Positive Effects of PI3K/Akt Signaling Inhibition on PTEN and P53 in Prevention of Acute Lymphoblastic Leukemia Tumor Cells

Elahe Naderali ^1,2 , Behnaz Valipour ¹ , Amir Afshin Khaki ² , Jafar Soleymani Rad ², Alireza Alihemmati ² , Mohammad Rahmati ³ , Hojjatollah Nozad Charoudeh ¹ *

Cited by CrossRef: 14

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9- Holz C, Lange S, Sekora A, Knuebel G, Krohn S, Murua Escobar H, Junghanss C, Richter A. Combined BCL-2 and PI3K/AKT Pathway Inhibition in KMT2A-Rearranged Acute B-Lymphoblastic Leukemia Cells. IJMS. 2023;24(2):1359 [Crossref]

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12- Shi X, Li S, Tang S, Lu Y. Anlotinib Inhibits Proliferation and Induces Apoptosis in B-cell Acute Lymphoblastic Leukemia by Targeting the BTK and AKT/mTOR Pathway. ACAMC. 2023;23(12):1397 [Crossref]

13- Perry J, Genenger B, Thind A, Ashford B, Ranson M. PIK Your Poison: The Effects of Combining PI3K and CDK Inhibitors against Metastatic Cutaneous Squamous Cell Carcinoma In Vitro. Cancers. 2024;16(2):370 [Crossref]

14- Sun C, Wen K, Zhang B, Dong Y, Chen C, Neo S, Leng B, Gao T, Wu J. DSC2 suppresses the growth of gastric cancer through the inhibition of nuclear translocation of γ-catenin and PTEN/PI3K/AKT signaling pathway. Aging. 2023;15(13):6380 [Crossref]

15- Sommariva S, Caviglia G, Ravera S, Frassoni F, Benvenuto F, Tortolina L, Castagnino N, Parodi S, Piana M. Computational quantification of global effects induced by mutations and drugs in signaling networks of colorectal cancer cells. Sci Rep. 2021;11(1) [Crossref]