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Adv Pharm Bull. 2020;10(3): 423-429. doi: 10.34172/apb.2020.051
PMID: 32665901        PMCID: PMC7335995

Research Article

Design, Synthesis and Biological Evaluation of Novel Piperazinone Derivatives as Cytotoxic Agents

Saeed Ghasemi 1 ORCID, Simin Sharifi 2, Javid Shahbazi Mojarrad 3 * ORCID

Cited by CrossRef: 7


1- Kumari N, Yadav A, Sankpal S, Murugavel S, Lakshmanan D, Kant R. Synthesis, crystal structure, quantum chemical computation and molecular docking analysis of 1-(4(tert-butyl)-4-methoxy-[1,1-biphenyl]-4-yl) ethenone. J IRAN CHEM SOC. 2024;21(6):1669 [Crossref]
2- Azmian Moghadam F, Evazalipour M, Kefayati H, Ghasemi S. 6,7-Disubstituted-4-anilinoquinazoline: Design, Synthesis and Anticancer Activity as a Novel Series of Potent Anticancer Agents . Pharm Sci. 2020;27(2):209 [Crossref]
3- Azmian Moghadam F, Dabirian S, Ebrahimi Tavani A, Alipour P, Mojabi M, Evazalipour M, Yousefbeyk F, Ghasemi S. Application of a Deep Eutectic Solvent for the Synthesis of Novel Imidazole-Containing Quinazoline Derivatives as Potent Cytotoxic Agents . Pharm Sci. 2024;30(2):215 [Crossref]
4- Yousefbeyk F, Dabirian S, Ghanbarzadeh S, Eghbali Koohi D, Yazdizadeh P, Ghasemi S. Green synthesis of silver nanoparticles from Stachys byzantina K. Koch: characterization, antioxidant, antibacterial, and cytotoxic activity. Particulate Science and Technology. 2022;40(2):219 [Crossref]
5- Moghadam F, Dabirian S, Dogaheh M, Mojabi M, Yousefbeyk F, Ghasemi S. Novel 4-Anilinoquinazoline Derivatives as Potent Anticancer Agents: Design, Synthesis, Cytotoxic Activity, and Docking Study. Aust J Chem. 2021;74(10):730 [Crossref]
6- Xia M, Yu L, Yan Z, Wang Y, Zhang L, Miao G, Li S. FTase inhibitors and cancer: prospects for use in targeted therapies. Med Chem Res. 2024;33(1):21 [Crossref]
7- Zarenezhad E, Behmard E, Karami R, Behrouz S, Marzi M, Ghasemian A, Soltani Rad M. The antibacterial and anti-biofilm effects of novel synthetized nitroimidazole compounds against methicillin-resistant Staphylococcus aureus and carbapenem-resistant Escherichia coli and Klebsiella pneumonia in vitro and in silico. BMC Chemistry. 2024;18(1) [Crossref]
8- Yu L, Wang Y, Yan Z, Zhang L, Li S. Development of erythrina-based PARP-1/FTase dual-target inhibitors against lung cancer epithelial-mesenchymal transition (EMT) in vivo and in vitro. Bioorganic Chemistry. 2024;148:107480 [Crossref]