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Adv Pharm Bull. 2019;9(1): 22-37. doi: 10.15171/apb.2019.004
PMID: 31011555        PMCID: PMC6468232

Review Article

Nigella sativa and its Derivatives as Food Toxicity Protectant Agents

Zahra Karimi 1,2,3 ORCID, Adel Mirza Alizadeh 4 ORCID, Jafar Ezzati Nazhad Dolatabadi 5 * ORCID, Parvin Dehghan 2 * ORCID

Cited by CrossRef: 15


1- Hal A, El‐Barbary M. Therapeutic effect of Nigella sativa oil and ciprofloxacin against bacterial infection based on interleukin 1β expression and kidney histopathological alterations in Oreochromis niloticus . Aquaculture Research. 2021;52(6):2772 [Crossref]
2- AZİRAK S, TAŞTEMİR KORKMAZ D, BİLGİÇ S, ÖZGÖÇMEN M, ÖZER M. Thymoquinone Prevents Valproic Acid-Induced Nephrotoxicity in Rat Kidney. 2022;5(2):77 [Crossref]
3- Burdock G. Assessment of black cumin (Nigella sativa L.) as a food ingredient and putative therapeutic agent. Regulatory Toxicology and Pharmacology. 2022;128:105088 [Crossref]
4- Abd-Elkareem M, Soliman M, Abd El-Rahman M, Abou Khalil N. Effect of Nigella sativa L. Seed on the Kidney of Monosodium Glutamate Challenged Rats. Front Pharmacol. 2022;13 [Crossref]
5- Abd-Elkareem M, Abd El-Rahman M, Khalil N, Amer A. Antioxidant and cytoprotective effects of Nigella sativa L. seeds on the testis of monosodium glutamate challenged rats. Sci Rep. 2021;11(1) [Crossref]
6- Ozsan M, Hatipoglu D, Donmez H, Undag I, Donmez N. PROTECTIVE EFFECT OF Nigella sativa ON SOME HEMATOLOGICAL PARAMETERS IN RATS EXPOSED TO ACRYLAMIDE. THE JAPS. 2024;34(4):853 [Crossref]
7- Abdou N, Roby M, AL-Huqail A, Elkelish A, Sayed A, Alharbi B, Mahdy H, Abou-Sreea A. Compost Improving Morphophysiological and Biochemical Traits, Seed Yield, and Oil Quality of Nigella sativa under Drought Stress. Agronomy. 2023;13(4):1147 [Crossref]
8- Fomina D, Abdullaev S, Raeva N, Zasukhina G. A component of the Nigella sativa plant as a radioprotector and antitumor drug. Radiation biology Radioecology. 2024;64(4):351 [Crossref]
9- HATİPOĞLU D, ÖZSAN M, DÖNMEZ H, DÖNMEZ N. Hepatoprotective effects of Nigella Sativa oil against acrylamide-induced liver injury in rats. 2023;70(4):419 [Crossref]
10- Hashempour-baltork F, Mirza Alizadeh A, Taghizadeh M, Hosseini H. Cold plasma technology: A cutting-edge approach for enhancing shrimp preservation. Heliyon. 2024;10(23):e40460 [Crossref]
11- Karimi Z, Ghaffari M, Ezzati Nazhad Dolatabadi J, Dehghan P. The protective effect of thymoquinone on tert-butylhydroquinone induced cytotoxicity in human umbilical vein endothelial cells. 2019;8(6):1050 [Crossref]
12- Mirza Alizadeh A, Golzan S, Mahdavi A, Dakhili S, Torki Z, Hosseini H. Recent advances on the efficacy of essential oils on mycotoxin secretion and their mode of action. Critical Reviews in Food Science and Nutrition. 2022;62(17):4726 [Crossref]
13- Abd-Elkareem M, Soliman M, Abd El-Rahman M, Abou Khalil N. The protective effect of Nigella sativa seeds against monosodium glutamate-induced hepatic dysfunction in rats. Toxicology Reports. 2022;9:147 [Crossref]