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Adv Pharm Bull. 2017;7(4): 495-500. doi: 10.15171/apb.2017.061
PMID: 29399539        PMCID: PMC5788204

Editorial

Chirality of Modern Antidepressants: An Overview

Monica Budău 1, Gabriel Hancu 1 * , Aura Rusu 1, Melania Cârcu-Dobrin 1, Daniela Lucia Muntean 2

Cited by CrossRef: 41


1- Karadurmus L, Gumustas M, Bakirhan N, Ozkan S. Chiral Sensing as a Future Challenge in Electroanalytical Chemistry: Cyclodextrin-Based Chiral Sensors. Critical Reviews in Analytical Chemistry. 2023;53(3):498 [Crossref]
2- Vashistha V, Sethi S, Tyagi I, Das D. Chirality of antidepressive drugs: an overview of stereoselectivity. 2022;16(2):55 [Crossref]
3- Hancu G, Uilăcan A, Blebea N. Chirality in Modern Antidepressants: A Comprehensive Review of Stereochemical Impacts on Pharmacology and Therapeutics. DDC. 2024;3(4):654 [Crossref]
4- Hancu G, Budău M, Muntean D, Gagyi L, Rusu A. Capillary electrophoresis in the enantioseparation of modern antidepressants: An overview. Biomedical Chromatography. 2018;32(11) [Crossref]
5- Abdul Keyon A, Miskam M, Ishak N, Mahat N, Mohamed Huri M, Abdul Wahab R, Chandren S, Abdul Razak F, Ng N, Ali T. Capillary electrophoresis for the analysis of antidepressant drugs: A review. J of Separation Science. 2019;42(4):906 [Crossref]
6- Davis M, Zhu W, Lee J, Lezec H, Agrawal A. Microscopic origin of the chiroptical response of optical media. Sci Adv. 2019;5(10) [Crossref]
7- Gebauer L, Jensen O, Rafehi M, Brockmöller J. Stereoselective Inhibition of High- and Low-Affinity Organic Cation Transporters. Mol Pharmaceutics. 2023;20(12):6289 [Crossref]
8- Milan A, Hancu G, Lupu D, Budău M, Garaj V, Kelemen H. Venlafaxine Chiral Separation by Capillary Electrophoresis Using Cyclodextrin Derivatives as Chiral Selector and Experimental Design Method Optimization. Symmetry. 2020;12(5):849 [Crossref]
9- Miao P, Gan J, Zhang J, Ma M, Li X, Du Y, Feng Z, Zhang L. Carboxymethyl‐β‐cyclodextrin and histidine‐zeolitic imidazolate framework‐8 used for enantioseparation of three basic drugs in open‐tubular capillary electrochromatography. Chirality. 2022;34(9):1209 [Crossref]
10- Natarajan R, Lungu C, Basak S. Chirality descriptors for structure–activity relationship modeling of bioactive molecules. J Math Chem. 2024;62(10):2388 [Crossref]
11- Huddart R, Hicks J, Ramsey L, Strawn J, Smith D, Bobonis Babilonia M, Altman R, Klein T. PharmGKB summary: sertraline pathway, pharmacokinetics. 2020;30(2):26 [Crossref]
12- Ma M, Zhang J, Zhang X, Kan Z, Du Y. Zeolitic imidazolate framework‐67–modified open‐tubular column with cyclodextrin for enantioseparation in capillary electrochromatography. Electrophoresis. 2022;43(13-14):1415 [Crossref]
13- Hatit M, Dobrowolski C, Lokugamage M, Loughrey D, Ni H, Zurla C, Da Silva Sanchez A, Radmand A, Huayamares S, Zenhausern R, Paunovska K, Peck H, Kim J, Sato M, Feldman J, Rivera M, Cristian A, Kim Y, Santangelo P, Dahlman J. Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery. Nat Chem. 2023;15(4):508 [Crossref]
14- Rebelo P, Pacheco J, Voroshylova I, Seguro I, Cordeiro M, Delerue-Matos C. Computational Modelling and Sustainable Synthesis of a Highly Selective Electrochemical MIP-Based Sensor for Citalopram Detection. Molecules. 2022;27(10):3315 [Crossref]
15- Wu R, Ruan Y, Lin H, Yuen C, Feng H, Lam P. Occurrence and Fate of Psychiatric Pharmaceuticals in Wastewater Treatment Plants in Hong Kong: Enantiomeric Profiling and Preliminary Risk Assessment. ACS EST Water. 2021;1(3):542 [Crossref]
16- Bhadbhade M, Gao J, Rich A, Marjo C. Structure of racemic duloxetine hydrochloride. Acta Crystallogr E Cryst Commun. 2023;79(5):488 [Crossref]
17- Kucwaj-Brysz K, Baś S, Żesławska E, Podlewska S, Jastrzębska-Więsek M, Partyka A, Nitek W, Satała G, Wesołowska A, Handzlik J. The Importance of Stereochemistry in 5-HT7R Modulation─A Case Study of Hydantoin Derivatives. ACS Chem Neurosci. 2024;15(21):3884 [Crossref]
18- Ma X, Du Y, Sun X, Liu J, Huang Z. Synthesis and application of amino alcohol-derived chiral ionic liquids, as additives for enantioseparation in capillary electrophoresis. Journal of Chromatography A. 2019;1601:340 [Crossref]
