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Freq.: Quarterly

eISSN: 2251-7308 
pISSN: 2228-5881 

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Adv Pharm Bull. 2019;9(2): 321-324. doi: 10.15171/apb.2019.038
PMID: 31380260        PMCID: PMC6664109

Short Communication

The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia

Vahideh Ebrahimzadeh Attari 1 ORCID, Mohammad Hosein Somi 2 ORCID, Mohammad Asghari Jafarabadi 3 ORCID, Alireza Ostadrahimi 4 * ORCID, Seyed-Yaghob Moaddab 2 ORCID, Neda Lotfi 4,5 ORCID

Cited by CrossRef: 18

1- Schulz C, Kupčinskas J. Review ‐ Helicobacter pylori and non‐malignant upper gastro‐intestinal diseases. Helicobacter. 2020;25(S1) [Crossref]
2- Sousa C, Ferreira R, Azevedo N, Oleastro M, Azeredo J, Figueiredo C, Melo L. Helicobacter pylori infection: from standard to alternative treatment strategies. Critical Reviews in Microbiology. 2022;48(3):376 [Crossref]
3- Magdy H, Rady M, Salama M, Sayed H, Hamza D, Azzam M, Essa E. Isolation of Multidrug-Resistant Helicobacter pylori from Wild Houseflies Musca domestica with a New Perspective for the Treatment. Vector-Borne and Zoonotic Diseases. 2023;23(2):63 [Crossref]
4- Foshati S, Poursadeghfard M, Heidari Z, Amani R. The effects of ginger supplementation on common gastrointestinal symptoms in patients with relapsing-remitting multiple sclerosis: a double-blind randomized placebo-controlled trial. BMC Complement Med Ther. 2023;23(1) [Crossref]
5- Saeed M, Eghdami A. Inhibitory Effect of Herbal Compounds on the Oxygen-Insensitive NADPH Nitro Reductase Enzyme of Metronidazole-Resistant Helicobacter pylori. sciphy. 2023;2(1):77 [Crossref]
6- Verma P, Singh B, Sharma P, Tukra S, Aït-Kaddour A, Bhat Z. Mechanistic advances and therapeutic applications of Zingiber officinale Roscoe. Food Chemistry Advances. 2025;8:101060 [Crossref]
7- Hameed H, Hussain J, Cláudia Paiva-Santos A, Zaman M, Hamza A, Sajjad I, Asad F. Comprehensive insights on treatment modalities with conventional and herbal drugs for the treatment of duodenal ulcers. Naunyn-Schmiedeberg's Arch Pharmacol. 2024;397(11):8211 [Crossref]
8- Jalalpour S, Mirzaee V, Taheri M, Sheikh Fathollahi M, Khorramdelazad H, Jafarzadeh A. Ginger Extract Modulates the Production of Chemokines CCL17, CCL20, CCL22, and CXCL10 and the Gene Expression of Their Receptors in Peripheral Blood Mononuclear Cells from Peptic Ulcer Patients Infected with Helicobacter pylori. Jundishapur J Nat Pharm Prod. 2021;16(3) [Crossref]
9- Niakan M, Johari H, Shariati M, Moghadamnia D, Talebi E. Protective activity of hydroalcoholic extract of zingiber officinale rosc. on doxorubicin-induced hepatic toxicity in male rats. mljgoums. 2023;17(4):9 [Crossref]
10- Elsaadany M, AlTwejry H, Zabran R, AlShuraim S, AlShaia W, Abuzaid O, AlBaker W. Antihyperglycemic Effect of Fenugreek and Ginger in Patients with Type 2 Diabetes: A Double-Blind, Placebo-controlled Study. CNF. 2022;18(2):231 [Crossref]
11- Pasalar M, Daneshfard B, Bagheri Lankarani K. Jollab: A Safe Remedy for Functional Dyspepsia in Persian Medicine. Adv Pharm Bull. 2020;11(1):8 [Crossref]
12- Sinha A, Das S, Mazumder A. Healing the Gut Naturally: Exploring Herbal Remedies for Functional Gastrointestinal Disorders. JNR. 2025;:1575 [Crossref]
13- Ahmad W. The Zingiber Officinale Roscoe Combat Helicobacter Pylori Infection in Human Gastrointestinal Tract Diagnosis and Treatment. PJHS. 2022;:13 [Crossref]
14- Cardos I, Zaha D, Sindhu R, Cavalu S. Revisiting Therapeutic Strategies for H. pylori Treatment in the Context of Antibiotic Resistance: Focus on Alternative and Complementary Therapies. Molecules. 2021;26(19):6078 [Crossref]
15- Lu Q, Wang J, Tang Y, Li W, Li C. Phytochemical analysis of dried ginger extract and its inhibitory effect and mechanism on Helicobacter pylori and associated ureases. Food Funct. 2025;16(3):1100 [Crossref]
16- Maniziia S, Gupta O, Kalita S, Kalita R. CLINICAL STUDY TO EVALUATE THE EFFICACY OF VIDANGA CHURNA IN THE MANAGEMENT OF URDHWAGA AMLAPITTA DUE TO HELICOBACTER PYLORI. IAMJ. 2023;p7(6):521 [Crossref]
17- Razak A, Zakaria S, Abdul Sani N, Ab Rani N, Hakimi N, Mohd Said M, Tan J, Gan H, Mad Nordin M, Makpol S. A subcritical water extract of soil grown Zingiber officinale Roscoe: Comparative analysis of antioxidant and anti-inflammatory effects and evaluation of bioactive metabolites. Front Pharmacol. 2023;14 [Crossref]
18- Nirankari R, Junker J. Does ginger relieve symptoms of dyspepsia?. EBPR. 2021;24(12):34 [Crossref]
19- Schulz R, Ahuja N, Slavin J. Effectiveness of Nutritional Ingredients on Upper Gastrointestinal Conditions and Symptoms: A Narrative Review. Nutrients. 2022;14(3):672 [Crossref]
20- Latif A, Ahmad H, Bashir I. Comparative Study on the Prokinetic Effects of Ginger, Caraway, and Peppermint in Relieving Gastrointestinal Disturbances in Pulmonary TB Patients: A Clinical Trial. Food Science & Nutrition. 2025;13(6) [Crossref]