The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells

Mahshid Saleh ¹, karim Shamsasanjan ^1,2 * , Aliakbar Movassaghpourakbari ¹, Parvin Akbarzadehlaleh ³, Zahra Molaeipour ¹

Cited by CrossRef: 43

1- Stokes D, Felan N, McQuivey K, McGinley B, Frank R. Biologics Approaches—When, Why, and How?. Operative Techniques in Sports Medicine. 2024;32(2):151082 [Crossref]

2- Zhang J, Liu Y, Yin W, Hu X. Adipose-derived stromal cells in regulation of hematopoiesis. Cell Mol Biol Lett. 2020;25(1) [Crossref]

3- Jung S. Adult Stem Cell Treatment for Rheumatoid Arthritis. J Rheum Dis. 2018;25(3):158 [Crossref]

4- Sandoval C, Calle Y, Godoy K, Farías J. An Updated Overview of the Role of CYP450 during Xenobiotic Metabolization in Regulating the Acute Myeloid Leukemia Microenvironment. IJMS. 2023;24(7):6031 [Crossref]

5- Romanov Y, Balashova E, Volgina N, Kabaeva N, Dugina T, Sukhikh G. Expression of Surface Molecules in Human Mesenchymal Stromal Cells Co-Cultured with Nucleated Umbilical Cord Blood Cells. Bull Exp Biol Med. 2017;162(4):578 [Crossref]

6- Aqmasheh S, Shamsasanjan K, Akbarzadehlaleh P, Pashoutan Sarvar D, Timari H. Effects of Mesenchymal Stem Cell Derivatives on Hematopoiesis and Hematopoietic Stem Cells. Adv Pharm Bull. 2017;7(2):165 [Crossref]

7- Mahmoud A, Ibrahim H, El-Sawi M, Habza M. Effects of silymarin and mesenchymal stem cells on hematological and some biochemical changes induced by gamma radiation in albino rats. International Journal of Radiation Biology. 2020;96(2):220 [Crossref]

8- Sahu S, Reddy P, Lu J, Shao Y, Wang C, Tsuji M, Delicado E, Rodriguez Esteban C, Belmonte J. Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging. Sci Transl Med. 2024;16(764) [Crossref]

9- Ozdogan H, Gur Dedeoglu B, Oztemur Islakoglu Y, Aydos A, Kose S, Atalay A, Yegin Z, Avcu F, Uckan Cetinkaya D, Ilhan O. DICER1 gene and miRNA dysregulation in mesenchymal stem cells of patients with myelodysplastic syndrome and acute myeloblastic leukemia. Leukemia Research. 2017;63:62 [Crossref]

10- Fathi E, Azarbad S, Farahzadi R, Javanmardi S, Vietor I. Effect of Rat Bone Marrow Derived-Mesenchymal Stem Cells on Granulocyte Differentiation of Mononuclear Cells as Preclinical Agent in Cellbased Therapy. CGT. 2022;22(2):152 [Crossref]

11- Mansoorabadi Z, Kheirandish M. The upregulation of Gata transcription factors family and FOG-1 in expanded and differentiated cord blood-derived CD34+ hematopoietic stem cells to megakaryocyte lineage during co-culture with cord blood mesenchymal stem cells. Transfusion and Apheresis Science. 2022;61(6):103481 [Crossref]

12- Huang L, Liu Z, Liu H, Ding K, Mi F, Xiang C, Wang G, Guo Y, Fu R, Sánchez-Guijo F. Iron Overload Impairs Bone Marrow Mesenchymal Stromal Cells from Higher-Risk MDS Patients by Regulating the ROS-Related Wnt/β-Catenin Pathway. Stem Cells International. 2020;2020:1 [Crossref]

13- Fol M, Włodarczyk M, Kowalewicz-Kulbat M, Druszczyńska M, Krawczyk K, Wawrocki S, Rudnicka W, Chmiela M. Mycobacterium bovis Wild-Type BCG or Recombinant BCG Secreting Murine IL-18 (rBCG/IL-18) Strains in Driving Immune Responses in Immunocompetent or Immunosuppressed Mice. Vaccines. 2022;10(4):615 [Crossref]

14- Jia Y, Zhang C, Zheng X, Gao M. Co-cultivation of progenitor cells enhanced osteogenic gene expression and angiogenesis potential in vitro. J Int Med Res. 2021;49(4) [Crossref]

