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Adv Pharm Bull. 2019;9(1): 147-158. doi: 10.15171/apb.2019.018
PMID: 31011569        PMCID: PMC6468233

Research Article

Enantioselective Box Behenken Optimized HPLC-DAD Method for the Simultaneous Estimation of Alogliptin Enantiomorphs in Pharmaceutical For mulations and their Pharmacokinetic Study in Rat Plasma

Ravi Kant 1 * ORCID, Ramesh Babu Bodla 1, Rubina Bhutani 1 ORCID, Garima Kapoor 1 ORCID

Cited by CrossRef: 7


1- Derar A, Ahmed N, Hussien E. A new strategy for the determination of the antidiabetics alogliptin, saxagliptin and vildagliptin using all-solid state potentiometric sensors. BMC Chemistry. 2023;17(1) [Crossref]
2- Qin Q, Hu S, Dong J, Yin H, Yu J, Liu J, Huang S, Zhang X, Wang L, Fang L, Li M. Application of Plackett-Burman Experimental Design for Investigating the Effect of Eight Phytohormones on Malt Quality Parameters. Journal of the American Society of Brewing Chemists. 2023;81(3):416 [Crossref]
3- Tammam A, Gahlan A, Taher M, Haredy A. Hantzsch condensation reaction as a spectrofluorometric method for determination of alogliptin, an antidiabetic drug, in pure form, tablet form, and human and rat plasma. Luminescence. 2022;37(4):543 [Crossref]
4- Salem W, Elkady E, Fouad M, Abdul-Azim Mohammad M. Analysis of Metformin and Five Gliptins in Counterfeit Herbal Products: Designs of Experiment Screening and Optimization. 2021;104(6):1667 [Crossref]
5- Grybinik S, Bosakova Z. An overview of chiral separations of pharmaceutically active substances by HPLC (2018–2020). Monatsh Chem. 2021;152(9):1033 [Crossref]
6- Hadawale S, Sharma S. Analytical and Bioanalytical Methods for the Determination of Dipeptidyl Peptidase-4 Inhibitors in Various Matrices: A Comprehensive Review. CDR. 2025;21(5) [Crossref]
7- Spandana T, Beeraka N, Hemanth Vikram P, Goli V, Devi Sri C, Gurupadayya B. Technical Advances in the Chiral Separation of Anti-diabetic Drugs Using Analytical and Bio-analytical Methods: A Comprehensive Review. CAC. 2022;18(10):1057 [Crossref]
8- Derayea S, Gahlan A, Omar M, Saleh G, Haredy A. Spectrofluorometric determination of alogliptin an antidiabetic drug in pure and tablet form using fluorescamine, a fluorogenic agent: application to content uniformity test. Luminescence. 2020;35(7):1028 [Crossref]