19- Kaviani R, Jouyban A, Javan M, Seyfinejad B, Shayanfar A. Enantioseparation strategies for sertraline by instrumental and crystallization‐based techniques: An important issue in quality control. Biomedical Chromatography. 2024;38(12) [Crossref]
20- Cantatore C, Bertocchi P, De Orsi D, Panusa A, Cirilli R. Enantioselective HPLC analysis of escitalopram oxalate and its impurities using a cellulose‐based chiral stationary phase under normal‐ and green reversed‐phase conditions. J of Separation Science. 2022;45(5):1059 [Crossref]
21- Thoonen S, Tay H, Hua C. A chiral binaphthyl-based coordination polymer as an enantioselective fluorescence sensor. Chem Commun. 2022;58(28):4512 [Crossref]
22- Cameron M, Taylor C, Lapidus J, Ramsey K, Koop D, Spain R. Gastrointestinal Tolerability and Absorption ofR‐VersusR,S‐Lipoic Acid in Progressive Multiple Sclerosis: A Randomized Crossover Trial. The Journal of Clinical Pharma. 2020;60(8):1099 [Crossref]
23- Malyshko E, Semenova E, Bagrova O, Murtazina A, Tverdislov V. Chiral Dualism as a Unifying Principle in Molecular Biophysics. Biophysica. 2021;1(1):22 [Crossref]
24- Xiao Y, Zhang R, Gao H, Zhao H, Cheng X. Benzothiadiazole-based bolaamphiphiles: synthesis, self-assembly and white-light emissive properties. J Mater Chem C. 2019;7(5):1237 [Crossref]
25- Sethi S, Bhushan R. EnantioselectiveLCanalysis and determination of selective serotonin reuptake inhibitors. Biomedical Chromatography. 2020;34(1) [Crossref]
26- Wyska E. Pharmacokinetic considerations for current state-of-the-art antidepressants. Expert Opinion on Drug Metabolism & Toxicology. 2019;15(10):831 [Crossref]
27- Rosetti A, Ferretti R, Villani C, Pierini M, Cirilli R. Simultaneous enantio- and diastereo-selective high-performance liquid chromatography separation of paroxetine on an immobilized amylose-based chiral stationary phase under green reversed-phase conditions. Journal of Chromatography A. 2021;1653:462406 [Crossref]
28- Derazshamshir A, Göktürk I, Yılmaz F, Denizli A. S‐citalopram imprinted monolithic columns for capillary electrochromatography enantioseparations. Electrophoresis. 2021;42(24):2672 [Crossref]
29- Zeppelin T, Ladefoged L, Sinning S, Schiøtt B. Substrate and inhibitor binding to the serotonin transporter: Insights from computational, crystallographic, and functional studies. Neuropharmacology. 2019;161:107548 [Crossref]
30- Ma X, Du Y, Zhu X, Feng Z, Chen C, Yang J. Evaluation of an ionic liquid chiral selector based on clindamycin phosphate in capillary electrophoresis. Anal Bioanal Chem. 2019;411(22):5855 [Crossref]
31- Zhu J, Zhu L, Wu Y, Cheng L, Wang H, Sun X, Shen J, Zhou Y, Ke Y. A novel C2 symmetric chiral stationary phase with N‐[(4‐Methylphenyl)sulfonyl]‐l‐leucine as chiral side chains. J of Separation Science. 2020;43(12):2338 [Crossref]
32- Barzkar N, Sohail M, Tamadoni Jahromi S, Gozari M, Poormozaffar S, Nahavandi R, Hafezieh M. Marine Bacterial Esterases: Emerging Biocatalysts for Industrial Applications. Appl Biochem Biotechnol. 2021;193(4):1187 [Crossref]
33- Bernardo A, Lee P, Marcotte M, Mian M, Rezvanian S, Sharmin D, Kovačević A, Savić M, Cook J, Sibille E, Prevot T. Symptomatic and neurotrophic effects of GABAA receptor positive allosteric modulation in a mouse model of chronic stress. Neuropsychopharmacol. 2022;47(9):1608 [Crossref]
34- Davis M, Zhu W, Strait J, Lee J, Lezec H, Blair S, Agrawal A. Chiroptical Response of Aluminum Nanocrescents at Ultraviolet Wavelengths. Nano Lett. 2020;20(5):3656 [Crossref]
35- Rosetti A, Ferretti R, Zanitti L, Casulli A, Villani C, Cirilli R. Single-run reversed-phase HPLC method for determining sertraline content, enantiomeric purity, and related substances in drug substance and finished product. Journal of Pharmaceutical Analysis. 2020;10(6):610 [Crossref]
36- Belova E, Semenova E, Tverdislov V. On the Chirality of Drugs and the Structures of Biomacromolecules. BIOPHYSICS. 2022;67(3):374 [Crossref]
37- Bishnoi S, Sharma A, Singhal R, Goyal R. Edge plane pyrolytic graphite as a sensing surface for the determination of fluvoxamine in urine samples of obsessive-compulsive disorder patients. Biosensors and Bioelectronics. 2020;168:112489 [Crossref]
38- Ribeiro O, Félix L, Ribeiro C, Castro B, Tiritan M, Monteiro S, Carrola J. Enantioselective Ecotoxicity of Venlafaxine in Aquatic Organisms: Daphnia and Zebrafish. Enviro Toxic and Chemistry. 2022;41(8):1851 [Crossref]