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Adv Pharm Bull. 2019;9(3): 481-489. doi: 10.15171/apb.2019.057
PMID: 31592119        PMCID: PMC6773930

Research Article

Evaluation of the Cytotoxic and Apoptogenic Effects of Glabridin and Its Effect on Cytotoxicity and Apoptosis Induced by Doxorubicin Toward Cancerous Cells

Masoud Modarresi 1 ORCID, Marziyeh Hajialyani 1 ORCID, Narges Moasefi 2 ORCID, Farahnaz Ahmadi 1 ORCID, Leila Hosseinzadeh 1 * ORCID

Cited by CrossRef: 9


1- Li C, Li T, Zhu M, Lai J, Wu Z. Pharmacological properties of glabridin (a flavonoid extracted from licorice): A comprehensive review. Journal of Functional Foods. 2021;85:104638 [Crossref]
2- Alam A, Khan M, Mathur Y, Sulaimani M, Farooqui N, Ahmad S, Nadeem A, Yadav D, Mohammad T. Structure-based identification of potential inhibitors of ribosomal protein S6 kinase 1, targeting cancer therapy: a combined docking and molecular dynamics simulations approach. Journal of Biomolecular Structure and Dynamics. 2024;42(11):5758 [Crossref]
3- Abbassi A, Yaghmaei P, Hosseinzadeh L. Cinnamaldehyde potentiates cytotoxic and apoptogenic effects of doxorubicin in prostate cancer cell line. 2024;19(4):425 [Crossref]
4- Wang Z, Ban J, Wang H, Qie R, Zhou Y. Deciphering the mechanism of Ephedra Herba-Armeniacae Semen Amarum herb pairs on COVID-19 by integrated network pharmacology and bioinformatics. Arabian Journal of Chemistry. 2024;17(2):105540 [Crossref]
5- Lin S, Lin C, Chen C, Tseng F, Wu T, Weng L, Weng C. Doxorubicin metabolism moderately attributes to putative toxicity in prodigiosin/doxorubicin synergism in vitro cells. Mol Cell Biochem. 2020;475(1-2):119 [Crossref]
6- Müllerová M, Maciel D, Nunes N, Wrobel D, Stofik M, Červenková Št́astná L, Krupková A, Cuřínová P, Nováková K, Božík M, Malý M, Malý J, Rodrigues J, Strašák T. Carbosilane Glycodendrimers for Anticancer Drug Delivery: Synthetic Route, Characterization, and Biological Effect of Glycodendrimer–Doxorubicin Complexes. Biomacromolecules. 2022;23(1):276 [Crossref]
7- Zhang J, Wu X, Zhong B, Liao Q, Wang X, Xie Y, He X. Review on the Diverse Biological Effects of Glabridin. DDDT. 2023;Volume 17:15 [Crossref]
8- Li C, Wang Y, Zhang W, Yang X, Wang Y, Hou G, Wang D, Han B, Zhang Y. The antitumor mechanisms of glabridin and drug delivery strategies for enhancing its bioavailability. Front Oncol. 2024;14 [Crossref]
9- Zhang C, Meng S, Shao Q, Wang X, Li C, Chen W, Li Y, Huang S, Ma Y. Protective effects of monoammonium glycyrrhizinate on fatty deposit degeneration induced in primary calf hepatocytes by sodium oleate administration in vitro. Research in Veterinary Science. 2022;150:213 [Crossref]
10- Pan H, Qiu H, Zhang K, Zhang P, Liang W, Yang M, Mou C, Lin M, He M, Xiao X, Zhang D, Wang H, Liu F, Li Y, Jin H, Yan X, Liang H, Cui W. Fascaplysin Derivatives Are Potent Multitarget Agents against Alzheimer’s Disease: in Vitro and in Vivo Evidence. ACS Chem Neurosci. 2019;10(11):4741 [Crossref]