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Adv Pharm Bull. 2019;9(4): 539-558. doi: 10.15171/apb.2019.063
PMID: 31857958        PMCID: PMC6912184

Review Article

Bidirectional and Opposite Effects of Naïve Mesenchymal Stem Cells on Tumor Growth and Progression

Faramarz Rahmatizadeh 1,2,3 ORCID, Shiva Gholizadeh-Ghaleh Aziz 4 ORCID, Khodadad Khodadadi 5, Maryam Lale Ataei 2,6, Esmaeil Ebrahimie 7,8, Jafar Soleimani Rad 6,9 * , Maryam Pashaiasl 3,6,9,10 * ORCID

Cited by CrossRef: 12


1- Merckx G, Lo Monaco M, Lambrichts I, Himmelreich U, Bronckaers A, Wolfs E. Safety and Homing of Human Dental Pulp Stromal Cells in Head and Neck Cancer. Stem Cell Rev and Rep. 2021;17(5):1619 [Crossref]
2- Yang T, Zhiheng H, Zhanhuai W, Qian X, Yue L, Xiaoxu G, Jingsun W, Shu Z, Kefeng D. Increased RAB31 Expression in Cancer-Associated Fibroblasts Promotes Colon Cancer Progression Through HGF-MET Signaling. Front Oncol. 2020;10 [Crossref]
3- Navashenaq J, Shabgah A, Banach M, Jamialahmadi T, Penson P, Johnston T, Sahebkar A. The interaction of Helicobacter pylori with cancer immunomodulatory stromal cells: New insight into gastric cancer pathogenesis. Seminars in Cancer Biology. 2022;86:951 [Crossref]
4- Han P, Cao P, Hu S, Kong K, Deng Y, Zhao B, Li F.

Esophageal Microenvironment: From Precursor Microenvironment to Premetastatic Niche

. CMAR. 2020;Volume 12:5857 [Crossref]
5- Jafari A, Rezaei-Tavirani M, Farhadihosseinabadi B, Zali H, Niknejad H. Human amniotic mesenchymal stem cells to promote/suppress cancer: two sides of the same coin. Stem Cell Res Ther. 2021;12(1) [Crossref]
6- Sohrabi B, Dayeri B, Zahedi E, Khoshbakht S, Nezamabadi Pour N, Ranjbar H, Davari Nejad A, Noureddini M, Alani B. Mesenchymal stem cell (MSC)-derived exosomes as novel vehicles for delivery of miRNAs in cancer therapy. Cancer Gene Ther. 2022;29(8-9):1105 [Crossref]
7- Arab S, Alizadeh A, Asgharzade S. Tumor-resident adenosine-producing mesenchymal stem cells as a potential target for cancer treatment. Clin Exp Med. 2021;21(2):205 [Crossref]
8- Moore K, Murthy A, Graham-Gurysh E, Hingtgen S, Bachelder E, Ainslie K. Polymeric Biomaterial Scaffolds for Tumoricidal Stem Cell Glioblastoma Therapy. ACS Biomater Sci Eng. 2020;6(7):3762 [Crossref]
9- Silva M, Monteiro G, Fialho A, Bernardes N, da Silva C. Conditioned Medium From Azurin-Expressing Human Mesenchymal Stromal Cells Demonstrates Antitumor Activity Against Breast and Lung Cancer Cell Lines. Front Cell Dev Biol. 2020;8 [Crossref]
10- Goodarzi A, Valikhani M, Amiri F, Safari A. The mechanisms of mutual relationship between malignant hematologic cells and mesenchymal stem cells: Does it contradict the nursing role of mesenchymal stem cells?. Cell Commun Signal. 2022;20(1) [Crossref]
11- Li Y, Zhong X, Zhang Y, Lu X. Mesenchymal Stem Cells in Gastric Cancer: Vicious but Hopeful. Front Oncol. 2021;11 [Crossref]
12- Moskaleva E, Zhorova E, Semochkina Y, Shuvatova V, Rodina A, Saprykin V. Mechanisms of Stimulation of the Growth of Mouse Mammary Adenocarcinoma by Mesenchymal Stem Cells. Bull Exp Biol Med. 2021;171(1):141 [Crossref]