Determination of the Predictive Value of Serum Bilirubin in Patients with Ischemic Stroke: A Prospective Descriptive Analytical Study

Elnaz Sagheb Asl ¹ , Aliakbar Taheraghdam ² , Farzad Rahmani ¹ , Reza Javadrashid ³ , Samad Eslam Jamal Golzari ⁴ , Neda Ghaemian ⁵ , Yalda Sadeghpour ⁶ , Robab Mehdizadeh Esfanjani ² , Hassan Soleimanpour ² *

Cited by CrossRef: 16

1- Fu K, Garvan C, Heaton S, Nagaraja N, Doré S. Association of Serum Bilirubin with the Severity and Outcomes of Intracerebral Hemorrhages. Antioxidants. 2021;10(9):1346 [Crossref]

2- Chen M, Che C. Perceived social support, self-management, perceived stress, and post-traumatic growth in older patients following stroke: Chain mediation analysis. 2024;103(29):e38836 [Crossref]

3- Gao Y, Zhao L, Li K, Su X, Li X, Li J, Zhao Z, Wang H, He Z, Fang F, Xu W, Qian X, Fan L, Liu L. The J-shape Association between Total Bilirubin and Stroke in Older Patients with Obstructive Sleep Apnea Syndrome: A Multicenter Study. The Journal of nutrition, health and aging. 2023;27(9):692 [Crossref]

4- Zhou J, Wu Z, Qiao T, Xu H. Development of Laboratory Parameters-Based Formulas in Predicting Short Outcomes for Adult Hemophagocytic Lymphohistiocytosis Patients with Different Underlying Diseases. J Clin Immunol. 2022;42(5):1000 [Crossref]

5- Türkmen D, Bowden J, Masoli J, Melzer D, Pilling L. SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients. IJMS. 2024;25(8):4426 [Crossref]

6- Wang X, Wu D, Zhong P. Serum bilirubin and ischaemic stroke: a review of literature. Stroke Vasc Neurol. 2020;5(2):198 [Crossref]

7- Zhao K, Wang R, Chen R, Liu J, Ye Q, Wang K, Li J. Association between bilirubin levels with incidence and prognosis of stroke: A meta-analysis. Front Neurosci. 2023;17 [Crossref]

8- Sun M, Weng Y, Cheng J, Li G, Xiao Q. Higher baseline serum bilirubin levels are associated with increased risk of early neurological deterioration in women with acute ischemic stroke. Front Neurol. 2024;15 [Crossref]

9- Wang Y, Sun W, Miao J, Zhu Z, Liang W, Qiu X, Pan C, Li G, Lan Y, Zhao X, Xu Y. Nomogram including indirect bilirubin for the prediction of post-stroke depression at 3 months after mild acute ischemic stroke onset. Front Neurol. 2023;14 [Crossref]

10- Mahadevan A, Krishnakumar M, Pinnamaneni M, Desai R. Serum direct bilirubin as a prognostic marker for short-term ischemic stroke morbidity and mortality: Pooled analysis of cohort studies. Journal of the Neurological Sciences. 2024;463:123120 [Crossref]

11- Ghojazadeh M, Sagheb Asl E, Vahed N, Hassanpour R, Sanaie S, Mahmoodpoor A, Hosseini M, Soleimanpour H. Determination of the Predictive Value of Serum Bilirubin in Patients with Ischemic Stroke: A Systematic Review. Arch Neurosci. 2020;7(2) [Crossref]

12- Ouyang Q, Wang A, Tian X, Zuo Y, Liu Z, Xu Q, Meng X, Chen P, Li H, Wang Y. Serum bilirubin levels are associated with poor functional outcomes in patients with acute ischemic stroke or transient ischemic attack. BMC Neurol. 2021;21(1) [Crossref]

13- Duan H, Geng X, Ding Y. Hepatic responses following acute ischemic stroke: A clinical research update. 2023;9(2):57 [Crossref]

14- Peng Q, Bi R, Chen S, Chen J, Li Z, Li J, Jin H, Hu B. Predictive value of different bilirubin subtypes for clinical outcomes in patients with acute ischemic stroke receiving thrombolysis therapy. CNS Neurosci Ther. 2022;28(2):226 [Crossref]

15- Jia Y, Ye X, Song G, Li X, Ye J, Yang Y, Lu K, Huang S, Zhu S. Direct bilirubin: A predictor of hematoma expansion after intracerebral hemorrhage. The American Journal of Emergency Medicine. 2023;71:150 [Crossref]