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Adv Pharm Bull. 2019;9(2): 302-306. doi: 10.15171/apb.2019.035
PMID: 31380257        PMCID: PMC6664125

Research Article

Protective Effects of Pyruvic Acid Salt Against Lithium Toxicity and Oxidative Damage in Human Blood Mononuclear Cells

Evgenii Plotnikov 1,2 * ORCID, Innokenty Losenkov 1 ORCID, Elena Epimakhova 1 ORCID, Nikolay Bohan 1 ORCID

Cited by CrossRef: 9


1- Tang S, Liao D, Li X, Lin Y, Han S, Zheng S. Cell-Free Biosynthesis System: Methodology and Perspective of in Vitro Efficient Platform for Pyruvate Biosynthesis and Transformation. ACS Synth Biol. 2021;10(10):2417 [Crossref]
2- Tretyakova M, Krivoshchekov S, Plotnikov E, Dorozhko E, Voronova O, Larkina M, Brazovskiy K, Belousov M. Standardization of the Pharmaceutical Substance of Lithium Salt Gamma-lactone of 2,3-dehydro-l-gulonic Acid as a Radio-sensitizing Agent. Razrabotka i registraciâ lekarstvennyh sredstv. 2023;12(3):125 [Crossref]
3- Yuan W, Du Y, Yu K, Xu S, Liu M, Wang S, Yang Y, Zhang Y, Sun J. The Production of Pyruvate in Biological Technology: A Critical Review. Microorganisms. 2022;10(12):2454 [Crossref]
4- Tsai C, Hsieh S, Lu C, Wu T, Liao H, Wu C, Li K, Kuo Y, Lee H, Shen C, Yu C. Cross-Talk between Mitochondrial Dysfunction-Provoked Oxidative Stress and Aberrant Noncoding RNA Expression in the Pathogenesis and Pathophysiology of SLE. IJMS. 2019;20(20):5183 [Crossref]
5- Plotnikov E, Litvak M. Lithium ascorbate as a cerebroprotective agent in a model of ischemic stroke. Z nevrol psikhiatr im SS Korsakova. 2020;120(3):29 [Crossref]
6- Epimakhova E, Plotnikov E, Boiko A, Losenkov I. P.346 Influence of lithium pyruvate on expression of AKT/mTOR-signaling pathway proteins in mononuclear cells of patients with bipolar disorder. European Neuropsychopharmacology. 2020;40:S200 [Crossref]
7- Losenkov I, Plotnikov E, Epimakhova E, Bokhan N. Lithium in the psychopharmacology of affective disorders and mechanisms of its effects on cellular physiology. Z nevrol psikhiatr im SS Korsakova. 2020;120(11):108 [Crossref]
8- Plotnikov E, Belousov M, Brazovsky K, Larkina M, Artamonov A, Stuchebrov S, Chernov V. Experimental study of radioprotective properties of lithium pyruvate in vitro. Sib onkol ž. 2024;23(4):66 [Crossref]
9- Wang S, Yang Y, Yu K, Xu S, Liu M, Sun J, Zheng J, Zhang Y, Yuan W. Engineering of Yarrowia lipolytica for producing pyruvate from glycerol. 3 Biotech. 2022;12(4) [Crossref]
10- Plotnikov E, Pukhnyarskaya D, Chernova A. Lithium and Microorganisms: Biological Effects and Mechanisms. CPB. 2023;24(13):1623 [Crossref]
11- Nasimi Z, Momeni H, Etemadi T, Darbandi N, Babar Khawar M. In Vitro Coexposure of Silymarin with Lithium Chloride Preserves Human Sperm Quality: A Useful Approach to Reduce Oxidative Damages. Andrologia. 2023;2023:1 [Crossref]