Mucoadhesive Multiparticulate Drug Delivery Systems: An Extensive Review of Patents

Someshwar Komati ¹ * , Suryakanta Swain ², Muddana Eswara Bhanoji Rao ³, Bikash Ranjan Jena ², Vishali Dasi ¹

Cited by CrossRef: 16

1- Vieira W, da Silva M, de Oliveira Nascimento L, Vieira M. k-Carrageenan/sericin-based multiparticulate systems: A novel gastro-resistant polymer matrix for indomethacin delivery. International Journal of Biological Macromolecules. 2023;232:123381 [Crossref]

2- Szekalska M, Citkowska A, Wróblewska M, Winnicka K. The Impact of Gelatin on the Pharmaceutical Characteristics of Fucoidan Microspheres with Posaconazole. Materials. 2021;14(15):4087 [Crossref]

3- Sharma R, Kumar S, Malviya R, Prajapati B, Puri D, Limmatvapirat S, Sriamornsak P. Recent advances in biopolymer-based mucoadhesive drug delivery systems for oral application. Journal of Drug Delivery Science and Technology. 2024;91:105227 [Crossref]

4- Guerini M, Condrò G, Perugini P. Evaluation of the Mucoadhesive Properties of Chitosan-Based Microstructured Lipid Carrier (CH-MLC). Pharmaceutics. 2022;14(1):170 [Crossref]

5- Puri V, Sharma A, Kumar P, Singh I. Thiolation of Biopolymers for Developing Drug Delivery Systems with Enhanced Mechanical and Mucoadhesive Properties: A Review. Polymers. 2020;12(8):1803 [Crossref]

6- Rohani Shirvan A, Hemmatinejad N, Bahrami S, Bashari A. Fabrication of multifunctional mucoadhesive buccal patch for drug delivery applications. J Biomedical Materials Res. 2021;109(12):2640 [Crossref]

7- Cazorla-Luna R, Martín-Illana A, Notario-Pérez F, Ruiz-Caro R, Veiga M. Naturally Occurring Polyelectrolytes and Their Use for the Development of Complex-Based Mucoadhesive Drug Delivery Systems: An Overview. Polymers. 2021;13(14):2241 [Crossref]

8- da Silva J, dos Santos R, Vecchi C, Bruschi M. Drug Delivery Platforms Containing Thermoresponsive Polymers and Mucoadhesive Cellulose Derivatives: A Review of Patents. RADDF. 2022;16(2):90 [Crossref]

9- Vieira W, Nicollini M, da Silva M, de Oliveira Nascimento L, Vieira M. Natural polysaccharides and proteins applied to the development of gastroresistant multiparticulate systems for anti-inflammatory drug delivery – A systematic review. European Polymer Journal. 2022;172:111205 [Crossref]

10- Vieira W, da Silva M, de Oliveira Nascimento L, Vieira M. Development and characterization of crosslinked k-carrageenan/sericin blend with covalent agents or thermal crosslink for indomethacin extended release. International Journal of Biological Macromolecules. 2023;246:125558 [Crossref]

11- dos Santos Ramos M, dos Santos K, da Silva P, de Toledo L, Marena G, Rodero C, de Camargo B, Fortunato G, Bauab T, Chorilli M. Nanotechnological strategies for systemic microbial infections treatment: A review. International Journal of Pharmaceutics. 2020;589:119780 [Crossref]

12- Giannini G, Ragusa I, Nardone G, Soldi S, Elli M, Valenti P, Rosa L, Marra E, Stoppoloni D, Merlo Pich E, Isola G. Probiotics-Containing Mucoadhesive Gel for Targeting the Dysbiosis Associated with Periodontal Diseases. International Journal of Dentistry. 2022;2022:1 [Crossref]

13- Moles-Aranda C, Pérez-González N, Calpena-Campmany A, Martín-Villena M, Otero-Espinar F, Severino P, Souto E, Morales-Molina J, Clares-Naveros B. Preparation and ex vivo investigation of an injectable microparticulate formulation for gastrointestinal mucosa polyp resection. European Journal of Pharmaceutics and Biopharmaceutics. 2022;178:25 [Crossref]

14- Yang W, Bhattachar S, Patel P, Landis M, Patel D, Reid D, Duvnjak Romic M. Modulating target engagement of small molecules via drug delivery: approaches and applications in drug discovery and development. Drug Discovery Today. 2021;26(3):713 [Crossref]

15- Sonawane P, Sonawane P, Shelar H, Dashpute S, Kalam A. Review on Mucoadhesive Drug Delivery System. SSRN Journal. 2023; [Crossref]

16- Chen W, Wainer J, Ryoo S, Qi X, Chang R, Li J, Lee S, Min S, Wentworth A, Collins J, Tamang S, Ishida K, Hayward A, Langer R, Traverso G. Dynamic omnidirectional adhesive microneedle system for oral macromolecular drug delivery. Sci Adv. 2022;8(1) [Crossref]

17- Sugio C, Garcia A, Kitamoto K, Santiago Júnior J, Soares S, Porto V, Urban V, Ferrari P, Fernandes M, Neppelenbroek K. Mucoadhesive delivery systems for oral candidiasis treatment: A systematic review and meta‐analysis. Oral Diseases. 2024; [Crossref]

18- Szekalska M, Wróblewska M, Czajkowska-Kośnik A, Sosnowska K, Misiak P, Wilczewska A, Winnicka K. The Spray-Dried Alginate/Gelatin Microparticles with Luliconazole as Mucoadhesive Drug Delivery System. Materials. 2023;16(1):403 [Crossref]