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Adv Pharm Bull. 2019;9(4): 593-600. doi: 10.15171/apb.2019.068
PMID: 31857963        PMCID: PMC6912175

Research Article

Preparation and Evaluation of Eudragit® L100 Nanoparticles Loaded Impregnated with KT Tromethamine Loaded PVA -HEC Insertions for Ophthalmic Drug Delivery

Ghobad Mohammadi 1 ORCID, Shahla Mirzaeei 1 * ORCID, Shiva Taghe 1, Pardis Mohammadi 1 ORCID

Cited by CrossRef: 15


1- Pelusi L, Mandatori D, Mastropasqua L, Agnifili L, Allegretti M, Nubile M, Pandolfi A. Innovation in the Development of Synthetic and Natural Ocular Drug Delivery Systems for Eye Diseases Treatment: Focusing on Drug-Loaded Ocular Inserts, Contacts, and Intraocular Lenses. Pharmaceutics. 2023;15(2):625 [Crossref]
2- Gabai A, Zeppieri M, Finocchio L, Salati C. Innovative Strategies for Drug Delivery to the Ocular Posterior Segment. Pharmaceutics. 2023;15(7):1862 [Crossref]
3- Öztürk A, Çevikelli T, Tilki E, Güven U, Kıyan H. Ketorolac Tromethamine Loaded Nano-Spray Dried Nanoparticles: Preparation, Characterization, Cell Viability, COL1A1 Gene Simulation and Determination of Anti-inflammatory Activity by In vivo HET-CAM Assay. CDD. 2023;20(6):830 [Crossref]
4- Cortés H, Hernández-Parra H, Bernal-Chávez S, Prado-Audelo M, Caballero-Florán I, Borbolla-Jiménez F, González-Torres M, Magaña J, Leyva-Gómez G. Non-Ionic Surfactants for Stabilization of Polymeric Nanoparticles for Biomedical Uses. Materials. 2021;14(12):3197 [Crossref]
5- Peter S, Mathews M, Saju F, Paul S. Development, Optimization and In Vitro Characterization of Eudragit-Ganciclovir Nanosuspension or Treating Herpes Simplex Keratitis. J Pharm Innov. 2023;18(3):1328 [Crossref]
6- Mirzaeei S, Taghe S, Alany R, Nokhodchi A. Eudragit® L100/Polyvinyl Alcohol Nanoparticles Impregnated Mucoadhesive Films as Ocular Inserts for Controlled Delivery of Erythromycin: Development, Characterization and In Vivo Evaluation. Biomedicines. 2022;10(8):1917 [Crossref]
7- Cardoso A, Oliveira E, Machado B, Marcelino H. Eudragit®-based nanoparticles for controlled release through topical use. J Nanopart Res. 2023;25(2) [Crossref]
8- Farahmandnejad M, Alipour S, Nokhodchi A. Physical and mechanical properties of ocular thin films: a systematic review and meta-analysis. Drug Discovery Today. 2024;29(5):103964 [Crossref]
9- Dourado L, Silva C, Gonçalves R, Inoue T, de Lima M, Cunha-Júnior A. Improvement of PnPP-19 peptide bioavailability for glaucoma therapy: Design and application of nanowafers based on PVA. Journal of Drug Delivery Science and Technology. 2022;74:103501 [Crossref]
10- Taghe S, Mirzaeei S, Bagheri M. Preparation of polycaprolactone and polymethacrylate nanofibers for controlled ocular delivery of ketorolac tromethamine: Pharmacokinetic study in Rabbit's Eye. European Journal of Pharmaceutical Sciences. 2024;192:106631 [Crossref]
11- Zhang M, Qiu B, Sun M, Wang Y, Wei M, Gong Y, Yan M. Preparation of Black pepper (Piper nigrum L.) essential oil nanoparticles and its antitumor activity on triple negative breast cancer in vitro . Journal of Food Biochemistry. 2022;46(12) [Crossref]
12- Rosiak N, Tykarska E, Cielecka-Piontek J. The Study of Amorphous Kaempferol Dispersions Involving FT-IR Spectroscopy. IJMS. 2023;24(24):17155 [Crossref]
13- Taghe S, Mirzaeei S, Alany R, Nokhodchi A. Polymeric Inserts Containing Eudragit® L100 Nanoparticle for Improved Ocular Delivery of Azithromycin. Biomedicines. 2020;8(11):466 [Crossref]
14- Mirzaeei S, Barfar D. Design and Development of Antibacterial/Anti-inflammatory Dual Drug-Loaded Nanofibrous Inserts for Ophthalmic Sustained Delivery of Gentamicin and Methylprednisolone: In Vitro Bioassay, Solvent, and Method Effects’ Evaluation. Adv Pharm Bull. 2022;12(3):531 [Crossref]
15- Aghajannataj Ahangarkola F, Najafpour-Darzi G, Ramezani Kalmer R. Towards a novel pullulan and pullulan-enteric hard capsules: Study of drug release and crucial capsule features. Journal of Drug Delivery Science and Technology. 2024;92:105297 [Crossref]
16- Mehrandish S, Mohammadi G, Mirzaeei S. Preparation and functional evaluation of electrospun polymeric nanofibers as a new system for sustained topical ocular delivery of itraconazole. Pharmaceutical Development and Technology. 2022;27(1):25 [Crossref]
17- Kaya S, Kondolot Solak E. Development of ketorolac tromethamine loaded biocompatible polymeric microspheres and matrix films: designing for topical application. International Journal of Polymeric Materials and Polymeric Biomaterials. 2023;72(17):1329 [Crossref]
18- Yu S, Piao H, Rejinold N, Lee H, Choi G, Choy J. pH-Responsive Inorganic/Organic Nanohybrids System for Controlled Nicotinic Acid Drug Release. Molecules. 2022;27(19):6439 [Crossref]
19- Teba H, Khalil I, Gebreel R, Fahmy L, Sorogy H. Development of antifungal fibrous ocular insert using freeze-drying technique. Drug Deliv and Transl Res. 2024; [Crossref]
20- Gupta B, Mishra V, Gharat S, Momin M, Omri A. Cellulosic Polymers for Enhancing Drug Bioavailability in Ocular Drug Delivery Systems. Pharmaceuticals. 2021;14(11):1201 [Crossref]