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Adv Pharm Bull. 2020;10(3): 430-436. doi: 10.34172/apb.2020.052
PMID: 32665902        PMCID: PMC7335983

Research Article

Grape Seed Oil as a Natural Therapy in Male Rats with Alzheimer’s Diseases

Farnoosh Berahmand 1 ORCID, Golnoush Anoush 2 ORCID, Mir-Jamal Hosseini 3 ORCID, Mahdieh Anoush 4 * ORCID

Cited by CrossRef: 13


1- Jebur A, El-Sayed R, El-Demerdash F. Grape seeds: nutritional value, health advantages, and industrial applications. 2025; [Crossref]
2- Anoush M, Taghaddosi N, Bokaei Hosseini Z, Rahmati F, Bijani S, Kalantari-Hesari A, Hosseini M. Neuroprotective effects of empagliflozin against scopolamine-induced memory impairment and oxidative stress in rats. IBRO Neuroscience Reports. 2025;18:163 [Crossref]
3- Mohapatra D, Kanungo S, Pradhan S, Jena S, Prusty S, Sahu P. Captopril is more effective than Perindopril against aluminium chloride induced amyloidogenesis and AD like pathology. Heliyon. 2022;8(2):e08935 [Crossref]
4- Yang C, Shang K, Lin C, Wang C, Shi X, Wang H, Li H. Processing technologies, phytochemical constituents, and biological activities of grape seed oil (GSO): A review. Trends in Food Science & Technology. 2021;116:1074 [Crossref]
5- Kaboli Z, Hosseini M, Sadighian S, Rostamizadeh K, Hamidi M, Manjili H. Valine conjugated polymeric nanocarriers for targeted co-delivery of rivastigmine and quercetin in rat model of Alzheimer disease. International Journal of Pharmaceutics. 2023;645:123418 [Crossref]
6- Saeni Z, Asle Rousta M, Amini R. The Effect of Grape Seed Oil and Vitamin E on Learning, Spatial Memory, and Anxiety Behaviors in Rats Exposed to Social Isolation. SJKU. 2024;29(3):1 [Crossref]
7- Martin M, Grao-Cruces E, Millan-Linares M, Montserrat-de la Paz S. Grape (Vitis vinifera L.) Seed Oil: A Functional Food from the Winemaking Industry. Foods. 2020;9(10):1360 [Crossref]
8- Parande F, Dave A, Park E, McAllister C, Pezzuto J. Effect of Dietary Grapes on Female C57BL6/J Mice Consuming a High-Fat Diet: Behavioral and Genetic Changes. Antioxidants. 2022;11(2):414 [Crossref]
9- Aziz N, Wal P, Patel A, Prajapati H. A comprehensive review on the pharmacological role of gut microbiome in neurodegenerative disorders: potential therapeutic targets. Naunyn-Schmiedeberg's Arch Pharmacol. 2024;397(10):7307 [Crossref]
10- Mahdipour R, Ebrahimzadeh-Bideskan A, Hosseini M, Shahba S, Lombardi G, Malvandi A, Mohammadipour A. The benefits of grape seed extract in neurological disorders and brain aging. Nutritional Neuroscience. 2023;26(5):369 [Crossref]
11- Gates E, Bernath A, Klegeris A. Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases. 2022;33(7):767 [Crossref]
12- Ferrer-Gallego R, Silva P. The Wine Industry By-Products: Applications for Food Industry and Health Benefits. Antioxidants. 2022;11(10):2025 [Crossref]
13- Kazmi I, Afzal M, Imam F, Alzarea S, Patil S, Mhaiskar A, Shah U, Almalki W. Barbaloin’s Chemical Intervention in Aluminum Chloride Induced Cognitive Deficits and Changes in Rats through Modulation of Oxidative Stress, Cytokines, and BDNF Expression. ACS Omega. 2024;9(6):6976 [Crossref]
14- Tian M, Bai Y, Tian H, Zhao X. The Chemical Composition and Health-Promoting Benefits of Vegetable Oils—A Review. Molecules. 2023;28(17):6393 [Crossref]