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Adv Pharm Bull. 2018;8(4): 575-590. doi: 10.15171/apb.2018.066
PMID: 30607330        PMCID: PMC6311642

Review Article

A Review of Herbal Therapy in Multiple Sclerosis

Sina Mojaverrostami 1 * ORCID, Maryam Nazm Bojnordi 2,3, Maryam Ghasemi-Kasman 4 ORCID, Mohammad Ali Ebrahimzadeh 5 ORCID, Hatef Ghasemi Hamidabadi 2,6 ORCID

Cited by CrossRef: 39


1- Arcusa R, Villaño D, Marhuenda J, Cano M, Cerdà B, Zafrilla P. Potential Role of Ginger (Zingiber officinale Roscoe) in the Prevention of Neurodegenerative Diseases. Front Nutr. 2022;9 [Crossref]
2- Oh J, Kwon T, Choi J, Kim Y, Moon S, Nah S, Cho I. Ginsenoside-Re inhibits experimental autoimmune encephalomyelitis as a mouse model of multiple sclerosis by downregulating TLR4/MyD88/NF-κB signaling pathways. Phytomedicine. 2024;122:155065 [Crossref]
3- Brockmueller A, Mahmoudi N, Movaeni A, Mueller A, Kajbafzadeh A, Shakibaei M, Zolbin M. Stem Cells and Natural Agents in the Management of Neurodegenerative Diseases: A New Approach. Neurochem Res. 2023;48(1):39 [Crossref]
4- Javanbakht P, Taghizadeh F, Takabi F, Tajik M, Iranshahi S, Pasbakhsh P, Kashani I, Mojaverrostami S. Effects of Calorie Restriction on Multiple Sclerosis: A Review of the Preclinical and Clinical Studies. Neurochem Res. 2023;48(6):1597 [Crossref]
5- Novikov Y, Akopyan A, Derevyanko K. Use of complementary medicine in autoimmune diseases of the nervous system.. Bulletin of Neurology, Psychiatry and Neurosurgery. 2022;(10):803 [Crossref]
6- Gentile M, Muto G, Lus G, Lövblad K, Svenningsen Å, Colucci-D’Amato L. Angiogenesis and Multiple Sclerosis Pathogenesis: A Glance at New Pharmaceutical Approaches. JCM. 2022;11(16):4643 [Crossref]
7- Interdonato L, Marino Y, Impellizzeri D, D’Amico R, Siracusa R, Fusco R, Cammilleri G, Pantano L, Modafferi S, Abdelhameed A, Fritsch T, Rashan L, Cuzzocrea S, Calabrese V, Cordaro M, Di Paola R. Autophagy machinery plays an essential role in traumatic brain injury-induced apoptosis and its related behavioral abnormalities in mice: focus on Boswellia Sacra gum resin. Front Physiol. 2024;14 [Crossref]
8- Concerto C, Rodolico A, Ciancio A, Messina C, Natale A, Mineo L, Battaglia F, Aguglia E. Vitamin D and Depressive Symptoms in Adults with Multiple Sclerosis: A Scoping Review. IJERPH. 2021;19(1):199 [Crossref]
9- Bosch-Morell F, Villagrasa V, Ortega T, Acero N, Muñoz-Mingarro D, González-Rosende M, Castillo E, Sanahuja M, Soriano P, Martínez-Solís I. Medicinal plants and natural products as neuroprotective agents in age-related macular degeneration. Neural Regen Res. 2020;15(12):2207 [Crossref]
10- Mojaverrostami S, Pasbakhsh P, Madadi S, Nekoonam S, Zarini D, Noori L, Shiri E, Salama M, Zibara K, Kashani I. Calorie restriction promotes remyelination in a Cuprizone-Induced demyelination mouse model of multiple sclerosis. Metab Brain Dis. 2020;35(7):1211 [Crossref]
11- Alharbi S, Asad M, Abdelsalam K, Ibrahim M, Chandy S. Beneficial Effect of Methanolic Extract of Frankincense (Boswellia Sacra) on Testis Mediated through Suppression of Oxidative Stress and Apoptosis. Molecules. 2022;27(15):4699 [Crossref]
12- Costantini E, Masciarelli E, Casorri L, Di Luigi M, Reale M. Medicinal herbs and multiple sclerosis: Overview on the hard balance between new therapeutic strategy and occupational health risk. Front Cell Neurosci. 2022;16 [Crossref]