15- Hino C, Pham B, Park D, Yang C, Nguyen M, Kaur S, Reeves M, Xu Y, Nishino K, Pu L, Kwon S, Zhong J, Zhang K, Xie L, Chong E, Chen C, Nguyen V, Castillo D, Cao H. Targeting the Tumor Microenvironment in Acute Myeloid Leukemia: The Future of Immunotherapy and Natural Products. Biomedicines. 2022;10(6):1410 [Crossref]

16- Fathi E, Farahzadi R, Sheikhzadeh N. Immunophenotypic characterization, multi-lineage differentiation and aging of zebrafish heart and liver tissue-derived mesenchymal stem cells as a novel approach in stem cell-based therapy. Tissue and Cell. 2019;57:15 [Crossref]

17- Amelirad A, Shamsasenjan K, Akbarzadehlaleh P, Pashoutan Sarvar D. Signaling Pathways of Receptors Involved in Platelet Activation andShedding of These Receptors in Stored Platelets. Adv Pharm Bull. 2019;9(1):38 [Crossref]

18- Cismaru C, Tomuleasa C, Jurj A, Chira S, Isachekcu E, Cismaru G, Gherman L, Gulei D, Munteanu R, Berindan Neagoe I. Synergistic Effect of Human Chorionic Gonadotropin and Granulocyte Colony Stimulating Factor in the Mobilization of HSPCs Improves Overall Survival After PBSCT in a Preclinical Murine Model. Are We Far Enough for Therapy?. Stem Cell Rev and Rep. 2024;20(1):206 [Crossref]

19- Iván J, Major E, Sipos A, Kovács K, Horváth D, Tamás I, Bay P, Dombrádi V, Lontay B. The Short-Chain Fatty Acid Propionate Inhibits Adipogenic Differentiation of Human Chorion-Derived Mesenchymal Stem Cells Through the Free Fatty Acid Receptor 2. Stem Cells and Development. 2017;26(23):1724 [Crossref]

20- He Y, Xu L, Feng F, Wang Q, Zhu X, Wang C, Zhang J, Fu H, Xu L, Liu K, Huang X, Zhang X. Mesenchymal stem cell deficiency influences megakaryocytopoiesis through the TNFAIP3/NF‐κB/SMAD pathway in patients with immune thrombocytopenia. Br J Haematol. 2018;180(3):395 [Crossref]

21- Ciciarello M, Corradi G, Loscocco F, Visani G, Monaco F, Cavo M, Curti A, Isidori A. The Yin and Yang of the Bone Marrow Microenvironment: Pros and Cons of Mesenchymal Stromal Cells in Acute Myeloid Leukemia. Front Oncol. 2019;9 [Crossref]

22- Borriello A, Caldarelli I, Bencivenga D, Stampone E, Perrotta S, Oliva A, Ragione F. Tyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functions. Oncotarget. 2017;8(3):5540 [Crossref]

23- Majidinia M, Aghazadeh J, Jahanban‐Esfahlani R, Yousefi B. The roles of Wnt/β‐catenin pathway in tissue development and regenerative medicine. Journal Cellular Physiology. 2018;233(8):5598 [Crossref]

24- Budgude P, Kale V, Vaidya A. Mesenchymal stromal cell‐derived extracellular vesicles as cell‐free biologics for the ex vivo expansion of hematopoietic stem cells. Cell Biology International. 2020;44(5):1078 [Crossref]

25- Shamsasenjan K, Timari H, Saleh M. The effect of mesenchymal stem cell-derived microvesicles on differentiation of umbilical cord blood-derived CD34+ cells toward myeloid lineage. Gene Reports. 2022;26:101462 [Crossref]

26- Nasr M, Bassi R, Usuelli V, Valderrama-Vasquez A, Tezza S, D’Addio F, Fiorina P. The use of Hematopoietic Stem Cells in Autoimmune Diseases. Regen Med. 2016;11(4):395 [Crossref]

27- Ahmed E, Ahmed N, Medhat A, Said U, Rashed L, Abdel Ghaffar A. Mesenchymal stem cells targeting PI3K/AKT pathway in leukemic model. Tumour Biol. 2019;41(4):101042831984680 [Crossref]

28- Pendse S, Kale V, Vaidya A. The Intercellular Communication Between Mesenchymal Stromal Cells and Hematopoietic Stem Cells Critically Depends on NF-κB Signalling in the Mesenchymal Stromal Cells. Stem Cell Rev and Rep. 2022;18(7):2458 [Crossref]

