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Adv Pharm Bull. 2019;9(4): 685-689. doi: 10.15171/apb.2019.080
PMID: 31857975        PMCID: PMC6912173

Short Communication

10-Gingerol Inhibits Ovarian Cancer Cell Growth by Inducing G2 Arrest

Andrea Rasmussen 1 ORCID, Kaylee Murphy 2, David W. Hoskin 1,2,3 * ORCID

Cited by CrossRef: 16


1- Ediriweera M, Moon J, Nguyen Y, Cho S. 10-Gingerol Targets Lipid Rafts Associated PI3K/Akt Signaling in Radio-Resistant Triple Negative Breast Cancer Cells. Molecules. 2020;25(14):3164 [Crossref]
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3- Barboza J, Pereira F, Vasconcelos C, de Sousa Ribeiro M, Lopes A. Molecular mechanisms of action and chemosensitization of tumor cells in ovarian cancer by phytochemicals: A narrative review on pre‐clinical and clinical studies. Phytotherapy Research. 2023;37(6):2484 [Crossref]
4- Wala K, Szlasa W, Sauer N, Kasperkiewicz-Wasilewska P, Szewczyk A, Saczko J, Rembiałkowska N, Kulbacka J, Baczyńska D. Anticancer Efficacy of 6-Gingerol with Paclitaxel against Wild Type of Human Breast Adenocarcinoma. Molecules. 2022;27(9):2693 [Crossref]
5- Yücel Ç, Karatoprak G, Açıkara Ö, Akkol E, Barak T, Sobarzo-Sánchez E, Aschner M, Shirooie S. Immunomodulatory and anti-inflammatory therapeutic potential of gingerols and their nanoformulations. Front Pharmacol. 2022;13 [Crossref]
6- Liu M, Yang Y, Zhang M, Xue Y, Zheng B, Zhang Y, Liu Y, Chu X, Sun Z, Han X. Inhibition of human ether-à-go-go-related gene K+ currents expressed in HEK293 cells by three gingerol components from ginger. 2022;74(8):1133 [Crossref]
7- Deng B, Jiang X, Xu Y, Chen S, Cai M, Deng S, Ding W, Xu H, Zhang S, Tan Z, Chen R, Liu B, Zhang J. 10-Gingerol, a natural AMPK agonist, suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. Food Funct. 2022;13(6):3234 [Crossref]
8- Jhulki S, Pal A. Current Prospects of Phytochemical-Based Treatment for Ovarian Cancer: A Brief Review. Indian J Gynecol Oncolog. 2023;21(3) [Crossref]
9- Zhang X, Cai A, Gao Y, Zhang Y, Duan X, Men K. Treatment of Melanoma by Nano-conjugate-Delivered Wee1 siRNA. Mol Pharmaceutics. 2021;18(9):3387 [Crossref]
10- Zimmermann-Klemd A, Reinhardt J, Winker M, Gründemann C. Phytotherapy in Integrative Oncology—An Update of Promising Treatment Options. Molecules. 2022;27(10):3209 [Crossref]
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12- Guo J, Li Y, Yuan Y, Li X, Li X, Jiang X, Bai W, Jiao R. Cholesterol-lowering activity of 10-gingerol in HepG2 cells is associated with enhancing LDL cholesterol uptake, cholesterol efflux and bile acid excretion. Journal of Functional Foods. 2022;95:105174 [Crossref]