13- Gupta A, Roy A, Pandit S, Pandey N, Rustagi S. Evaluation of Bioactive Compounds Obtained from Ginkgo Biloba Against Crystal Structure of Myelin Oligodendrocyte Glycoprotein (MOG). OBM Neurobiol. 2023;07(04):1 [Crossref]
14- Yu W, Wang Q, Chen S, Cao L, Tang J, Ma C, Xiao W, Xiao B. The therapeutic potential of ginkgolide K in experimental autoimmune encephalomyelitis via peripheral immunomodulation. International Immunopharmacology. 2019;70:284 [Crossref]
15- Song L, Han Q, Ding Z, Liu K, Zhang X, Guo M, Ma D, Wang Q, Xiao B, Ma C. Icariin ameliorates the cuprizone-induced demyelination associated with antioxidation and anti-inflammation. Inflammopharmacol. 2024;32(1):809 [Crossref]
16- Batiha G, Lukman H, Shaheen H, Wasef L, Hafiz A, Conte-Junior C, Al-Farga A, Chamba M, Lawal B, Abu Bakar M. A Systematic Review of Phytochemistry, Nutritional Composition, and Pharmacologic Application of Species of the Genus Viola in Noncommunicable Diseases (NCDs). Evidence-Based Complementary and Alternative Medicine. 2023;2023:1 [Crossref]
17- DEMİRCİ T. The protective role of Hypericum perforatum in treatment of oxidative stress-induced multiple sclerosis is affected by extraction procedure: A literature review. 2019;11(0):17 [Crossref]
18- Moradi V, Esfandiary E, Ghanadian M, Ghasemi N, Rashidi B. The effect of Zingiber Officinale Extract on Preventing Demyelination of Corpus Callosum in a Rat Model of Multiple Sclerosis. IBJ. 2022;26(4):330 [Crossref]
19- Kim H, Kim T, Cho W, Chang H, Chung W. Traditional Chinese medicine for gait disturbance in adrenoleukodystrophy: A case report and review of literature. WJCC. 2021;9(31):9691 [Crossref]
20- Babich O, Larina V, Ivanova S, Tarasov A, Povydysh M, Orlova A, Strugar J, Sukhikh S. Phytotherapeutic Approaches to the Prevention of Age-Related Changes and the Extension of Active Longevity. Molecules. 2022;27(7):2276 [Crossref]
21- Korani S, Korani M, Sathyapalan T, Sahebkar A. Therapeutic effects of Crocin in autoimmune diseases: A review. BioFactors. 2019;45(6):835 [Crossref]
22- Herrera J, Niehaus W, Whiteson J, Azola A, Baratta J, Fleming T, Kim S, Naqvi H, Sampsel S, Silver J, Verduzco‐Gutierrez M, Maley J, Herman E, Abramoff B. Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fatigue in postacute sequelae of SARS‐CoV‐2 infection (PASC) patients. PM&R. 2021;13(9):1027 [Crossref]
23- Ravi A, Muthukrishnan S. Combination of Probiotics and Natural Compounds to Treat Multiple Sclerosis via Warburg Effect. Adv Pharm Bull. 2022;12(3):515 [Crossref]
24- Liu Y, Li J, Wang X, Liu Y, Zhang C, Chabalala H, Tang M. Ginsenoside Rb1 attenuates lipopolysaccharide-induced chronic neuroinflammation in mice by tuning glial cell polarization. Journal of Traditional Chinese Medical Sciences. 2022;9(4):383 [Crossref]
25- Petersen M, Bergien S, Staerk D. A systematic review of possible interactions for herbal medicines and dietary supplements used concomitantly with disease‐modifying or symptom‐alleviating multiple sclerosis drugs. Phytotherapy Research. 2021;35(7):3610 [Crossref]
26- Čulić A, Bregar B, Macur M. Raba konoplje v medicinske namene. Obzor Zdrav Neg. 2021;55(4) [Crossref]
27- Kiriacos C, Khedr M, Tadros M, Youness R. Prospective Medicinal Plants and Their Phytochemicals Shielding Autoimmune and Cancer Patients Against the SARS-CoV-2 Pandemic: A Special Focus on Matcha. Front Oncol. 2022;12 [Crossref]