29- Lia G, Di Vito C, Cerrano M, Brunello L, Calcaterra F, Tapparo M, Giaccone L, Mavilio D, Bruno B. Extracellular Vesicles After Allogeneic Hematopoietic Cell Transplantation: Emerging Role in Post-Transplant Complications. Front Immunol. 2020;11 [Crossref]

30- Mohanty A, Polisetti N, Vemuganti G. Immunomodulatory properties of bone marrow mesenchymal stem cells. J Biosci. 2020;45(1) [Crossref]

31- Sarvar D, Effatpanah H, Akbarzadehlaleh P, Shamsasenjan K. Mesenchymal stromal cell-derived extracellular vesicles: novel approach in hematopoietic stem cell transplantation. Stem Cell Res Ther. 2022;13(1) [Crossref]

32- Srivastava J, Katiyar S, Chaturvedi C, Nityanand S. Extracellular vesicles from bone marrow mesenchymal stromal cells of severe aplastic anemia patients attenuate hematopoietic functions of CD34+ hematopoietic stem and progenitor cells. Cell Biology International. 2022;46(11):1970 [Crossref]

33- Mohammadalipour A, Dumbali S, Wenzel P. Mitochondrial Transfer and Regulators of Mesenchymal Stromal Cell Function and Therapeutic Efficacy. Front Cell Dev Biol. 2020;8 [Crossref]

34- Farahzadi R, Fathi E, Mesbah-Namin S, Zarghami N, Saretzki G. Zinc sulfate contributes to promote telomere length extension via increasing telomerase gene expression, telomerase activity and change in the TERT gene promoter CpG island methylation status of human adipose-derived mesenchymal stem cells. PLoS ONE. 2017;12(11):e0188052 [Crossref]

35- Ishkitiev N, Miteva M, Micheva M, Stoyanova T, Lozanova V, Lozanov V, Mihaylova Z, Cheshmedzhieva D, Kandinska M, Rangelov M, Todorova N, Ilieva S, Baluschev S, Gargallo R, Calenic B, Constantinescu I, Landfester K, Vasilev A. Aggregation induced nucleic acids recognition by homodimeric asymmetric monomethyne cyanine fluorochromes in mesenchymal stem cells. International Journal of Biological Macromolecules. 2023;250:126094 [Crossref]

36- Janagama D, Hui S. 3-D Cell Culture Systems in Bone Marrow Tissue and Organoid Engineering, and BM Phantoms as In Vitro Models of Hematological Cancer Therapeutics—A Review. Materials. 2020;13(24):5609 [Crossref]

37- Darnell M, O’Neil A, Mao A, Gu L, Rubin L, Mooney D. Material microenvironmental properties couple to induce distinct transcriptional programs in mammalian stem cells. Proc Natl Acad Sci USA. 2018;115(36) [Crossref]

38- Feng L, Huang Q, Huang Z, Li H, Qi X, Wang Y, Liu Z, Liu X, Lu L. Optimized Animal Model of Cyclophosphamide‐induced Bone Marrow Suppression. Basic Clin Pharma Tox. 2016;119(5):428 [Crossref]

39- Chen R, Li L, Feng L, Luo Y, Xu M, Leong K, Yao R. Biomaterial-assisted scalable cell production for cell therapy. Biomaterials. 2020;230:119627 [Crossref]

40- Timari H, Shamsasenjan K, Movassaghpour A, Akbarzadehlaleh P, Pashoutan Sarvar D, Aqmasheh S. The Effect of Mesenchymal Stem Cell-Derived Extracellular Vesicles on Hematopoietic Stem Cells Fate. Adv Pharm Bull. 2017;7(4):531 [Crossref]

41- Mallis P, Michalopoulos E, Chatzistamatiou T, Stavropoulos-Giokas C. Mesenchymal stromal cells as potential immunomodulatory players in severe acute respiratory distress syndrome induced by SARS-CoV-2 infection. WJSC. 2020;12(8):731 [Crossref]

42- Gynn L, Anderson E, Robinson G, Wexler S, Upstill-Goddard G, Cox C, May J. Primary mesenchymal stromal cells in co-culture with leukaemic HL-60 cells are sensitised to cytarabine-induced genotoxicity, while leukaemic cells are protected. 2021;36(6):419 [Crossref]