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Adv Pharm Bull. 2019;9(3): 393-400. doi: 10.15171/apb.2019.046
PMID: 31592432        PMCID: PMC6773936

Research Article

Preparation, Physicochemical Characterization and Oxidative Stability of Omega-3 Fish Oil/α-Tocopherol-co-Loaded Nanostructured Lipidic Carriers

Yaser Shahparast 1, Masoud Eskandani 2, Ahmad Rajaei 1, Ahmad Yari Khosroushahi 3,4 * ORCID

Cited by CrossRef: 18


1- Miyazawa T, Itaya M, Burdeos G, Nakagawa K, Miyazawa T. A Critical Review of the Use of Surfactant-Coated Nanoparticles in Nanomedicine and Food Nanotechnology. IJN. 2021;Volume 16:3937 [Crossref]
2- Chang C, Li X, Zhai J, Su Y, Gu L, Li J, Yang Y. Stability of protein particle based Pickering emulsions in various environments: Review on strategies to inhibit coalescence and oxidation. Food Chemistry: X. 2023;18:100651 [Crossref]
3- Blanco-Llamero C, Fonseca J, Durazzo A, Lucarini M, Santini A, Señoráns F, Souto E. Nutraceuticals and Food-Grade Lipid Nanoparticles: From Natural Sources to a Circular Bioeconomy Approach. Foods. 2022;11(15):2318 [Crossref]
4- Ardhi A, Raharjo S, Sudjarwo W, Schreiner M. Oxidative stability of optimized nanostructured lipid carriers containing thymoquinone‐rich oil. J Americ Oil Chem Soc. 2024; [Crossref]
5- Rehman A, Jafari S, Karim A, Rasheed H, Assadpour E, Virk M, Liang Q, Suleria H, Gan R, Ren X. Ultrasonically Prepared Biopolymeric Multifunctional Nanocarriers for Encapsulating Dietary Oils: Recent Developments and Food Applications. Food Bioprocess Technol. 2024;17(12):4537 [Crossref]
6- Erdoğan Ü, Gökçe E. Fig seed oil‐loaded nanostructured lipid carriers: Evaluation of the protective effects against oxidation. J Food Process Preserv. 2021;45(10) [Crossref]
7- Tabatabaei M, Ebrahimi B, Rajaei A, Movahednejad M, Rastegari H, Taghavi E, Aghbashlo M, Gupta V, Lam S. Producing submicron chitosan-stabilized oil Pickering emulsion powder by an electrostatic collector-equipped spray dryer. Carbohydrate Polymers. 2022;294:119791 [Crossref]
8- Ahmed O, Fahmy U, Bakhaidar R, El-Moselhy M, Okbazghi S, Ahmed A, Hammad A, Alhakamy N. RETRACTED: Omega-3 Self-Nanoemulsion Role in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats. Pharmaceutics. 2020;12(2):140 [Crossref]
9- Ahmad M, Ahmad J, Zafar S, Warsi M, Abdel-Wahab B, Akhter S, Alam M. Omega-3 Fatty Acids As Adjunctive Therapeutics: Prospective of Nanoparticles in Its Formulation Development. Ther Deliv. 2020;11(1):851 [Crossref]
10- Ferreira D, Rodrigues C, Coimbra J, de Oliveira E. Delivery and controlled release abilities of chitosan/carboxymethylcellulose micropolyelectrolyte complexes (PECs) toward niacinamide (vitamin B3). International Journal of Biological Macromolecules. 2024;283:137848 [Crossref]
11- Wang Y, Rehman A, Jafari S, Shehzad Q, Yu L, Su Y, Wu G, Jin Q, Zhang H, Suleria H, Wang X. Micro/nano-encapsulation of marine dietary oils: A review on biomacromolecule-based delivery systems and their role in preventing cardiovascular diseases. International Journal of Biological Macromolecules. 2024;261:129820 [Crossref]
12- Blanco-Llamero C, Galindo-Camacho R, Fonseca J, Santini A, Señoráns F, Souto E. Development of Lipid Nanoparticles Containing Omega-3-Rich Extract of Microalga Nannochlorpsis gaditana. Foods. 2022;11(23):3749 [Crossref]
13- Shakeri M, Ghobadi R, Sohrabvandi S, Khanniri E, Mollakhalili-Meybodi N. Co-encapsulation of omega-3 and vitamin D3 in beeswax solid lipid nanoparticles to evaluate physicochemical and in vitro release properties. Front Nutr. 2024;11 [Crossref]
14- Nguyen V, Thuy V, Van T, Dao A, Lee B. Nanostructured lipid carriers and their potential applications for versatile drug delivery via oral administration. OpenNano. 2022;8:100064 [Crossref]
15- Zheng L, Xu H, Zhang H, Shi C, Zhou W, Zhang X. Nanostructured lipid carrier as a strategy for encapsulation of formononetin and perilla seed oil: In vitro characterization and stability studies. Food Bioscience. 2023;53:102707 [Crossref]
16- Homroy S, Chopra R, Singh P, Dhiman A, Chand M, Talwar B. Role of encapsulation on the bioavailability of omega‐3 fatty acids. Comp Rev Food Sci Food Safe. 2024;23(1) [Crossref]
17- Saghafi Z, Mohammadi M, Mahboobian M, Derakhshandeh K. Preparation, characterization, and in vivo evaluation of perphenazine-loaded nanostructured lipid carriers for oral bioavailability improvement. Drug Development and Industrial Pharmacy. 2021;47(3):509 [Crossref]