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Adv Pharm Bull. 2018;8(4): 667-674. doi: 10.15171/apb.2018.075
PMID: 30607339        PMCID: PMC6311640

Research Article

Eryngium Billardieri Induces Apoptosis via Bax Gene Expression in Pancreatic Cancer Cells

Neda Roshanravan 1 ORCID, Parina Asgharian 2,3 ORCID, Hassan Dariushnejad 4 ORCID, Naimeh Mesri Alamdari 5 ORCID, Behzad Mansoori 6 ORCID, Ali Mohammadi 6 ORCID, Shahriar Alipour 7 ORCID, Meisam Barati 8 ORCID, Abed Ghavami 9 ORCID, Vajihe Ghorbanzadeh 10 ORCID, Fatemeh Aamazadeh 9 ORCID, Alireza Ostadrahimi 9 * ORCID

Cited by CrossRef: 24


1- Hawryl A, Hawryl M, Hawrył D, Chernetskyy M. The evaluation of the antioxidant activity of selected Eryngium species based on thin-layer chromatography fingerprints using chemometric tools . Journal of Liquid Chromatography & Related Technologies. 2024;47(16-20):309 [Crossref]
2- Yin X, Yang J, Chen J, Ni R, Zhou Y, Song H, Jin L, Tang T, Pan Y. LncRNA CTD-3252C9.4 modulates pancreatic cancer cell survival and apoptosis through regulating IFI6 transcription. Cancer Cell Int. 2021;21(1) [Crossref]
3- Nazeri M, Mirzaie-asl A, Saidijam M, Moradi M. Methanolic extract of Artemisia absinthium prompts apoptosis, enhancing expression of Bax/Bcl-2 ratio, cell cycle arrest, caspase-3 activation and mitochondrial membrane potential destruction in human colorectal cancer HCT-116 cells. Mol Biol Rep. 2020;47(11):8831 [Crossref]
4- Yavari S, Hekmat A, Sardari S. The ethanolic extract of Eryngium billardierei F. Delaroche restrains protein glycation in human serum albumin: an in vitro study. J Serb Chem Soc. 2024;89(9):1147 [Crossref]
5- Kikowska M, Hermosaningtyas A, Chanaj-Kaczmarek J. Little-known Saniculeae genera: phytochemical studies and pharmaceutical activities. Phytochem Rev. 2024; [Crossref]
6- Arslan A, Paşayeva L, Tugay O. Cytotoxic evaluation and LC-MS/MS analysis of aerial parts of Eryngium kotschyi Boiss. grown in Turkey. Braz J Pharm Sci. 2022;58 [Crossref]
7- Daneshzadeh M, Abbaspour H, Amjad L, Nafchi A. An investigation on phytochemical, antioxidant and antibacterial properties of extract from Eryngium billardieri F. Delaroche. Food Measure. 2020;14(2):708 [Crossref]
8- Alvarado T, Mariezcurrena Berasain M, Salem A, Pinzón Martínez D. Antimicrobial and Antioxidant Activities of Two Medicinal Plants Cuphea aequipetala var. hispida (Cav.) Koehne and Eryngium comosum Delaroche F Against Bacteria Related to Equine Infections. Journal of Equine Veterinary Science. 2020;94:103269 [Crossref]
9- Triantafillidis J, Triantafyllidi E, Sideris M, Pittaras T, Papalois A. Herbals and Plants in the Treatment of Pancreatic Cancer: A Systematic Review of Experimental and Clinical Studies. Nutrients. 2022;14(3):619 [Crossref]
10- Forouhandeh H, Rezaei Param Z, Molavi O, Asgharian P, Tarhriz V. Evaluation of anti-proliferative activity of Eryngium caucasicum on melanoma cancer cells. BMC Complement Med Ther. 2022;22(1) [Crossref]
11- Park M. Therapeutic Strategies for Pancreatic-Cancer-Related Type 2 Diabetes Centered around Natural Products. IJMS. 2023;24(21):15906 [Crossref]
12- Heidari A, Meftahi G, Bahrami F, Bahari Z, Zarei Mahmoudabadi A, Fallah Huseini H, Jangravi Z. Anti-Adipogenic Effects of Eryngium billardieri Extract during 3T3-L1 Adipocyte Differentiation. J Adv Med Biomed Res. 2023;31(147):391 [Crossref]
13- Hosseini K, Partovi Ariya M, Molavi O, Asgharian P, Tarhriz V. The Fractions of Eryngium thyrsoideum Extract Sensitize Breast Cancer Cells to Apoptosis. Jundishapur J Nat Pharm Prod. 2022;17(3) [Crossref]
14- Heydari Z, Sadeghi-Dinani M, Talebi A, Minaiyan M. Evaluation of anti-ulcerative effect of Eryngium billardieri extracts on experimental colitis in rats. Physiol Pharmacol. 2024;28(1):56 [Crossref]
15- Babich O, Samsuev I, Tsibulnikova A, Zemlyakova E, Popov A, Ivanova S, Noskova S, Sukhikh S. Properties of plant extracts and component composition: column chromatography and IR spectroscopy. 2024;12(2):373 [Crossref]
16- Haghani M, Fadaei V, Salehifar M. In vitro evaluation of milk incorporated with Eryngium billardieri Delar alcoholic extract for antioxidant and antidiabetic potentials. Food Science & Nutrition. 2024;12(10):7242 [Crossref]
17- Das G, Das S, Talukdar A, Venil C, Bose S, Banerjee S, Shin H, Gutiérrez-Grijalva E, Heredia J, Patra J. Pharmacology and Ethnomedicinal Potential of Selected Plants Species from Apiaceae (Umbelliferae). CCHTS. 2023;26(2):256 [Crossref]
18- Sukhikh S, Asyakina L, Korobenkov M, Skrypnik L, Pungin A, Ivanova S, Larichev T, Larina V, Krol O, Ulrikh E, Chupakhin E, Babich O. Chemical Composition and Content of Biologically Active Substances Found in Cotinus coggygria, Dactylorhiza maculata, Platanthera chlorantha Growing in Various Territories. Plants. 2021;10(12):2806 [Crossref]
19- Javanshir E, Ebrahimi Z, Mirzohreh S, Ghaffari S, Banisefid E, Alamdari N, Roshanravan N. Disparity of gene expression in coronary artery disease: insights from MEIS1, HIRA, and Myocardin. Mol Biol Rep. 2024;51(1) [Crossref]
20- Haji Gholami M, Riyahi Malayeri S, ziloubaf A, Hassanpour H. High intensity interval training and Eryngium billardieri extract consumption on MMP-2 gene expression of visceral fat in rats with metabolic syndrome. jspac. 2022;2(3):17 [Crossref]
21- Görmez G. The Anticancer Potential of Van Lake Basin Plants. 2024;29(2):787 [Crossref]
22- Alipour S, Pishkar L, Chaleshi V. Cytotoxic Effect of Portulaca Oleracea Extract on the Regulation of CDK1 and P53 Gene Expression in Pancreatic Cancer Cell Line. Nutrition and Cancer. 2022;74(5):1792 [Crossref]
23- Osqueei M, Mahmoudabadi A, Bahari Z, Meftahi G, Movahedi M, Taghipour R, Mousavi N, Huseini H, Jangravi Z. Eryngium billardieri extract affects cardiac gene expression of master regulators of cardiomyaopathy in rats with high fatdiet-induced insulin resistance. Clinical Nutrition ESPEN. 2023;56:59 [Crossref]