel blocker nimodipine on hippocampal BDNF/Ach levels in rats with experimental cognitive impairment. Neurological Research. 2023;45(6):544 [Crossref]

20- Chang Y, Chou C, Li Y, Huang L, Kao Y, Hueng D, Tsai C. Antiproliferative and apoptotic effects of telmisartan in human glioma cells. Cancer Cell Int. 2023;23(1) [Crossref]

21- Flores-Cuadra J, Madrid A, Fernández P, Pérez-Lao A, Oviedo D, Britton G, Carreira M, Rao K, Britton G, Rocha Arrieta L, Garcia-Cairasco N, Lazarowski A, Palacios A, Espuny A, Maccioni R. Critical Review of the Alzheimer’s Disease Non-Transgenic Models: Can They Contribute to Disease Treatment?. JAD. 2021;82(s1):S227 [Crossref]

22- Sahin B, Ergul M. Captopril exhibits protective effects through anti-inflammatory and anti-apoptotic pathways against hydrogen peroxide-induced oxidative stress in C6 glioma cells. Metab Brain Dis. 2022;37(4):1221 [Crossref]

23- Ionita R, Postu P, Beppe G, Mihasan M, Petre B, Hancianu M, Cioanca O, Hritcu L. Cognitive-enhancing and antioxidant activities of the aqueous extract from Markhamia tomentosa (Benth.) K. Schum. stem bark in a rat model of scopolamine. Behav Brain Funct. 2017;13(1) [Crossref]

24- Asgharzadeh F, Hosseini M, Bargi R, Soukhtanloo M, Beheshti F, Mohammady Z, Anaeigoudari A. Effect of Captopril on Brain Oxidative Damage in Pentylenetetrazole-Induced Seizures in Mice
. Pharm Sci. 2019;25(3):221 [Crossref]

25- Ababei D, Bild V, Macadan I, Vasincu A, Rusu R, Blaj M, Stanciu G, Lefter R, Bild W. Therapeutic Implications of Renin–Angiotensin System Modulators in Alzheimer’s Dementia. Pharmaceutics. 2023;15(9):2290 [Crossref]

26- Li Y, Kong S, Yang F, Xu W. Protective Effects of 2-Amino-5,6-dihydro-4H-1,3-thiazine and Its Derivative against Radiation-Induced Hematopoietic and Intestinal Injury in Mice. IJMS. 2018;19(5):1530 [Crossref]