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Adv Pharm Bull. 2020;10(3): 458-463. doi: 10.34172/apb.2020.056
PMID: 32665906        PMCID: PMC7335991

Research Article

Activation of PPARγ Inhibits TLR4 Signal Transduction Pathway in Melanoma Cancer In Vitro

Nasim Dana 1 ORCID, Golnaz Vaseghi 2,1 ORCID, Shaghayegh Haghjooy Javanmard 1 * ORCID

Cited by CrossRef: 14


1- Nascimento M, Cordeiro R, Abreu C, Santos C, Peixoto F, Duarte G, Cardoso T, de Oliveira C, Carvalho E, Carvalho L. Pioglitazone, a Peroxisome Proliferator-Activated Receptor-γ Agonist, Downregulates the Inflammatory Response in Cutaneous Leishmaniasis Patients Without Interfering in Leishmania braziliensis Killing by Monocytes. Front Cell Infect Microbiol. 2022;12 [Crossref]
2- Rahimi A, Malakoutikhah Z, Rahimmanesh I, Ferns G, Nedaeinia R, Ishaghi S, Dana N, Haghjooy Javanmard S. The nexus of natural killer cells and melanoma tumor microenvironment: crosstalk, chemotherapeutic potential, and innovative NK cell-based therapeutic strategies. Cancer Cell Int. 2023;23(1) [Crossref]
3- Pourhadi M, Ghasemi A, Abediny R, Haghjooy Javanmard S, Vaseghi G. The Inhibitory Effects of Vanillin on the Growth of Melanoma by Reducing Nuclear Factor-κB Activation. 2022;11(1):68 [Crossref]
4- Zhang X, Li X, Xiong G, Yun F, Feng Y, Ni Q, Wu N, Yang L, Yi Z, Zhang Q, Yang Z, Kuang Y, Sai B, Zhu Y. Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway. Metabolites. 2022;12(11):1132 [Crossref]
5- Haghighi E, Abolmaali S, Dehshahri A, Mousavi Shaegh S, Azarpira N, Tamaddon A. Navigating the intricate in-vivo journey of lipid nanoparticles tailored for the targeted delivery of RNA therapeutics: a quality-by-design approach. J Nanobiotechnol. 2024;22(1) [Crossref]
6- Vaseghi G, Dana N, Ghasemi A, Abediny R, Laher I, Javanmard S. Morphine promotes migration and lung metastasis of mouse melanoma cells. Brazilian Journal of Anesthesiology (English Edition). 2023;73(4):441 [Crossref]
7- Zheng Y, Liu Z, Yang X, Liu L, Ahn K. An updated review on the potential antineoplastic actions of oleuropein. Phytotherapy Research. 2022;36(1):365 [Crossref]
8- Yamamoto T, Yuan H, Suzuki S, Nemoto E, Saito M, Yamada S. Procyanidin B2 enhances anti-inflammatory responses of periodontal ligament cells by inhibiting the dominant negative pro-inflammatory isoforms of peroxisome proliferator-activated receptor γ. Journal of Dental Sciences. 2024;19(3):1801 [Crossref]
9- Asrar A, Sobhani Z, Behnam M. Melanoma Cancer Therapy Using PEGylated Nanoparticles and Semiconductor Laser. Adv Pharm Bull. 2022;12(3):524 [Crossref]
10- Vaseghi G, Ghasemi A, Laher I, Alaei H, Dana N, Naji esfahani H, Javanmard S. Morphine upregulates Toll-like receptor 4 expression and promotes melanomas in mice. Immunopharmacology and Immunotoxicology. 2023;45(3):347 [Crossref]
11- Kiaie S, Majidi Zolbanin N, Ahmadi A, Bagherifar R, Valizadeh H, Kashanchi F, Jafari R. Recent advances in mRNA-LNP therapeutics: immunological and pharmacological aspects. J Nanobiotechnol. 2022;20(1) [Crossref]
12- Leo M, Muccillo L, Dugo L, Bernini R, Santi L, Sabatino L. Polyphenols Extracts from Oil Production Waste Products (OPWPs) Reduce Cell Viability and Exert Anti-Inflammatory Activity via PPARγ Induction in Colorectal Cancer Cells. Antioxidants. 2022;11(4):624 [Crossref]
13- Dana N, Ferns G, Nedaeinia R, Haghjooy Javanmard S. Leptin signaling in breast cancer and its crosstalk with peroxisome proliferator-activated receptors α and γ. Clin Transl Oncol. 2022;25(3):601 [Crossref]