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Adv Pharm Bull. 2019;9(2): 271-280. doi: 10.15171/apb.2019.031
PMID: 31380253        PMCID: PMC6664121

Research Article

Omega-3 Fatty Acid Based Nanolipid Formulation of Atorvastatin for Treating Hyperlipidemia

Revathy Sreedhar 1 ORCID, Vrinda Sasi Kumar 1 ORCID, Anil Kumar Bhaskaran Pillai 2 ORCID, Sabitha Mangalathillam 1 * ORCID

Cited by CrossRef: 19


1- Shehata T, Khalil H, Elsewedy H, Soliman W. Myrrh essential oil-based nanolipid formulation for enhancement of the antihyperlipidemic effect of atorvastatin. Journal of Drug Delivery Science and Technology. 2021;61:102277 [Crossref]
2- Singh S, Zahoor I, Sharma N, Behl T, Kanojia N, Sehgal A, Mohan S, Almoshari Y, Salawi A, Aleya L, Bungau S. Insights into the pivotal role of statins and its nanoformulations in hyperlipidemia. Environ Sci Pollut Res. 2022;29(51):76514 [Crossref]
3- de Oliveira A, de Araújo R, da Silva T, da Cruz M, dos Santos V, Medeiros E, de Sousa M, de Araújo Alves K, Soares N, de Lima J, Ribeiro W. Characterization of Individual Microalgae Subparticles and as Edible Coatings. Food Biophysics. 2025;20(1) [Crossref]
4- R. Gardouh A, M. Nasef A, Mostafa Y, Gad S. Impact on HDL and LDL of Hyperlipidemic Rat Models: Designed Solid Self-Nanoemulsifying Drug Delivery Systems with Atorvastatin and Ezetimibe combination. RJPT. 2022;:2459 [Crossref]
5- Kaewmalun S, Yata T, Kitiyodom S, Yostawonkul J, Namdee K, Kamble M, Pirarat N. Clove Oil-Nanostructured Lipid Carriers: A Platform of Herbal Anesthetics in Whiteleg Shrimp (Penaeus vannamei). Foods. 2022;11(20):3162 [Crossref]
6- Gill R, Al-Badr M, Alghouti M, Mohamed N, Abou-Saleh H, Rahman M. Revolutionizing Cardiovascular Health with Nano Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach. Marine Drugs. 2024;22(6):256 [Crossref]
7- Gu Y, Shuai L, Li D, Song M, Liu Y, Yang X. Characterization of the daucosterol–lecithin complex and its impact on lipid metabolism in hyperlipidemic mice. RSC Adv. 2024;14(37):27354 [Crossref]
8- Nistor M, Rugina D, Diaconeasa Z, Socaciu C, Socaciu M. Pentacyclic Triterpenoid Phytochemicals with Anticancer Activity: Updated Studies on Mechanisms and Targeted Delivery. IJMS. 2023;24(16):12923 [Crossref]
9- Patted P, Masareddy R, Patil A, Kanabargi R, Bhat C. Omega-3 fatty acids: a comprehensive scientific review of their sources, functions and health benefits. Futur J Pharm Sci. 2024;10(1) [Crossref]
10- Domingues I, Leclercq I, Beloqui A. Nonalcoholic fatty liver disease: Current therapies and future perspectives in drug delivery. Journal of Controlled Release. 2023;363:415 [Crossref]
11- Victor F, Rehman K, Akash M, Rasheed S, Imran M, Assiri M. Technological Advancement in ω-3 Fatty Acids: Their Therapeutic Functions and Novel Delivery Strategies. CPD. 2023;29(12):893 [Crossref]
12- Kumar V, KP V, M S. Anticonvulsant and acute toxicity evaluation of phenytoin sodium–loaded polymeric nanomicelle in MES rat model. J Nanopart Res. 2022;24(8) [Crossref]
13- Amer R, Yassin G, Mohamed R, Fayez A. Pharmaceutical and Pharmacological Evaluation of the Effect of Nano-Formulated Spironolactone and Progesterone on Inflammation and Hormonal Levels for Managing Hirsutism Experimentally Induced in Rats. AAPS PharmSciTech. 2021;22(5) [Crossref]
14- Manners N, Priya V, Mehata A, Rawat M, Mohan S, Makeen H, Albratty M, Albarrati A, Meraya A, Muthu M. Theranostic Nanomedicines for the Treatment of Cardiovascular and Related Diseases: Current Strategies and Future Perspectives. Pharmaceuticals. 2022;15(4):441 [Crossref]
15- Ahmed O, Fahmy U, Bakhaidar R, El-Moselhy M, Okbazghi S, Ahmed A, Hammad A, Alhakamy N. RETRACTED: Omega-3 Self-Nanoemulsion Role in Gastroprotection against Indomethacin-Induced Gastric Injury in Rats. Pharmaceutics. 2020;12(2):140 [Crossref]
16- Ahmad M, Ahmad J, Zafar S, Warsi M, Abdel-Wahab B, Akhter S, Alam M. Omega-3 Fatty Acids As Adjunctive Therapeutics: Prospective of Nanoparticles in Its Formulation Development. Ther Deliv. 2020;11(1):851 [Crossref]