28- Bravo-Vázquez L, Mora-Hernández E, Rodríguez A, Sahare P, Bandyopadhyay A, Duttaroy A, Paul S. Current Advances of Plant-Based Vaccines for Neurodegenerative Diseases. Pharmaceutics. 2023;15(2):711 [Crossref]
29- Lee M, Choi J, Kwon T, Jo H, Ha Y, Nah S, Cho I. Korean Red Ginseng extract ameliorates demyelination by inhibiting infiltration and activation of immune cells in cuprizone-administrated mice. Journal of Ginseng Research. 2023;47(5):672 [Crossref]
30- Zhao R, Zhang G, Zhang W, Yu W, Du L, Toledo M, Olivera Leal I, O’Farrill Z, Izquierdo G. Ocular manifestations of multiple sclerosis in patients from three countries: A Web-based survey. European Journal of Ophthalmology. 2022;32(5):2975 [Crossref]
31- Alharbi S, Asad M, Abdelsalam K, Chandy S, Ibrahim M. Frankincense extract protects against testicular damage through augmentation of antioxidant defense mechanisms and modulation of apoptotic genes expression. Sci Rep. 2022;12(1) [Crossref]
32- Javanbakht P, Yazdi F, Taghizadeh F, Khadivi F, Hamidabadi H, Kashani I, Zarini D, Mojaverrostami S. Quercetin as a possible complementary therapy in multiple sclerosis: Anti-oxidative, anti-inflammatory and remyelination potential properties. Heliyon. 2023;9(11):e21741 [Crossref]
33- BULUT H, TELOĞLU E, ŞENTÜRK H, ÜSTÜNOVA S, GÜLEKEN Z, SELEK Ş. ÇUHA ÇİÇEĞİ VE SARI KANTARON YAĞLARININ MULTİPLE SKLEROZ MODELİ OLUŞTURULMUŞ FARELERDEKİ JAK/STAT SİNYAL YOLAKLARI ÜZERİNE ETKİSİ. 2022;24(2):225 [Crossref]
34- Namazi F, Bordbar E, Bakhshaei F, Nazifi S. The effect of Urtica dioica extract on oxidative stress, heat shock proteins, and brain histopathology in multiple sclerosis model. Physiological Reports. 2022;10(15) [Crossref]
35- Seo Y, Jin C, Cho S, Park S, Jung W, Moon S, Park J, Ko C, Cho K, Kwon S. Current Utilization and Research Status of Traditional East Asian Herbal Medicine Treatment for Multiple Sclerosis: A Scoping Review. Front Neurol. 2021;12 [Crossref]
36- Cliver R, Castro N, Russomano T, Lardieri G, Quarrie L, van der Merwe H, Vazquez M. Antioxidants Derived from Natural Products Reduce Radiative Damage in Cultured Retinal Glia to Prevent Oxidative Stress. Neuroglia. 2022;3(3):84 [Crossref]
37- Khodanovich M, Pishchelko A, Glazacheva V, Pan E, Krutenkova E, Trusov V, Yarnykh V. Plant polyprenols reduce demyelination and recover impaired oligodendrogenesis and neurogenesis in the cuprizone murine model of multiple sclerosis. Phytotherapy Research. 2019;33(5):1363 [Crossref]
38- Choi J, Oh J, Lee M, Ko S, Nah S, Cho I. Gintonin mitigates experimental autoimmune encephalomyelitis by stabilization of Nrf2 signaling via stimulation of lysophosphatidic acid receptors. Brain, Behavior, and Immunity. 2021;93:384 [Crossref]
39- Salehi N, Nourbakhsh M, Noori S, Rezaeizadeh H, Zarghi A. Tehranolid and Artemisinin Effects on Ameliorating Experimental Autoimmune Encephalomyelitis by Modulating Inflammation and Remyelination. Mol Neurobiol. 2023;60(10):5975 [Crossref]
40- RAIMI M, Nadeem A, Raheem K, Hussain G, Zafeer N, Hamadou M, Irfan M, Nandwa J, Ahmad F, Ullah A, Shabbir A. In silico analysis of RPS4X (X-linked ribosomal protein) with active components from black seed (Nigella sativa) for potential treatment of multiple sclerosis. Journal of Molecular Structure. 2024;1297:136909 [Crossref]
41- Jadideslam G, Kahroba H, Ansarin K, Sakhinia E, Abhar A, Alipour S, Farhadi J, Seydi Shirvani S, Nouri-Vaskeh M, Mousavi S, khabbazi A. Interleukin-17 mRNA expression and serum levels in Behçet’s disease. Cytokine. 2020;127:154994 [Crossref]